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38,696 grants matching “als”
Lay Coach-led Early Palliative Care for Underserved Advanced Cancer Caregivers
$475,263James N. Odom · University Of Alabama At Birmingham · R37 · FY2020 · CA
Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users
$475,258Michael Copenhaver · University Of Connecticut Storrs · R01 · FY2006 · DA
Using Handhelds to Help People with Motor Impairments
$475,232Brad A Myers · Carnegie Mellon University · · FY2003 · CSE
Circadian Control of Brain-peripheral Immune Response After Stroke
$475,200Elga Esposito · Massachusetts General Hospital · R01 · FY2023 · NS
Role of CREBBP missense mutations in lymphomagenesis
$475,089Laura Pasqualucci · Columbia University Health Sciences · R01 · FY2022 · CA
Role of CREBBP missense mutations in lymphomagenesis
$475,089Laura Pasqualucci · Columbia University Health Sciences · R01 · FY2025 · CA
Human genetics and molecular mechanisms of Vein of Galen aneurysmal malformation
$475,039Kristopher Kahle · Yale University · R01 · FY2020 · NS
OUR PROJECT WILL DETERMINE THE EXTENT TO WHICH THE PERENNIAL BIOENERGY CROP MISCANTHUS (MISCANTHUS × GIGANTEUS GREEF ET DEU.) IMPROVES NUTRIENT CYCLING AND ECOSYSTEM SERVICES COMPARED TO ANNUAL CROPS GROWN IN FARMED POTHOLES. POTHOLES ARE AGROECOLOGICAL 'HOT SPOTS' CHARACTERIZED BY LOW-LYING, POORLY DRAINED, SUB-FIELD REGIONS THAT ARE DISPROPORTIONATELY VULNERABLE TO POOR CROP PRODUCTION AND IMPAIRED ECOSYSTEM SERVICES (ZEDLER, 2003). ANNUAL CROPS TYPICALLY PLANTED IN POTHOLES ARE HIGHLY SUSCEPTIBLE TO EXCESS MOISTURE STRESS, WHICH LEADS TO POOR YIELDS, FINANCIAL LOSS, AND ADVERSE ENVIRONMENTAL IMPACTS (BONNER ET AL., 2016; BRANDES ET AL., 2016). AS CLIMATE PATTERNS BECOME INCREASINGLY VARIABLE, FARMED POTHOLES WILL BECOME EVEN MORE EXPOSED TO RISK (MOORE ET AL., 2014).FARMERS REQUIRE MANAGEMENT OPTIONS IN ADDITION TO ANNUAL ROW CROPS TO REDUCE VULNERABILITY AND IMPROVE THE ECOSYSTEM SERVICE PERFORMANCE ASSOCIATED WITH SENSITIVE PORTIONS OF THEIR FIELDS (MOORE ET AL., 2014; BONNER ET AL., 2016). NUMEROUS STUDIES HAVE SHOWN THAT TARGETED INTEGRATION OF PERENNIALS INTO A WORKING LANDSCAPE CAN DISPROPORTIONALLY ENHANCE ECOSYSTEM SERVICES (E.G., ZEDLER, 2003; BOODY ET AL., 2005; WALTER ET AL., 2007 ASBJORNSEN ET AL., 2014; SCHULTE ET AL., IN REVISION), BUT NONE HAVE EXPLICITLY ADDRESSED POTHOLE WETLANDS. WETLANDS ARE GENERALLY RECOGNIZED AS IMPORTANT LOCATIONS FOR HYDROLOGIC CYCLING AND THE PROVISION OF MULTIPLE ECOSYSTEM SERVICES, INCLUDING FLOOD MITIGATION, GROUNDWATER RECHARGE, WATER PURIFICATION, CARBON SEQUESTRATION, AND WILDLIFE HABITAT (E.G., BATZER ET AL., 1999; DETENBECK ET AL., 2002; GLEASON ET AL., 2004; ZEDLER AND KERCHER, 2005). WHILE THE BENEFITS OF CONNECTED WETLAND SYSTEMS ARE ACKNOWLEDGED, COMPARATIVELY LESS IS KNOWN ABOUT POTHOLES, WHICH ARE ENCLOSED DEPRESSIONS FOUND OVER A WIDE RANGE OF GEOLOGIC AREAS AND CLIMATES, PARTICULARLY THOSE IN HETEROGENOUS LANDSCAPES OF THE US MIDWEST CORN BELT. WE PROPOSE PERENNIAL BIOENERGY GRASSES AS AN INNOVATIVE HIGH RISK/HIGH REWARD LAND MANAGEMENT OPTION THAT COULD POTENTIALLY REDUCE VULNERABILITY AND IMPROVE ECOSYSTEM SERVICES IN CORN/SOYBEAN SYSTEMS BY STRATEGICALLY PLACING MORE FLOOD TOLERANT PERENNIAL BIOENERGY GRASS IN FARMED POTHOLES. WE CHOSE MISCANTHUS AS THE FOCAL PERENNIAL BIOENERGY CROP OPTION FOR THIS PROPOSAL BECAUSE OF PRIOR RESEARCH THAT SUPPORTS IMPROVED ECOSYSTEM SERVICE PERFORMANCE (TABLE 1), EXTREME MOISTURE STRESS TOLERANCE (MANN ET AL., 2013), AND MAJOR ROLE AS A CANDIDATE BIOENERGY