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30,917 grants matching tumor microenvironment

Project 1: Elucidating the genetics and cell of origin of pancreatic cancer initiation

$417,810
Laura D Attardi · Stanford University · P01 · FY2025 · CA

Nanocage-based systemic delivery of TGFb trap for immunomodulation of brain neoplasms

$417,726
Jung Soo Suk · University Of Maryland Baltimore · R01 · FY2025 · NS

Project 3 – Stromal derived IL-6/STAT3 signaling in the development and progression of PDAC

$417,723
Michael C Ostrowski · Medical University Of South Carolina · P01 · FY2023 · CA

Mechanisms and therapeutic targeting of osteoimmune functions of RANKL in breast cancer

$417,719
Selvarangan Ponnazhagan · University Of Alabama At Birmingham · R01 · FY2025 · CA

Co-Evolution Mechanisms of Pre-Cancer-Immune Interactions in Shaping Adaptive Cytotoxicity and Myeloid-Derived Suppression

$417,691
Ken S Lau · Vanderbilt University Medical Center · U54 · FY2022 · CA

MultiOMICS mechanistic identification of predictors of HIV DNA decay, restoration of immune homeostasis and HIV specific immunity in PWH with cancer receiving Immune check point therapy

$417,652
Rafick-Pierre Sekaly · Emory University · P01 · FY2024 · AI

Role of the pro-inflammatory omental microenvironment in ovarian cancer progression

$417,604
Chi Lam Au Yeung · University Of Tx Md Anderson Can Ctr · R37 · FY2023 · CA

A Wireless Multi-function Microscope for Lifetime Imaging of the Brain Tumor Vasculome

$417,590
Arvind P Pathak · Johns Hopkins University · R01 · FY2022 · CA

A platform for multi-modal single nucleus spatial genomics for molecular tumor analysis

$417,586
Fei Chen · Broad Institute, Inc. · R33 · FY2024 · CA

Modeling and druggable-genome screening of glioblastoma invasion using regional biopsy-guided biomaterials systems

$417,577
Manish Aghi · University Of California, San Francisco · R01 · FY2019 · CA

Biophysical and Biochemical Effects of the ECM on Breast Epithelial Cells

$417,569
Celeste M Nelson · Princeton University · R01 · FY2017 · CA

Biophysical and Biochemical Effects of the ECM on Breast Epithelial Cells

$417,569
Celeste M Nelson · Princeton University · R01 · FY2018 · CA

Biophysical and Biochemical Effects of the ECM on Breast Epithelial Cells

$417,569
Celeste M Nelson · Princeton University · R01 · FY2016 · CA

CLINICAL THERAPY TRIALS

$417,566
Katherine Kurshan Matthay · Children'S Hospital Of Los Angeles · P01 · FY2012 · CA

Investigating the IL-1R Pathway in Anaplastic Large Cell Lymphoma for Targeted Therapy

$417,520
Yibin Yang · Research Inst Of Fox Chase Can Ctr · R01 · FY2021 · CA

Inhibition of Senescence to Increase Cancer Cell Death: A New Paradigm

$417,500
Hayley M. McDaid · Albert Einstein College Of Medicine, Inc · R01 · FY2017 · CA

PGE2 Regulation of Host Defense post-BMT

$417,404
Bethany B. Moore · University Of Michigan At Ann Arbor · R01 · FY2010 · AI

Translation regulation of the mesenchymal transition by the rRNA and mRNA m6A axis

$417,401
Clara Theresa Vincent · New York University School Of Medicine · R01 · FY2023 · CA

Project 1 High-order assembly of MegaTrans complexes for hormone-independent enhancer activation

$417,396
Zhijie "jason" Liu · University Of Texas Hlth Science Center · U54 · FY2018 · CA

(PQ5) Effect of HIV infection on viral and host gene expression and antitumor immunity in Kaposi Sarcoma in Africa

$417,390
Edus Houston Warren · Fred Hutchinson Cancer Research Center · R01 · FY2020 · CA

Myoepithelial cell differentiation defects in ductal carcinoma in situ (DCIS)

$417,380
Kornelia Polyak · Dana-Farber Cancer Inst · U01 · FY2013 · CA

Subcellular enzyme-instructed self-assembly for molecular anticancer nanomedicines

$417,322
Bing Xu · Brandeis University · R01 · FY2021 · CA

Role of microbial-modulated bile acid receptor signaling in breast cancer

$417,301
Liza Makowski Hayes · University Of Tennessee Health Sci Ctr · R01 · FY2020 · CA

Targeting Ischemia-Induced Dependencies on the Metabolic Stress Response in Hepatocellular Carcinoma Through Image-Guided, Locoregional Therapy

$417,256
Terence P Gade · University Of Pennsylvania · R01 · FY2022 · CA

Project 3: Analysis of intrinsic and extrinsic factors that promote prostate neuroendocrine differentiation

$417,229
Michael M. Shen · Columbia University Health Sciences · P01 · FY2024 · CA