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17,828 grants matching crispr

Investigating the role of cGAS signaling and microglial senscence in tauopathy

$244,020
Sadaf Amin · Washington University · R00 · FY2025 · AG

Patterns and Mechanisms Underlying Somatic Mutations Across Long-Lived Bats

$244,019
Juan Manuel Vazquez · Pennsylvania State University, The · R00 · FY2025 · AG

Programmed DNA Damage and its Role in Alzheimer's Disease and Related Dementias

$244,019
Sarah Elizabeth Kargbo-Hill · University Of Michigan At Ann Arbor · R00 · FY2025 · AG

Integration of circadian and homeostatic signals in a peptidergic circuit in Drosophila

$243,959
Annika Fitzpatrick Barber · Rutgers, The State Univ Of N.J. · R00 · FY2020 · NS

Mitochondrial retrograde signaling in RPE heterogeneity

$243,902
Sayantan Datta · Emory University · R00 · FY2023 · EY

Predictive biomarker of BET bromodomain inhibitor in Small cell lung cancer

$243,898
Haobin Chen · Division Of Basic Sciences - Nci · ZIA · FY2022 · CA

Deciphering Mechanisms of Nitrogen-Containing Bisphosphonates

$243,884
Lauren Elizabeth Surface · University Of Michigan At Ann Arbor · R00 · FY2023 · AR

Identification and Characterization of Novel Metabolic Regulators in Mouse and Human Liver

$243,836
Ling Yang · Temple Univ Of The Commonwealth · K22 · FY2019 · HL

Three-dimensional human epithelial cultures as a model for evaluation of flavivirus-host interactions driving infection in the skin

$243,750
Susan R. Weiss · University Of Pennsylvania · R21 · FY2022 · AI

Identification of novel Toxoplasma genes involved in host-parasite interactions

$243,750
Sebastian Lourido · Whitehead Institute For Biomedical Res · R21 · FY2017 · AI

Development of FRESH (Fast Rescue Employing Self-Helper virus) - a rapid, generalizable method to rescue infectious virus from noninfectious genomic material

$243,750
Lauren Marie Oldfield · J. Craig Venter Institute, Inc. · R21 · FY2020 · AI

Genome Engineering Core

$243,747
Frederic D Bushman · University Of Pennsylvania · P01 · FY2025 · AI

Using CRISPR tools to uncover the role of CREB-gene regulation in drug abuse

$243,729
Peter James Hamilton · Virginia Commonwealth University · R00 · FY2022 · DA

Investigating the role of KLF5 genomic alterations in tumorigenesis

$243,715
Xiaoyang Zhang · University Of Utah · R00 · FY2020 · CA

Discovery of viral and host pathways that protect HIV-infected macrophages from NK cell ADCC

$243,713
Kiera L. Clayton · Univ Of Massachusetts Med Sch Worcester · R21 · FY2025 · AI

Developing Remyelination Strategies for Demyelinating Optic Neuropathies Using Human Pluripotent Stem Cells

$243,596
Xitiz Chamling · Johns Hopkins University · R00 · FY2023 · EY

Targeting Glutamine Uptake via ASCT2 Inhibition in MYCN-amplified Neuroblastomas

$243,398
Eric James Rellinger · University Of Kentucky · P20 · FY2025 · GM

Genome Editing Core

$243,368
Peng Yi · Joslin Diabetes Center · P30 · FY2023 · DK

Consequences of myosin-1G dimerization on its regulated interaction with actin

$243,298
Sarah Heissler · Ohio State University · K22 · FY2018 · HL

Consequences of myosin-1G dimerization on its regulated interaction with actin

$243,293
Sarah Heissler · Ohio State University · K22 · FY2019 · HL

Mechanisms and Consequences of Tau Internalization and Aggregation in the Central Nervous System

$243,215
Jennifer Nicole Rauch · University Of Massachusetts Amherst · R00 · FY2022 · AG

Mechanisms and Consequences of Tau Internalization and Aggregation in the Central Nervous System

$243,215
Jennifer Nicole Rauch · University Of Massachusetts Amherst · R00 · FY2021 · AG

Mechanisms and Consequences of Tau Internalization and Aggregation in the Central Nervous System

$243,215
Jennifer Nicole Rauch · University Of Massachusetts Amherst · R00 · FY2023 · AG

High Throughput Screening Shared Resource

$243,162
Bruce Arthur Posner · Ut Southwestern Medical Center · P30 · FY2025 · CA

Novel sources of endogenous DNA damage in hematopoietic stem progenitor cells

$243,135
Moonjung Jung · Rockefeller University · K99 · FY2020 · HL