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64,565 grants matching drug discovery

Development/Validation of Rete Testis Microcannulation for the Assessment of Novel Chemical Scaffolds That Penetrate the Blood Testis Barrier

$672,668
Henry L Wong · University Of Minnesota · R33 · FY2023 · HD

Discovering Affective Drug Combinations for Treating Covid-19

$672,569
Eytan Ruppin · Division Of Basic Sciences - Nci · ZIA · FY2020 · CA

Hemopexin as an Early Biomarker of Anthracycline Cardiac Toxicity

$672,532
Aarti Asnani · Beth Israel Deaconess Medical Center · R01 · FY2022 · HL

Development of a Miniature Mass Spectromtry System for Point-of-Care Applications

$672,527
Zheng Ouyang · Purspec Technologies, Inc. · R44 · FY2017 · GM

Lead Optimization of Lapatinib Analogs for Human African Trypanosomiasis

$672,488
Kojo Mensa-Wilmot · University Of Georgia · R56 · FY2014 · AI

RNA METABOLISM IN TRYPANOSOMES

$672,251
Elisabetta Ullu · Yale University · R37 · FY2013 · AI

PD-1/PD-L1 modulation in cancer therapy

$672,206
Drew M. Pardoll · Johns Hopkins University · R01 · FY2020 · CA

Use of silver nanostructures on microtransponders in ultra-sensitive assay

$672,201
Wlodek Mandecki · Pharmaseq, Inc. · R44 · FY2010 · CA

Structural, mechanistic, & evolutionary characterization of tetracycline destructases

$672,172
Gautam Dantas · Washington University · U01 · FY2025 · AI

Novel Therapeutics for Cardiovascular Disease

$672,130
Sasantha Jeson Sangaralingham · Mayo Clinic Rochester · R01 · FY2024 · HL

T7 RNA polymerase engineering and RNA amplification

$672,066
Andrew D Ellington · Accacia International, Inc. · R42 · FY2007 · GM

Targeting RAGE/DIAPH1: Novel Therapeutic Strategy for Diabetic Complications

$672,000
Ann Marie Schmidt · New York University School Of Medicine · R01 · FY2020 · DK

The Impact of Pharmaceutical Industry Messaging on the Opioid Crisis among U.S. Military Veterans

$671,958
Christopher Keith Haddock · Ndri-Usa, Inc. · R01 · FY2023 · DA

Anti-folate chemotype protein degraders

$671,951
James Inglese · National Center For Advancing Translational Sciences · ZIA · FY2025 · TR

JAK-STAT Inhibition to Reduce Racial Disparities in Kidney Disease

$671,935
Opeyemi Ayodeji Olabisi · Duke University · R01 · FY2022 · MD

Mechanisms of FGF Receptor Regulation and Signaling

$671,931
Moosa Mohammadi · New York University School Of Medicine · R01 · FY2016 · DE

HTS Assays for Modulators of GPCR Signaling

$671,897
Robert G Lowery · Bellbrook Labs, Llc · R44 · FY2009 · NS

Integrated ligand and target discovery by chemical proteomics for glioblastoma treatment.

$671,855
Paul S Mischel · Stanford University · R01 · FY2022 · CA

Structural Studies and Drug Discovery to Interrogate the Function of Neuronal SLC4 Transporters

$671,775
Daniel Wacker · Icahn School Of Medicine At Mount Sinai · R01 · FY2025 · NS

Novel Protein Aggregation Inhibitors and Upper Motor Neuron Stabilizers for ALS and other Neurodegenerative Diseases

$671,753
Pembe Hande Ozdinler · Northwestern University At Chicago · R01 · FY2019 · AG

Screening for Molecules that Promote Photoreceptor Synaptogenesis

$671,689
Donald J Zack · Johns Hopkins University · U01 · FY2018 · EY

Discovery of First-in-class WDR5 PROTACs as a Novel Therapeutic Strategy for MLL-rearranged Leukemias

$671,604
Jian Jin · Icahn School Of Medicine At Mount Sinai · R01 · FY2022 · CA

A network approach to interrogate cellular plasticity and drug resistance in cancer

$671,594
Rosemary J Akhurst · University Of California, San Francisco · R01 · FY2024 · CA

It's a tug of war: structure, consequences, and inhibition of CXCR4 and ACKR3 responses to lymphocyte chemoattractant CXCL12

$671,571
Tracy M Handel · University Of California, San Diego · R01 · FY2023 · AI

Reversible Covalent BTK Degraders as the Next Generation Targeted Therapy to Treat B-cell Malignancies

$671,549
Jin Wang · Baylor College Of Medicine · R01 · FY2020 · CA