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17,828 grants matching “crispr”
A 3D ex vivo orthotopic xenograft screening platform to identify radiosensitization targets and druggability in glioma
$209,561Scott R Floyd · Duke University · R21 · FY2019 · CA
Shotgun method for massive mutational interrogation of the entire human genome
$209,375Andrei Alexandrov · Yale University · R21 · FY2017 · HG
Identification of Novel Regulators for Neutrophil Development and Lifespan
$209,375Wenwen Tang · Yale University · R21 · FY2025 · AI
A comprehensive gene repair therapy for FKRP neuromuscular diseases
$209,375Charles P Emerson · Univ Of Massachusetts Med Sch Worcester · R21 · FY2019 · NS
Identification of Genes Important for Rejuvenation of Aged Hematopoietic Stem Cells
$209,375Hong Zhang · Univ Of Massachusetts Med Sch Worcester · R21 · FY2019 · AG
Host genes controlling rodent protoparvovirus tissue and species tropism
$209,375Peter Tattersall · Yale University · R21 · FY2022 · AI
Repurposing systemic RNAi to simplify genome editing in nematodes
$209,375Sean Patrick Ryder · Univ Of Massachusetts Med Sch Worcester · R21 · FY2020 · HG
Functionally dissecting the transcriptional regulatory network of the innate immune response using CRISPR-effectors
$209,375Rene Maehr · Univ Of Massachusetts Med Sch Worcester · R21 · FY2016 · AI
Helper-dependent adenoviral vectors for targeted in vivo gene delivery to both CD4 T cells and hematopoietic progenitors
$209,375Richard E. Sutton · Yale University · R21 · FY2018 · AI
CRISPR screen of microRNAs that regulate the regenertive potential of hematopoietic stem cells
$209,375Hong Zhang · Univ Of Massachusetts Med Sch Worcester · R21 · FY2018 · AG
Defining epistatic interactions among Coxiella burnetii effector proteins using a CRISPRi approach
$209,375Craig R. Roy · Yale University · R21 · FY2023 · AI
RNA Pseudouridylation During Flavivirus Infection
$209,375Wendy Victoria Gilbert · Yale University · R21 · FY2020 · AI
Shotgun method for massive mutational interrogation of the entire human genome
$209,375Andrei Alexandrov · Yale University · R21 · FY2018 · HG
Discovery of NR4A1/2 ligands controlling tissue-resident memory T (Trm) cells
$209,375Fabio Rinaldo Santori · Yale University · R21 · FY2018 · AI
Structural Basis of Programmable DNA-Insertion via Cryo-EM Studies of CRISPR-Associated TnsC
$209,370Elizabeth Kellogg · Cornell University · R01 · FY2023 · GM
Interrogating and Targeting Microglia Phagocytosis in Alzheimerâs Disease
$209,253Brandon Blake Holmes · University Of California, San Francisco · K08 · FY2025 · NS
Project 4: Mechanisms and Impacts of PCB Resistance in Fish
$209,021Mark E Hahn · Boston University Medical Campus · P42 · FY2019 · ES
Epigenetic mechanisms of mammalian tissue aging
$208,903Payel Sen · National Institute On Aging · ZIA · FY2019 · AG
Preclinical development of gene-edited human hematopoietic stem cells
$208,845Rodger Novak · Harvard University · U19 · FY2019 · HL
A live attenuated vaccine for leishmaniasis
$208,827Abhay R. Satoskar · Ohio State University · R21 · FY2018 · AI
Modeling human prostate cancer by cellular reprogramming
$208,800Michael M. Shen · Columbia University Health Sciences · R21 · FY2016 · CA
(PQ4) Mutations in the histone chaperone DAXX drive pancreatic neuroendocrine tumors not ductal adenocarcinomas
$208,800Guillermina Lozano · University Of Tx Md Anderson Can Ctr · R21 · FY2016 · CA
Role of A-Kinase Anchoring Proteins in Hepatotoxin- Induced Liver Fibrosis
$208,750Komal Ramani · Cedars-Sinai Medical Center · R21 · FY2019 · ES
Cannabinoids as an environmental risk factor of testicular cancer: Assessment using cell culture models of human and mouse primordial germ cells and by exposure of pregnant mice
$208,750Toshihiro Shioda · Massachusetts General Hospital · R21 · FY2025 · DA
Characterization of a novel mouse with deficient calcium flux
$208,750R. Suzanne Zukin · Albert Einstein College Of Medicine · R21 · FY2019 · NS