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10,766 grants matching checkpoint inhibitor

Pglyrp3 cooperates with Snail1 to mediate anti-tumor immune response in breast cancer

$40,465
Mathew Sebastian · University Of Florida · F30 · FY2018 · CA

Project 1: Developing Immune Checkpoint Controlled Release Biomaterials for Caner Immunotherapy

$40,348
Richard Mu · Tennessee State University · U54 · FY2021 · CA

Combining Radiation, Allogeneic Natural Killer Immunotherapy, and PD-L1 blockade in Dogs with Naturally-Occurring Melanoma

$40,288
Aryana Razmara · University Of California At Davis · F30 · FY2023 · CA

Anxa2 drives the function of immune suppressive neutrophils in lung cancer

$40,193
A. McGarry Houghton · Fred Hutchinson Cancer Research Center · R01 · FY2021 · CA

Finding the optimal balance of immunotherapy efficacy and toxicity.

$40,189
David Eric Gerber · Ut Southwestern Medical Center · U01 · FY2021 · AI

Elucidating the distinct roles of T cell-polarized microglia in glioblastoma suppression and progression

$40,186
Lizmarie Garcia-Rivera · Salk Institute For Biological Studies · F31 · FY2023 · CA

Dissecting the Role of Radiation in Regulation of MHC-I and Neoantigen Presentation

$40,139
Chang Su · Duke University · F30 · FY2023 · CA

Dissecting the roles of a novel immune-checkpoint receptor complex in driving T cell dysfunction in cancers

$40,090
Cassandra Gilmour · Cleveland Clinic Lerner Com-Cwru · F31 · FY2021 · CA

Characterizing and Overcoming MHC-I-Mediated Immune Evasion in Triple-Negative Breast Cancer

$40,064
Dina O'Connell · Univ Of North Carolina Chapel Hill · F31 · FY2024 · CA

Identification of a targeted anti-mitotic agent that degrades Myc and specifically induces cancer cell death

$40,054
Jessica Teitel · University Of Michigan At Ann Arbor · F31 · FY2023 · CA

Mechanisms of Exosome Driven Immunoregulation of Cancer Progression

$39,956
Robert H Blelloch · University Of California, San Francisco · U01 · FY2022 · CA

Development of PD-L1 Proteolysis-Targeting Chimeras (PROTACs): An Innovative Cancer Drug Discovery Route

$39,917
Demonta Coleman · Texas A&M University · F31 · FY2025 · CA

Targeting Sox10-low cells in drug-resistant melanoma

$39,915
Sean Alexander Misek · Michigan State University · F31 · FY2019 · CA

Dissecting Early Tumor Evolution to Uncover Mechanisms of Tumor Initiation and Drug Resistance

$39,801
Matthew James Ryan · University Of California, San Francisco · F31 · FY2023 · CA

Tumor Biology and Microenvironment

$39,772
Kay-Uwe Wagner · Wayne State University · P30 · FY2022 · CA

A Novel Pathway Involving ATM, PP1 and I-2

$39,764
Bo Xu · Southern Research Institute · R01 · FY2009 · ES

Uncovering interactions of the gut microbiome with the immune system in the context of immune checkpoint inhibitors

$39,650
Jennifer Chung · University Of Connecticut Sch Of Med/Dnt · F30 · FY2020 · CA

BUBR1 in the Spindle Checkpoint and Tumor Suppression

$39,500
Wei Dai · New York Medical College · R01 · FY2006 · CA

The relative impact of the Hippo and RB tumor suppressor pathways inhibition on the ovarian cancer progression

$39,492
Fatmata Sesay · Virginia Commonwealth University · F31 · FY2021 · CA

Role of MYC Family Members in Driving Chemoresistance in Small Cell Lung Cancer

$39,468
Eli Grunblatt · University Of Washington · F30 · FY2019 · CA

A Regulatory Checkpoint in the Pathogenesis of Inflammatory Arthritis

$39,404
Christian Stehlik · Cedars-Sinai Medical Center · R01 · FY2017 · AR

Development of PD-L1 Proteolysis-Targeting Chimeras (PROTACs): An Innovative Cancer Drug Discovery Route

$39,353
Demonta Coleman · Texas A&M University · F31 · FY2024 · CA

Discovery of myeloid immune features predictive of response to cancer immunotherapy in prostate cancer

$39,311
Elizabeth McCarthy · University Of California, San Francisco · F30 · FY2022 · CA

Deubiquitinases in Cell Cycle Control

$39,277
Michael James Emanuele · Univ Of North Carolina Chapel Hill · R01 · FY2023 · GM

Cancer Immunology and Immunotherapy Program

$39,235
Keith L Knutson · Mayo Clinic Rochester · P30 · FY2024 · CA