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30,917 grants matching tumor microenvironment

PROTAC Targeting of Tip60 in Syngeneic Cancer Models Using Cereblon Knock-in Mice

$388,077
Wayne William Hancock · Children'S Hosp Of Philadelphia · R01 · FY2022 · CA

PROTAC Targeting of Tip60 in Syngeneic Cancer Models Using Cereblon Knock-in Mice

$388,077
Wayne William Hancock · Children'S Hosp Of Philadelphia · R01 · FY2023 · CA

Project 3: Modulation of the head and neck tumor immune microenvironment by targeting the TAM family of receptors

$388,023
Deric L Wheeler · University Of Wisconsin-Madison · P50 · FY2025 · CA

Targeting DNA repair to eradicate TKi-refractory/resistant CML and Ph+ALL

$388,003
Tomasz Skorski · Temple Univ Of The Commonwealth · R01 · FY2022 · CA

New Multi-Drug Resistance Mechanism in Multiple Myeloma

$388,003
Shigeki Miyamoto · University Of Wisconsin-Madison · R01 · FY2021 · CA

Targeting DNA repair to eradicate TKi-refractory/resistant CML and Ph+ALL

$387,997
Tomasz Skorski · Temple Univ Of The Commonwealth · R01 · FY2021 · CA

Explore the therapeutic potential of small-molecule immune modulators

$387,977
Chuo Chen · Ut Southwestern Medical Center · R01 · FY2019 · CA

Explore the therapeutic potential of small-molecule immune modulators

$387,977
Chuo Chen · Ut Southwestern Medical Center · R01 · FY2021 · CA

Explore the therapeutic potential of small-molecule immune modulators

$387,977
Chuo Chen · Ut Southwestern Medical Center · R01 · FY2020 · CA

Targeting tumorigenic pathways in glioblastoma with oncolytic HSV

$387,855
Samuel D Rabkin · Massachusetts General Hospital · R01 · FY2022 · CA

Targeting tumorigenic pathways in glioblastoma with oncolytic HSV

$387,855
Samuel D Rabkin · Massachusetts General Hospital · R01 · FY2023 · CA

Tumor Immunology & Host Response

$387,787
Max S. Wicha · University Of Michigan At Ann Arbor · P30 · FY2016 · CA

Coordinating tumor differentiation and immune suppression with the metabolic state and treatment outcome

$387,785
Hans Ragnar Widlund · Brigham And Women'S Hospital · R01 · FY2019 · CA

Project 1: Targeting the PD-1 pathway in HCC

$387,766
Ahmed Kaseb · University Of Tx Md Anderson Can Ctr · P50 · FY2020 · CA

Biomarker Developmental Laboratory (BDL)

$387,766
Steven J Skates · Massachusetts General Hospital · U2C · FY2025 · CA

Role of Tumor Stem Cells Recurrent Prostate Cancer

$387,762
Gary Smith · Univ Of North Carolina Chapel Hill · P01 · FY2014 · CA

Cancer Cell Intrinsic Interferon-I pathway Activation by Fractionated Radiation

$387,731
Sandra Demaria · Weill Medical Coll Of Cornell Univ · R01 · FY2017 · CA

NK cell exhaustion in metastatic melanoma

$387,731
Nina Bhardwaj · Icahn School Of Medicine At Mount Sinai · R01 · FY2018 · CA

Harnessing Csf-2 compartmentalized role on tissue resident phagocytes to uncouple anti-tumoral from pathological immunity induced by checkpoint inhibitors

$387,731
Miriam Merad · Icahn School Of Medicine At Mount Sinai · R01 · FY2015 · CA

Dectin-1 signaling drives pancreatic oncogenesis by inducing macrophage-mediated adaptive immune suppression

$387,731
George Miller · New York University School Of Medicine · R01 · FY2018 · CA

Investigating T Cell Egress via Lymphatic Vessels in Melanoma

$387,731
Amanda W. Lund · New York University School Of Medicine · R01 · FY2020 · CA

Cellular and molecular mechanism of Hippo signaling in suppressing liver tumor formation

$387,731
Yingzi Yang · Harvard Medical School · R01 · FY2021 · CA

Cellular and molecular mechanism of Hippo signaling in suppressing liver tumor formation

$387,731
Yingzi Yang · Harvard Medical School · R01 · FY2020 · CA

Harnessing Csf-2 compartmentalized role on tissue resident phagocytes to uncouple anti-tumoral from pathological immunity induced by checkpoint inhibitors

$387,731
Miriam Merad · Icahn School Of Medicine At Mount Sinai · R01 · FY2018 · CA

Potentiating Checkpoint Blockade by Cross-Priming Tumor-Reactive T cells with In Situ Vaccination

$387,731
Joshua D Brody · Icahn School Of Medicine At Mount Sinai · R37 · FY2021 · CA