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17,828 grants matching crispr

CRISPR/Cas9 guided production of genetically engineered pigs lacking CD8+ T-cells

$241,500
Kiho Lee · Virginia Polytechnic Inst And St Univ · R21 · FY2016 · OD

Genetically enabling Hydra oligactis for comparative studies in development, regeneration and aging.

$241,500
Celina Juliano · University Of California At Davis · R21 · FY2024 · OD

Using epigenome editing of transcriptional enhancers to regulate adult visual cortical plasticity

$241,500
Anne Elizabeth West · Duke University · R21 · FY2023 · EY

Intracellular Recognition of Fungi by the Innate Immune System

$241,500
Hiten D Madhani · University Of California, San Francisco · R21 · FY2020 · AI

How do dominant PMP2 mutations cause demyelinating neuropathy?

$241,500
Steven S Scherer · University Of Pennsylvania · R21 · FY2018 · NS

Molecular Identity of Maternal Regulators of the Egg to Embryo Transition

$241,500
Mary C Mullins · University Of Pennsylvania · R21 · FY2017 · HD

Dissecting and reconstructing the molecular roadmaps of cellular reprogramming to iPSCs in single-cell resolution

$241,418
Jian Shu · Massachusetts General Hospital · R00 · FY2022 · HD

Systematic mapping and prediction of gene-enhancer connections

$241,395
Jesse M Engreitz · Stanford University · R00 · FY2022 · HG

Modulation of Lassa Virus vRNP Activity By Host Cell Factors

$241,266
Juan C. De La Torre · Scripps Research Institute, The · R21 · FY2018 · AI

Core D: CRISPRi/a Core

$241,139
Martin Kampmann · J. David Gladstone Institutes · U54 · FY2016 · NS

Role of DNA sensing pathways in KSHV associated cancers

$241,098
Zhe Ma · University Of Florida · R00 · FY2022 · CA

Informatics Infrastructure and Bioinformatics Analysis

$241,071
Steven E Brenner · University Of California, San Francisco · P01 · FY2024 · AI

GENOMICS AND GENOME ENGINEERING CORE

$240,998
Kristen Lynn Jepsen · University Of California, San Diego · P50 · FY2015 · GM

Role for Circular RNAs in Compulsive Cocaine Intake

$240,939
Paul J Kenny · Icahn School Of Medicine At Mount Sinai · P01 · FY2021 · DA

Evolutionary and functional consequences of structural genetic variation in Drosophila

$240,920
Mahul Chakraborty · Texas A&M University · R00 · FY2025 · GM

Exploring novel regulatory mechanisms underlying enhancer activation and cell fate transition

$240,907
Kaixiang Cao · Case Western Reserve University · R00 · FY2021 · HD

A New Method for Mosaic Analysis of Clonal Mutations in Mice

$240,875
Yuan Zhuang · Duke University · R21 · FY2019 · OD

Therapeutic evaluation in GEM pancreatic model

$240,865
Terry Van Dyke · Division Of Basic Sciences - Nci · ZIA · FY2015 · CA

Organoid modeling to determine and reverse age-related epigenetic changes contributing to risk of colorectal cancer

$240,845
Stephen B Baylin · Johns Hopkins University · R01 · FY2021 · CA

In vivo CRISPR-screening of novel cancer cell-intrinsic targets that sensitize to local ionizing radiation, and possible combination with systemic checkpoint blockade.

$240,831
Ralph R Weichselbaum · University Of Chicago · R21 · FY2022 · CA

A Molecular Signaling Pathway Underlying Differential Predisposition of ApoE4 Genotype to Alzheimer's Disease

$240,710
Yu-Wen Alvin Huang · Brown University · R00 · FY2020 · AG

Role of Type I and III Interferons in Shaping Influenza A Virus Dynamics Within and Between Hosts

$240,709
Anice C Lowen · Emory University · R21 · FY2023 · AI

Characterizing the Function of the Periplasmic Protease Tsp in Chlamydial Secondary Differentiation

$240,625
Scot P Ouellette · University Of Nebraska Medical Center · R21 · FY2023 · AI

Role of Pld4 in nucleic acid sensing and interferon production

$240,625
David Nemazee · Scripps Research Institute, The · R21 · FY2017 · AI

Zhao - Proj 2

$240,566
Siming Zhao · Dartmouth College · P20 · FY2024 · GM