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30,917 grants matching tumor microenvironment

Combinatorial Targeting of Epigenomic and Microenvironmental Pathways to Suppress MAPK Inhibitor Resistance in Melanoma

$363,090
Roger S Lo · University Of California Los Angeles · R01 · FY2022 · CA

Combinatorial Targeting of Epigenomic and Microenvironmental Pathways to Suppress MAPK Inhibitor Resistance in Melanoma

$363,090
Roger S Lo · University Of California Los Angeles · R01 · FY2023 · CA

Analyzing protein homeostasis pathways in multiple myeloma stem-like cells

$363,090
Nami McCarty · University Of Texas Hlth Sci Ctr Houston · R01 · FY2022 · CA

Analyzing protein homeostasis pathways in multiple myeloma stem-like cells

$363,090
Nami McCarty · University Of Texas Hlth Sci Ctr Houston · R01 · FY2023 · CA

Reprogramming the Tumor Microenvironment to Improve Immunotherapy of Glioblastoma by Co-Targeting VEGF and Ang2

$363,077
Dai Fukumura · Massachusetts General Hospital · R01 · FY2025 · NS

CD8+ T Cell-Mediated Immunotherapy of Autochthonous SV40 T Antigen-Induced Tumors

$363,051
Todd D Schell · Pennsylvania State Univ Hershey Med Ctr · R01 · FY2014 · CA

Regulation of T cell Functions by the Breast Cancer Microenvironment

$363,029
Matthew F Krummel · University Of California, San Francisco · R01 · FY2009 · CA

Project 2: Targeting MERTK to improve outcomes for EGFR-mutated NSCLC

$363,004
Douglas K Graham · Emory University · P50 · FY2020 · CA

Identification and targeting of mechanisms specific to glioma stem cells in glioblastoma

$362,964
Daniel J Brat · Northwestern University At Chicago · R01 · FY2021 · CA

Therapeutic Mechanism of CD47 Blockade in Suppressing Melanoma Metastasis

$362,913
Alexander D Boiko · Cedars-Sinai Medical Center · R01 · FY2024 · CA

STING-dependent activation of Natural Killer cells by viral and tumor DNA

$362,894
David H Raulet · University Of California Berkeley · R01 · FY2020 · AI

Crosstalk between glioma cells & immune cells in the tumor microenvironment: Ther

$362,892
Maria G Castro · University Of Michigan At Ann Arbor · R01 · FY2013 · NS

Targeting oncogenic epigenetic mechanisms in IDHmut/ATRXloss Astrocytoma

$362,823
Yunqing Li · Hugo W. Moser Res Inst Kennedy Krieger · R01 · FY2024 · NS

Ubiquitinated Proteins in Exosomes of Immune Suppressive Myeloid Cells

$362,818
Catherine C. Fenselau · Univ Of Maryland, College Park · R01 · FY2017 · GM

Ubiquitinated Proteins in Exosomes of Immune Suppressive Myeloid Cells

$362,818
Catherine C. Fenselau · Univ Of Maryland, College Park · R01 · FY2016 · GM

Ubiquitinated Proteins in Exosomes of Immune Suppressive Myeloid Cells

$362,818
Catherine C. Fenselau · Univ Of Maryland, College Park · R01 · FY2015 · GM

Developing informatics tools to predict virtual spatial transcriptomics data with single-cell resolution in large-scale studies

$362,813
Mingyao Li · University Of Pennsylvania · R01 · FY2024 · LM

New protein engineering-based tools and technologies for characterizing cell surface proteolysis in cancer cells for novel neo-epitope biomarkers and drug targets

$362,803
James A Wells · University Of California, San Francisco · R01 · FY2020 · CA

Tumor and Stromal Metalloproteinases in Breast Cancer

$362,783
Lynn M Matrisian · Vanderbilt University · R01 · FY2009 · CA

A Phase I safety & immunogenicity study of an HPV16-specific therapeutic protein, TA-CIN, administered intratumorally with chemoradiation in patients with cervical cancer stratified by HPV16 infection

$362,763
T.-C. Wu · Johns Hopkins University · P50 · FY2022 · CA

Ultra-Small Epigenetic-Regulating Nanocarrier for Enhanced Synthetic Lethal Therapy

$362,741
Jingjing Sun · University Of Nebraska Medical Center · R01 · FY2024 · CA

Project 2: Effect of HTLV-1 Viral Oncogenes on the Bone Microenvironment during tumor growth and progression in ATL

$362,735
Katherine Nelson Weilbaecher · Ohio State University · P01 · FY2021 · CA

Developing informatics tools to predict virtual spatial transcriptomics data with single-cell resolution in large-scale studies

$362,728
Mingyao Li · University Of Pennsylvania · R01 · FY2025 · LM

Adhesive regulation during cell migration

$362,722
Anna Huttenlocher · University Of Wisconsin-Madison · R01 · FY2025 · CA

Adhesive regulation during cell migration

$362,722
Anna Huttenlocher · University Of Wisconsin-Madison · R01 · FY2022 · CA