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17,828 grants matching crispr

TCR signaling strength regulated T cell differentiation during chronic viral infection

$350,000
Weiguo Cui · Northwestern University At Chicago · R56 · FY2024 · AI

AlgenML: Drug target discovery platform for transcriptional reprogramming of MYCN-driven neuroblastoma

$350,000
Chun-Hao Huang · Algen Biotechnologies Inc · R41 · FY2021 · GM

Designer Pichia Strains That Enable Difficult-To-Express Biologics Production by Addressing Limitations in Secretory Protein Expression

$350,000
Shane Byrne · Codomax Inc. · R41 · FY2024 · TR

Collaborative Research: Data-driven engineering of the yeast Kluyveromyces marxianus for enhanced protein secretion

$350,000
Ian Wheeldon · University Of California-Riverside · · FY2024 · ENG

EAGER: Development Of Functional Genetic Tools For Endoparasitoid Wasps

$350,000
Todd A Schlenke · University Of Arizona · · FY2020 · BIO

Testing Lifespan/Healthspan Pharmacological Interventions in Humanized C. elegans Knock-In Models of Dementia

$350,000
Christopher E Hopkins · Nemametrix, Inc. · R43 · FY2018 · AG

An early-intervention gene-editing therapeutic for Pulmonary Arterial Hypertension

$350,000
Vinod Jaskula-Ranga · Hunterian Medicine Llc · R43 · FY2023 · HL

Collaborative Research: Data-driven engineering of the yeast Kluyveromyces marxianus for enhanced protein secretion

$349,999
Nancy A Da Silva · University Of California-Irvine · · FY2024 · ENG

High-throughput CRISPR-based Diagnostic Assay for Coronaviruses and Other Respiratory Diseases

$349,995
Bruce W. Birren · Broad Institute, Inc. · U19 · FY2020 · AI

A multi-faceted approach to identifying K-Ras synthetic lethal relationships

$349,929
Kevin Michael Haigis · Beth Israel Deaconess Medical Center · U01 · FY2019 · CA

Modeling and targeting tumor-immune signaling interactions in tumor microenvironment

$349,875
Fuhai Li · Washington University · R01 · FY2024 · LM

Modeling and targeting tumor-immune signaling interactions in tumor microenvironment

$349,874
Fuhai Li · Washington University · R01 · FY2025 · LM

Wnt signaling in obesity-associated colorectal cancer

$349,874
Jatin Roper · Duke University · R37 · FY2024 · CA

Deciphering the function and mechanisms of lncRNA-mediated organization of nuclear compartments

$349,857
Mitchell Guttman · California Institute Of Technology · U01 · FY2019 · DA

Mays Cancer Center at UT Health SA

$349,820
Yidong Chen · University Of Texas Hlth Science Center · P30 · FY2025 · CA

A Universal Tool for Unravelling the Requirements for Clinically Relevant Cell-Cell Interactions via In Situ Phenotyping and Tagging of Live Cells

$349,816
John M Beierle · Narwhal Bio, Inc. · R43 · FY2024 · GM

In Vivo Gene Targeting to Treat Inherited Bone Disease

$349,800
David R Deyle · Mayo Clinic Rochester · R01 · FY2015 · AR

In Vivo Gene Targeting to Treat Inherited Bone Disease

$349,800
David R Deyle · Mayo Clinic Rochester · R01 · FY2017 · AR

In Vivo Gene Targeting to Treat Inherited Bone Disease

$349,800
David R Deyle · Mayo Clinic Rochester · R01 · FY2018 · AR

In Vivo Gene Targeting to Treat Inherited Bone Disease

$349,800
David R Deyle · Mayo Clinic Rochester · R01 · FY2020 · AR

Epigenetic disruptions of PBDEs during neurodevelopment

$349,791
Ramendra N Saha · University Of California, Merced · R01 · FY2020 · ES

Development and Application of New Genome Editing Tools for the Functional Investigation of Genetic Variants of Uncertain Significance

$349,781
Alexis C. Komor · University Of California, San Diego · R35 · FY2021 · GM

Molecular basis of tumor suppression by Cdk4/6 inhibition

$349,699
Seth Michael Rubin · University Of California Santa Cruz · R01 · FY2022 · CA

Investigate and inhibit microglia support of brain metastases

$349,671
Melanie Hayden Gephart · Stanford University · U54 · FY2025 · CA

Studies of Allostery between Multi-domain Proteins and Nucleic Acid Complexes

$349,363
Victor S Batista · Yale University · R01 · FY2023 · GM