CROP IN THE US (LANGHOLTZ ET AL., 2016; VANLOOCKE ET AL., 2017).USING A SPATIALLY EXPLICIT INTEGRATED MEASUREMENT AND MODELING APPROACH, WE PROPOSE TO TEST THE HYPOTHESIS THAT INCORPORATING THE PERENNIAL BIOENERGY CROP MISCANTHUS INTO THE RAIN-FED MIDWEST US COULD SIGNIFICANTLY INCREASE THE OUTPUT OF THREE ECOSYSTEM SERVICES COMPARED WITH THE CURRENT MANAGEMENT SYSTEM FOR THE REGION (AFRI RFA, P. 34), SPECIFICALLY BY INCREASING BIOMASS PRODUCTION, DECREASING NITRATE LEACHING, ANDIMPROVING THE GREENHOUSE GAS (GHG) BALANCE RELATIVE TO THE CURRENT CORN/SOY CROPPING SYSTEMS IN THE REGION (TABLE 1). WE PROPOSE TO TEST THIS HYPOTHESIS BY ESTABLISHING A NEW MANIPULATIVE AND REPLICATED FIELD EXPERIMENT; EXTENDING EXISTING FIELD TRIAL DATA; AND INTEGRATING ASSOCIATED DATA WITHIN AN ESTABLISHED, PROCESS-BASED AGROECOSYSTEM MODEL (INTEGRATED BIOSPHERE SIMULATOR - AGRICULTURAL VERSION (AGROIBIS; KUCHARIK ET AL., 2003; ZIPPER ET AL., 2015). WE ALSO PROPOSE TO EXTEND OUR RESEARCH TO THE PUBLIC BY INTEGRATING OUR NEW FINDINGS INTO AN EXISTING EDUCATIONAL AND OUTREACH LEARNING PLATFORM: PEOPLE IN ECOSYSTEMS/WATERSHED INTEGRATION (PEWI; CHENNAULT ET AL., 2016).
$475,000Iowa State University Of Science And Technology · · FY2018 · National Institute of Food and Agriculture
A randomized controlled trial of Friends of the Children, a long-term professional mentoring program for adolescents at risk: impacts at post-test and 2 year follow-up
$474,986Martie L. Skinner · University Of Washington · R01 · FY2023 · HD
Community Engagement Core
$474,971Monica L. Baskin · University Of Alabama At Birmingham · P50 · FY2025 · MD
Anxiety development in 5-HT1A autoreceptor knockout mice, interaction with stress
$474,965Sheryl G Beck · Children'S Hosp Of Philadelphia · RC1 · FY2010 · MH
LIM-HD/bHLH Combinatorial Code in Motoneurons
$474,901Soo-Kyung Lee · Oregon Health & Science University · R01 · FY2013 · NS
To model crossreacting T-memory of virus-infected mice
$474,874Franco Celada · New York University School Of Medicine · R01 · FY2007 · AI
Pretreatment Change in Drinking: Relationship to Treatment Outcome
$474,785Paul R Stasiewicz · State University Of New York At Buffalo · R01 · FY2018 · AA
Oncogenic Kit receptor signaling in vivo
$474,750Peter Besmer · Sloan-Kettering Inst Can Research · R01 · FY2011 · HL
Oncogenic Kit receptor signaling in vivo
$474,750Peter Besmer · Sloan-Kettering Inst Can Research · R01 · FY2009 · HL
Proteomic Profiling of CFTR Protein Interaction
$474,750John Robert Yates · Scripps Research Institute, The · R01 · FY2010 · HL
Proteomic Profiling of CFTR Protein Interaction
$474,750John Robert Yates · Scripps Research Institute, The · R01 · FY2011 · HL
Oncogenic Kit receptor signaling in vivo
$474,750Peter Besmer · Sloan-Kettering Inst Can Research · R01 · FY2010 · HL
Transgenic Probes of Active Circuits
$474,750Mark R Mayford · Scripps Research Institute, The · R01 · FY2009 · DA
Folic Acid, Parental Mutation Rates and the Risk for Neural Tube Defects
$474,669Richard H. Finnell · University Of Texas At Austin · R01 · FY2015 · HD
SMOKING CESSATION IN EMERGENCY RESPIRATORY PATIENTS
$474,632Miriam Hospital · R01 · FY2001 · HL
Structure and Dynamics of Gap Junction Channels
$474,615Mark Jay Yeager · University Of Virginia · R01 · FY2013 · HL
Hexanucleotide repeat translation in ALS and Frontotemporal Dementia
$474,565Peter K Todd · University Of Michigan At Ann Arbor · R01 · FY2017 · NS
Physician Care in Assisted Living
$474,477John G. Schumacher · University Of Maryland Baltimore County · R01 · FY2008 · AG