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17,054 grants matching genome editing

Skeletal Myosin-Binding Protein C: Defining Function Across Scales Using a Zebrafish Model System.

$201,960
David M Warshaw · University Of Vermont & St Agric College · R21 · FY2024 · AR

Developing Homology-Independent Targeted Insertion (HITI) toolkits for molecular genetic manipulation of Drosophila melanogaster and Anopheles gambiae

$201,925
Paul A Garrity · Brandeis University · R21 · FY2019 · AI

Methods and Analysis

$201,909
Eve Van Cauter · Northwestern University At Chicago · P01 · FY2018 · AG

Core D - IDD Models Core

$201,904
John P Svaren · University Of Wisconsin-Madison · U54 · FY2018 · HD

A CRISPR-based modular transgenic system to advance in vivo investigations of angiogenesis and fibrosis

$201,875
Matthew J Wolf · University Of Virginia · R21 · FY2023 · OD

Using human intestinal organoids to model IBD pathogenesis

$201,875
Ophir D Klein · University Of California, San Francisco · R21 · FY2020 · DK

Tag-ChIP-MS for analysis of chromatin-level regulation of DNA repair

$201,875
Stephen J. Kron · University Of Chicago · R21 · FY2017 · CA

Split-GFP tagging and live imaging of hair cell proteins

$201,875
Jung-Bum Shin · University Of Virginia · R21 · FY2023 · DC

Dissecting the mechanism of pyrantel resistance in hookworm

$201,875
John M Hawdon · George Washington University · R21 · FY2024 · AI

Next Generation TOP1 Inhibition for the Treatment of Uterine Serous Carcinoma

$201,750
Scott H Kaufmann · Mayo Clinic Rochester · P50 · FY2024 · CA

Core Essential Genes in Primary Effusion Lymphoma Cell Lines

$201,623
Eva Henriette Gottwein · Northwestern University At Chicago · R21 · FY2016 · CA

Hematopoietic stem cell based gene therapy of breast cancer

$201,623
Andre Michael Lieber · University Of Washington · R21 · FY2015 · CA

Variants underlying sex bias in Systemic Lupus Erythematosus

$201,377
Laura Carrel · Pennsylvania State Univ Hershey Med Ctr · R21 · FY2023 · AI

Generating novel mouse tools to investigate brain region and cell-type specific circadian molecular mechanisms of reward and motivation

$201,344
Ryan W Logan · University Of Pittsburgh At Pittsburgh · R33 · FY2020 · DA

Deciphering the role of lipid metabolism pathways in the RPE and their implications for AMD

$201,250
Venkata Ramana Murthy Chavali · University Of Pennsylvania · R21 · FY2019 · EY

Regulation of adipose tissue inflammation by the miR-181 family

$201,250
Jorge Henao-Mejia · University Of Pennsylvania · R21 · FY2018 · DK

Genetically enabling Hydra oligactis for comparative studies in development, regeneration and aging.

$201,250
Celina Juliano · University Of California At Davis · R21 · FY2025 · OD

Regulation of adipose tissue inflammation by the miR-181 family

$201,250
Jorge Henao-Mejia · University Of Pennsylvania · R21 · FY2017 · DK

Durability of a gene editing therapy that restores dystrophin in a humanized mouse model of Duchenne muscular dystrophy

$201,250
Courtney S Young · Myogene Bio, Llc · R21 · FY2025 · TR

Regulation of adipose tissue inflammation by the miR-181 family

$201,250
Jorge Henao-Mejia · University Of Pennsylvania · R21 · FY2016 · DK

Molecular Identity of Maternal Regulators of the Egg to Embryo Transition

$201,250
Mary C Mullins · University Of Pennsylvania · R21 · FY2018 · HD

A novel and tractable model to address telomere dysfunction in a human tissue

$201,250
Frederick Bradley Johnson · University Of Pennsylvania · R21 · FY2017 · AG

Core D - IDD Models Core

$201,218
John P Svaren · University Of Wisconsin-Madison · U54 · FY2020 · HD

Childhood Hematological Malignancies Training Program

$201,210
Charles G. Mullighan · St. Jude Children'S Research Hospital · T32 · FY2019 · CA

Mechanistic Characterization of Calcium-Activated Chloride Channels in Retinal Pigment Epithelium

$201,196
Tingting Yang · Columbia University Health Sciences · R01 · FY2019 · GM