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17,054 grants matching genome editing

Elucidating how intracellular bacterial pathogens hijack host intercellular communication to promote spread

$249,000
Rebecca L Lamason · Massachusetts Institute Of Technology · R00 · FY2017 · GM

Characterizing the pathogenesis and targeted therapeutics of Wilms' Tumor 1 (WT1) mutations in AML

$249,000
Haijiao Zhang · Oregon Health & Science University · R00 · FY2022 · CA

Mechanisms of CRISPR-mediated immunity and applications beyond editing

$249,000
Andrew Santiago-Frangos · University Of Pennsylvania · R00 · FY2025 · GM

Elucidating how intracellular bacterial pathogens hijack host intercellular communication to promote spread

$249,000
Rebecca L Lamason · Massachusetts Institute Of Technology · R00 · FY2018 · GM

Molecular mechanisms regulating chromatin looping in time and space

$249,000
Anders Sejr Hansen · Massachusetts Institute Of Technology · R00 · FY2021 · GM

Genetic variation impacting the airway smooth muscle in children with asthma

$249,000
Walter Eckalbar · University Of California, San Francisco · R00 · FY2020 · HL

Mechanism and Therapeutic Application of RNA-Guided Immune Systems

$249,000
Christof Fellmann · J. David Gladstone Institutes · R00 · FY2019 · GM

Functional dissection of oncogenic enhancers

$249,000
Daniel Herranz · Rbhs -Cancer Institute Of New Jersey · R00 · FY2017 · CA

Elucidating the role of support signaling in promoting minimal residual disease in mouse models of oncogene-driven lung cancer

$249,000
Aria Vaishnavi · University Of Tx Md Anderson Can Ctr · R00 · FY2025 · CA

Functional characterization of novel oncogenic loci driving progression and immune response in gastrointestinal cancer

$249,000
Yuan-Hung Lo · University Of Tx Md Anderson Can Ctr · R00 · FY2025 · CA

Overcome the lineage plasticity conferred targeted therapy resistance in advanced prostate cancer

$249,000
Ping Mu · Ut Southwestern Medical Center · R00 · FY2018 · CA

Tspan14 expression and function in cardiovascular disease

$249,000
Vivian Lee-Kim · Ut Southwestern Medical Center · R00 · FY2024 · HL

Dissecting reciprocal interactions between cancer cells and endothelial cells in SCLC liver metastasis.

$249,000
Rui Tang · Washington University · R00 · FY2025 · CA

Investigation and functional characterization of new drivers of mesenchymal tumorigenesis.

$249,000
Jlenia Guarnerio · Cedars-Sinai Medical Center · R00 · FY2018 · CA

Functional assessment of enhancer-gene interactions in vivo

$249,000
Evgeny Kvon · University Of California-Irvine · R00 · FY2020 · HG

Deep Learning Approaches to Decipher the Impact of Mobile Element Insertion on Alternative Splicing in Neurological Disorders

$249,000
Dadi Gao · Massachusetts General Hospital · R00 · FY2025 · NS

Evolutionary and functional consequences of structural genetic variation in Drosophila

$249,000
Mahul Chakraborty · Texas A&M University · R00 · FY2023 · GM

Function and Targeting of ETV6 in Ewing Sarcoma

$249,000
Yuan Gao · Case Western Reserve University · R00 · FY2024 · CA

A universal genome editing strategy to develop an airway stem cell therapy for cystic fibrosis

$249,000
Sriram Vaidyanathan · Research Inst Nationwide Children'S Hosp · R00 · FY2022 · HL

A pan-cancer atlas of driver mutations in >100,000 patients based on a hypothesis-driven combined computational and experimental approach

$249,000
Felix Dietlein · Boston Children'S Hospital · R00 · FY2022 · CA

The role of HIF regulated genes and genomic regions in trophoblast invasion

$249,000
Geetu Tuteja · Iowa State University · R00 · FY2015 · HD

Transcriptional networks controlling molting in C. elegans and B. malayi

$249,000
Jordan David Ward · University Of California Santa Cruz · R00 · FY2018 · GM

Revealing Principles of Subcellular RNA Localization by Proximity Labeling

$249,000
Furqan Fazal · Baylor College Of Medicine · R00 · FY2022 · HG

Large-scale CRISPR screening of essential calcium-related genes in the human parasite Tr. cruzi

$249,000
Noelia Lander · University Of Cincinnati · R00 · FY2021 · AI

Deep learning approaches to decipher the impact of mobile element insertion on alternative splicing in neurological disorders

$249,000
Dadi Gao · Massachusetts General Hospital · R00 · FY2023 · NS