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17,828 grants matching “crispr”
Molecular genetics and population studies of the KIR and HLA gene complexes
$301,857Mary N. Carrington · Division Of Basic Sciences - Nci · ZIA · FY2021 · CA
CRISPR/Cas-directed transposition in Tn7-like elements
$301,674Joseph E Peters · Cornell University · R01 · FY2020 · GM
Genomic and functional approaches to characterize Chr1q gains in cancer
$301,500Jason Sheltzer · Yale University · R01 · FY2024 · CA
Regulation and targeting of tumor cell states and plasticity in pancreatic cancer
$301,496Srivatsan Raghavan · Dana-Farber Cancer Inst · K08 · FY2025 · CA
Regulation and targeting of tumor cell states and plasticity in pancreatic cancer
$301,496Srivatsan Raghavan · Dana-Farber Cancer Inst · K08 · FY2024 · CA
Regulation and targeting of tumor cell states and plasticity in pancreatic cancer
$301,496Srivatsan Raghavan · Dana-Farber Cancer Inst · K08 · FY2023 · CA
Targeted regulation of transcript stability through RNA methylation and intron retention
$301,400Hani Goodarzi · University Of California, San Francisco · R01 · FY2017 · GM
CRISPR/Cas-directed transposition in Tn7-like elements
$301,390Joseph E Peters · Cornell University · R01 · FY2021 · GM
Deciphering the mechanism of SHIP1 regulation in human neutrophils
$301,384Scott David Hansen · University Of Oregon · R01 · FY2022 · GM
Deciphering the mechanism of SHIP1 regulation in human neutrophils
$301,384Scott David Hansen · University Of Oregon · R01 · FY2023 · GM
Deciphering the mechanism of SHIP1 regulation in human neutrophils
$301,384Scott David Hansen · University Of Oregon · R01 · FY2025 · GM
Deciphering the mechanism of SHIP1 regulation in human neutrophils
$301,384Scott David Hansen · University Of Oregon · R01 · FY2024 · GM
Epigenetic control of vascular niche capacity to support hematopoiesis.
$301,293Bradley Wayne Blaser · Ohio State University · R01 · FY2024 · DK
A Phase 1 Adaptive Dose Escalation Study of Mycophenolate Mofetil in Combination with Temozolomide for Patients with Newly Diagnosed Glioblastoma
$301,266Atique U. Ahmed · Northwestern University At Chicago · P50 · FY2024 · CA
Defining CRISPR adaptation and interference mechanisms in E. coli
$301,259Dipali Gurudutt Sashital · Iowa State University · R01 · FY2019 · GM
CRISPR/Cas-directed transposition in Tn7-like elements
$301,077Joseph E Peters · Cornell University · R01 · FY2022 · GM
Amphetamine in adolescence disrupts frontal cortex development
$300,989Cecilia Flores · Mcgill University · R01 · FY2020 · DA
Determining the mechanism of alpha-synuclein dependent innate immune responses in the brain
$300,395John David Beckham · Ut Southwestern Medical Center · R01 · FY2025 · NS
Pou4f3 enhancers in hearing loss treatment
$300,304Litao Tao · Creighton University · P20 · FY2022 · GM
Glycome-Enhanced KnockOut (GEKO) Technology
$300,113Brian A Cobb · Case Western Reserve University · R21 · FY2015 · DE
EAGER: DNA polymerase theta and the processing of double strand breaks
$300,000Anne B Britt · University Of California-Davis · · FY2023 · BIO
Swine model of monogenic diabetes with potential implications for T1D, T2D, and double diabetes
$300,000Adrienne Leigh Watson · Recombinetics, Inc. · R43 · FY2019 · DK
EAGER: PUF-based Probe Design for Secure Access to DNA Storage
$300,000Leonidas Bleris · University Of Texas At Dallas · · FY2023 · ENG
THE CRISPR (CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS)/CAS (CRISPR-ASSOCIATED PROTEIN) SYSTEM HAS EMERGED AS A POWERFUL TOOL FOR GENOME EDITING AND GENETIC ENGINEERING DUE TO ITS SIMPLICITY, VERSATILITY AND BROAD APPLICABILITY. IN CONTRAST TO THE RAPID PROGRESS AND BROAD APPLICATIONS OF CRISPR/CAS TECHNOLOGIES IN BIOMEDICAL AND PLANT FIELDS, ONLY LIMITED CRISPR/CAS GENOME EDITING TOOLKITS HAVE BEEN TESTED AND AVAILABLE FOR PLANT PATHOGENIC FUNGI. THE OVERARCHING GOAL OF THIS PROJECT IS TO DEVELOP AND IMPROVE BIOINFORMATIC DATABASES AND CRISPR/CAS9 TOOLKITS FOR GUIDE RNA (GRNA) DESIGN AND GENOME EDITING IN PLANT PATHOGENIC FUNGI. THIS PROJECT WILL LEAD TO A SEARCHABLE DATABASE AND WEBSITE FOR FUNGAL GRNA DESIGN AND IMPROVED CRISPR/CAS9 GENOME EDITING TOOLKITS, WHICH ARE EXPECTED TO BENEFIT THE FUNGAL RESEARCH COMMUNITY AND ACCELERATE FUNCTIONAL GENOMICS ANALYSIS AND MECHANISTIC ELUCIDATION OF FUNGAL PATHOGENESIS.
$300,000The Pennsylvania State University · · FY2020 · National Institute of Food and Agriculture
BRING-SynBio: Deciphering and directing lactylation epigenetics to control macrophage immune cell phenotype
$300,000Catherine Fromen · University Of Delaware · · FY2025 · ENG