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17,828 grants matching crispr

Investigating a positive biological role for the A Beta peptide

$202,500
Thomas A Jongens · University Of Pennsylvania · R21 · FY2020 · AG

Understanding the chlamydial developmental cycle at the single cell level

$202,500
Scott S Grieshaber · University Of Idaho · R21 · FY2024 · AI

Single-cell characterization of antibiotic-induced heteroresistance

$202,500
Saeed F Tavazoie · Columbia University Health Sciences · R21 · FY2021 · AI

Role of heme oxygenase 2 in trafficking and regulation of myristoylated proteins

$202,500
Stephen P Goff · Columbia University Health Sciences · R21 · FY2020 · AI

Pathogenesis and CRISPR/Cas9 Correction of TCF4 Expansion in Fuchs Dystrophy

$202,500
Albert S Jun · Johns Hopkins University · R21 · FY2017 · EY

Impact of CRISPR-associated transposons on anti-phage immunity in Vibrio cholerae

$202,500
Samuel Henry Sternberg · Columbia University Health Sciences · R21 · FY2022 · AI

Transgenic & Knock-out Mouse

$202,414
Pamela L Mellon · University Of California, San Diego · P30 · FY2019 · DK

Light activated CRISPR epigenome editing in cocaine abuse

$202,369
Mary Kay Lobo · University Of Maryland Baltimore · R21 · FY2018 · DA

Characterizing the contribution of transcription-associated DNA-topoisomerase adducts to mutagenesis in cancer

$202,194
Steven A Roberts · Washington State University · R21 · FY2022 · CA

Organoid Acquired Resistance

$202,165
Sourav Bandyopadhyay · University Of California, San Francisco · U54 · FY2024 · CA

Selectable non-mosaic embryo editing

$202,122
Hiromitsu Nakauchi · Stanford University · R21 · FY2020 · OD

Rescuing ⍺-synuclein toxicity through neuron-specific enhancement of autophagy

$201,960
Jason Paul Chua · Johns Hopkins University · K08 · FY2023 · NS

Rescuing ⍺-synuclein toxicity through neuron-specific enhancement of autophagy

$201,960
Jason Paul Chua · Johns Hopkins University · K08 · FY2025 · NS

Rescuing ⍺-synuclein toxicity through neuron-specific enhancement of autophagy

$201,960
Jason Paul Chua · Johns Hopkins University · K08 · FY2024 · NS

Developing Homology-Independent Targeted Insertion (HITI) toolkits for molecular genetic manipulation of Drosophila melanogaster and Anopheles gambiae

$201,925
Paul A Garrity · Brandeis University · R21 · FY2019 · AI

Discovering the mechanisms-of-action of mistargeted anti-cancer agents

$201,925
Jason Sheltzer · Cold Spring Harbor Laboratory · R01 · FY2021 · CA

Biochemical mechanisms of Hedgehog signal transduction through primary cilia

$201,875
David R Raleigh · University Of California, San Francisco · R21 · FY2022 · HD

Intracellular Recognition of Fungi by the Innate Immune System

$201,875
Hiten D Madhani · University Of California, San Francisco · R21 · FY2021 · AI

Illuminating gene therapy

$201,875
Michael T McManus · University Of California, San Francisco · R21 · FY2023 · OD

A CRISPR-based modular transgenic system to advance in vivo investigations of angiogenesis and fibrosis

$201,875
Matthew J Wolf · University Of Virginia · R21 · FY2023 · OD

Reconstructing the Global Epistasis Network for Aging

$201,875
Hao Li · University Of California, San Francisco · R21 · FY2022 · AG

Identifying the mechanism of bacteriophage detection by cyclic-oligonucleotide signaling systems

$201,875
Joseph Bondy-Denomy · University Of California, San Francisco · R21 · FY2023 · AI

Establish a zebrafish genetic mosaic system for disease modeling and developmental biology

$201,875
Hui Zong · University Of Virginia · R21 · FY2018 · OD

Deciphering a novel lipid-based mechanism of innate immune modulation

$201,875
Suzanne M Noble · University Of California, San Francisco · R21 · FY2024 · AI

Split-GFP tagging and live imaging of hair cell proteins

$201,875
Jung-Bum Shin · University Of Virginia · R21 · FY2023 · DC