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17,828 grants matching crispr

Defining mechanisms of diverse CRISPR-Cas complexes

$225,000
Dipali Gurudutt Sashital · Iowa State University · R35 · FY2024 · GM

SBIR Phase I: A block copolymer delivery system for the Cpf1 ribonucleoprotein

$225,000
Kunwoo Lee · Genedit Inc · · FY2019 · TIP

Development of CRISPR/Cas system for study of trans-sialidase family genes in T. cruzi

$225,000
Rick L Tarleton · University Of Georgia · R21 · FY2017 · AI

Denaturation-Free DNA Target Enrichment and Direct Sequencing of Large Chromosomal Segments

$224,981
Johannes Dapprich · Generation Biotech, Llc · R43 · FY2019 · HG

Malaria parasite harbors a unique protein lysine methyltransferase targeting both chromatin and motility machinery

$224,875
Jun Miao · University Of South Florida · R21 · FY2023 · AI

Structure-based optimization of a novel pharmacological chaperone therapy for MPSIIIC

$224,873
Srikanth Singamsetty · Phoenix Nest, Inc. · R41 · FY2017 · HD

Core C - Functional Genomics and Computational Biology Core

$224,864
E. John Wherry · University Of Pittsburgh At Pittsburgh · P01 · FY2020 · AI

Targeted Gene Insertion by Directed Evolution of ΦC31 Integrase for Therapeutic Gene Editing

$224,854
Ruby Yanru Chen-Tsai · Applied Stemcell, Inc. · R44 · FY2020 · GM

Genome-wide CRISPR screen to identify pro-myogenic factors for cell therapy of DMD

$224,725
Louis M Kunkel · Myofinity Biosciences Inc · R41 · FY2018 · AR

Core D: Mouse Genetics and Genomics Core

$224,691
Anne E. Kwitek · Medical College Of Wisconsin · P01 · FY2022 · HL

Core D: Mouse Genetics and Genomics Core

$224,691
Anne E. Kwitek · Medical College Of Wisconsin · P01 · FY2020 · HL

Core D: Mouse Genetics and Genomics Core

$224,691
Anne E. Kwitek · Medical College Of Wisconsin · P01 · FY2021 · HL

Insect cell lines for glycoprotein structural biology and mannose-dependent protein drugs

$224,597
Carol D Blair · Glycobac, Llc · R43 · FY2020 · GM

ModRNA-based Direct Programming of Universal Donor hiPSCs into Immune Evasive Beta Cells

$224,570
Xiaojun Lian · Pennsylvania State University, The · R56 · FY2024 · DK

Effective engineering of the mitochondrial genome

$224,564
Leah Justine Hogdal · B-Mogen Biotechnologies, Inc. · R43 · FY2017 · GM

Investigating the roles of RNA-binding proteins Nocte and PRRC2 in mRNA translation and age-related neurodegeneration using Drosophila and mouse models

$224,533
Weidong Wang · National Institute On Aging · ZIA · FY2022 · AG

improving Cas9 mediated homologous recombination in pluripotent stem cells

$224,518
Jifeng Zhang · Applied Stemcell, Inc. · R41 · FY2016 · GM

Developing an in vivo toolbox to interrogate the intracellular trafficking and killing of Aspergillus spores

$224,491
Emily Rosowski · Clemson University · R21 · FY2022 · AI

Drug target identification using CRISPRi/a screening

$224,455
Timothy R Peterson · Bioio, Llc · R41 · FY2020 · GM

Science Core

$224,432
Marc Monot · University Of California Los Angeles · P01 · FY2025 · AI

Regulation of cGAS-Mediated Cytosolic DNA Sensing Pathway

$224,400
Shitao Li · Oklahoma State University Stillwater · R21 · FY2018 · AI

Elucidating the function of PAX3-FOXO1 in rhabdomyosarcoma with molecular reporters and next-generation genome editing

$224,400
Christopher Vakoc · Cold Spring Harbor Laboratory · R21 · FY2021 · CA

Genome-wide screening for host lncRNAs regulating host defense against Mycobacterial infection in macrophages

$224,400
Yong Cheng · Oklahoma State University Stillwater · R21 · FY2022 · AI

Identify novel modulators of regulatory T cell function from the dynamic cis-proteomes

$224,375
Yongqiang Feng · St. Jude Children'S Research Hospital · R21 · FY2022 · AI

Engineering Yeast towards High Titer Production of Monoterpene Indole Alkaloid Natural Products

$224,328
Yi Tang · University Of California Los Angeles · R01 · FY2020 · AT