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64,565 grants matching drug discovery

Optimization of methionyl-tRNA synthetase inhibitors for human African trypanosomiasis

$696,541
Erkang Fan · University Of Washington · R01 · FY2019 · AI

A phenotypic screen for osteoarthritic pain therapeutics using all-optical electrophysiology.

$696,518
Hongkang Zhang · Quiver Bioscience Inc. · R44 · FY2021 · AR

A Bioengineering Approach to Develop a Laminar 3D Cerebellar Neuronal Circuit for Modeling Human Cerebellum

$696,516
Kathleen Joyce Millen · Seattle Children'S Hospital · R01 · FY2024 · NS

Neonatal Opioid Exposure and Withdrawal: Molecular and Behavioral Consequences

$696,506
Julie A Blendy · University Of Pennsylvania · R01 · FY2022 · DA

Neonatal Opioid Exposure and Withdrawal: Molecular and Behavioral Consequences

$696,506
Julie A Blendy · University Of Pennsylvania · R01 · FY2023 · DA

Neonatal Opioid Exposure and Withdrawal: Molecular and Behavioral Consequences

$696,506
Julie A Blendy · University Of Pennsylvania · R01 · FY2024 · DA

Discovery of novel benzimidazole resistance mechanisms

$696,385
Erik Christian Andersen · Northwestern University · R01 · FY2021 · AI

Network Resource

$696,361
Sook Wah Yee · University Of California, San Francisco · U19 · FY2013 · GM

The LINCS DCIC Engagement Plan with the CFDE

$696,280
Avi Ma'ayan · Icahn School Of Medicine At Mount Sinai · OT2 · FY2022 · OD

Clinical Informatics to Advance Epidemiology and Pharmacogenetics of Serious Cutaneous Adverse Drug Reactions

$696,239
Li Zhou · Brigham And Women'S Hospital · R01 · FY2020 · AI

Novel Probes of the Kappa Opioid Receptor: Chemistry, Pharmacology, and Biology

$696,122
Laura M Bohn · Scripps Florida · R01 · FY2015 · DA

Fox COBRE Phase II Admin Core

$696,115
Joseph M Fox · University Of Delaware · P20 · FY2022 · GM

Inhibitors of protein-protein interactions

$696,075
Nadya Tarasova · Division Of Basic Sciences - Nci · ZIA · FY2022 · CA

Decoding Astrocyte Signaling in Neural Circuitry with Novel Computational Modeling and Analytical Tools

$695,922
Guoqiang Yu · Virginia Polytechnic Inst And St Univ · R01 · FY2022 · MH

Development of Kv3.1 potentiators for correcting fast-spiking-interneuron hypofunction in schizophrenia and autism spectrum disorder

$695,775
Jerod S Denton · Vanderbilt University Medical Center · R01 · FY2023 · MH

Implementing A QSP Platform to Predict and Test Drugs for Metabolic Associated Fatty Liver Disease Genetic Variants in an iPSC-cell Based Human Biomimetic Liver Microphysiology System

$695,586
Mark T. Miedel · University Of Pittsburgh At Pittsburgh · R01 · FY2024 · DK

Optimizing HIV Treatment Monitoring under Resource Constraints

$695,576
Joseph W Hogan · Brown University · R01 · FY2017 · AI

Single-cell resolution analysis of chromatin accessibility and gene expression changes in a model of drug addiction

$695,538
Francesca Telese · University Of California, San Diego · U01 · FY2021 · DA

Preclinical validation of ABHD5 as a target for treatment of obesity.

$695,461
James G Granneman · Wayne State University · R01 · FY2016 · DK

7/7 Psychiatric Genomics Consortium: Finding actionable variation

$695,417
Arpana Agrawal · Washington University · U01 · FY2016 · MH

Advancing algorithms for image-based profiling

$695,400
Anne E. Carpenter · Broad Institute, Inc. · R35 · FY2020 · GM

Advancing algorithms for image-based profiling

$695,400
Anne E. Carpenter · Broad Institute, Inc. · R35 · FY2019 · GM

Advancing algorithms for image-based profiling

$695,400
Anne E. Carpenter · Broad Institute, Inc. · R35 · FY2021 · GM

Advancing algorithms for image-based profiling

$695,400
Anne E. Carpenter · Broad Institute, Inc. · R35 · FY2018 · GM

Rational Design of antivrials targeted to HIV-1 capsid

$695,365
Asim K Debnath · New York Blood Center · R01 · FY2012 · AI