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15,273 grants matching “antimicrobial resistance”
Biorepository Core
$225,197April Bobenchik · Miriam Hospital · P20 · FY2021 · GM
The Role of Protein Interactions in Microbial Copper/Silver Resistance
$225,062Megan M. McEvoy · University Of Arizona · R01 · FY2010 · GM
TASK A10: Murine Models of Lung Infection for Antibiotic-Resistant Pseudomonas Aeruginosa
$225,044Lynn Miesel · · N01 · FY2019 · AI
Characterization of F. tularensis Virulence Genes
$225,020Karl E Klose · University Of Texas San Antonio · P01 · FY2006 · AI
SBIR Phase I: Light Emitting Antimicrobial Bandage
$225,000Alan Glowczwski · Saber Corporation · · FY2018 · TIP
Nanoscale presentation of antimicrobial peptides found at the ocular surface
$225,000Chengzhi Cai · University Of Houston · R21 · FY2010 · EY
SBIR Phase I: Innovative High Throughput Automated System for Individualized Poultry Vaccination and Recognition and Removal of Unhealthy Chicks
$225,000Ramin Karimpour · Applied Lifesciences & Systems, Llc · · FY2016 · TIP
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** BOVINE RESPIRATORY DISEASE (BRD) IS THE MOST DEVASTATING DISEASE AFFECTING U.S. CATTLE PRODUCERS. ALTHOUGH MANY ETIOLOGICAL AGENTS HAVE BEEN IMPLICATED IN BRD, A BACTERIAL INFECTION WITH THE OPPORTUNISTIC PATHOGEN MANNHEIMIA HAEMOLYTICA IS MOST OFTEN OBSERVED. ALTHOUGH MUCH RESEARCH HAS FOCUSED ON BRD, MORBIDITY AND MORTALITY HAVE NOT DECLINED IN THE PAST 45 YEARS, AND ANTIMICROBIAL RESISTANCE, ESPECIALLY IN M. HAEMOLYTICA, HAS BEEN OBSERVED. AS A RESULT, THERE IS A PRESSING NEED FOR NOVEL PREVENTATIVES. AS IT IS KNOWN THAT THE RESPIRATORY MICROBIOTA OF CALVES WITH BRD DIFFERS FROM THAT OF HEALTHY CALVES, IT IS POSSIBLE THAT PROBIOTICS FROM THE BOVINE RESPIRATORY MICROBIOTA MAY BE THE ANSWER. OUR PRELIMINARY DATA INDICATE THAT COMMENSAL CORYNEBACTERIUM FROM THE BOVINE RESPIRATORY TRACT CAN INHIBIT M. HAEMOLYTICA GROWTH IN VITRO, POTENTIALLY DUE TO THEIR ABILITY TO PRODUCE SECONDARY METABOLITES. HOWEVER, THE METABOLITES, THE MANNER OF INHIBITION, AND OTHER PROBIOTIC PROPERTIES POSSESSED BY THESE ISOLATES ARE UNKNOWN. AS A RESULT, THE OVERALL OBJECTIVE OF THIS PROJECT IS TO FURTHER CHARACTERIZE THE PROBIOTIC CAPABILITIES OF OUR COMMENSAL CORYNEBACTERIUM ISOLATES, PROVIDING VALUABLE DATA REGARDING THE ROLE WITHIN THE BOVINE RESPIRATORY MICROBIOTA, AS WELL AS THEIR POTENTIAL TO SERVE AS EFFECTIVE PROBIOTICS FOR BRD PREVENTION. THE DEVELOPMENT OF A PROBIOTIC FOR BRD PREVENTION WOULD BE HIGHLY VALUABLE AS IT WILL IMPROVE CATTLE HEALTH WHILE REDUCING ANTIMICROBIAL USAGE, INCREASING PRODUCER PROFITABILITY, AND ENSURING A SUSTAINABLE AND SAFE FOOD SUPPLY.
$225,000Division Of Agriculture Of The University Of Arkansas · · FY2024 · National Institute of Food and Agriculture
Visible light activated self-disinfecting surfaces to reduce hospital acquired infections
$225,000Jeffrey F Roeder · Sonata Scientific, Llc · R43 · FY2019 · CK
NARMS Laboratory Portal
$225,000Eric Hoffman · Ejh & Associates, Llc · U18 · FY2025 · FD
Gonococcal interactions with human polymorphonuclear leukocytes
$225,000Alison K Criss · University Of Virginia · R00 · FY2011 · TW
Electrical Biosensor for Rapid Point-of-Care Diagnosis of Urinary Tract Infections and Antibiotic Susceptibility Testing
$225,000Meike Sofia Herget · Avails Medical, Inc. · R43 · FY2016 · AI
A sample-to-answer diagnostic for neonatal blood stream infections
$225,000Alon Singer · Helixbind, Inc. · R43 · FY2015 · HD
Bone targeted antimicrobials for the treatment of diabetic foot related infections and osteomyelitis
$225,000Frank H. Ebetino · Biovinc, Llc · R43 · FY2018 · AR
NARMS Laboratory Portal
$225,000Eric Hoffman · Ejh & Associates, Llc · U18 · FY2024 · FD
The Role of Oxidative Epithelial Defenses in Influenza Infection
$225,000Balazs Rada · University Of Georgia · R21 · FY2018 · AI
Early and accurate differential diagnosis of Lyme and other tick-borne diseases by agglutination-PCR
$225,000David Seftel · Enable Biosciences, Inc. · R43 · FY2019 · AI
Gonococcal interactions with human polymorphonuclear leukocytes
$225,000Alison K Criss · University Of Virginia · R00 · FY2009 · TW
STTR Phase I: Fungal Expression of Antimicrobial Peptides for Addition to Animal Feed
$225,000Judith Pollack · Mycoinnovation · · FY2013 · TIP
Development of a Novel, Specific, and Sensitive Mass Spectrometry-Based Protein-Ligand Binding Assay to Discover Novel Beta-Lactam Antibiotics
$225,000Jian-Qiao Gu · Warp Drive Bio, Inc · R43 · FY2017 · AI
Topical Silver Sulfadiazine Formulations with Improved Efficacy and Toxicity Prof
$225,000David John Vachon · Novion Technologies, Inc. · R43 · FY2014 · GM
Site-directed spin labeling of ArnT
$225,000Medical College Of Wisconsin · R01 · FY2005 · AI
Defining a RNA repair system conserved in pathogenic bacteria
$225,000Anna C. Karls · University Of Georgia · R21 · FY2015 · AI
Engineered Intravascular Catheters for the Treatment of Bacteremia
$225,000Jun F Liang · The Trustees Of The Stevens Institute Of Technology · R21 · FY2015 · AI
SBIR Phase I: Antibacterial Nanotopography for Orthopedic Fixation Devices
$225,000Daniel J Hickey · Tyber Medical, Llc · · FY2019 · TIP