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17,828 grants matching “crispr”
Organoid modeling to determine and reverse age-related epigenetic changes contributing to risk of colorectal cancer
$374,578Stephen B Baylin · Johns Hopkins University · R01 · FY2019 · CA
Center for Structural Biology of HIV RNA
$374,578Alice Telesnitsky · University Of Michigan At Ann Arbor · U54 · FY2023 · AI
Organoid modeling to determine and reverse age-related epigenetic changes contributing to risk of colorectal cancer
$374,578Stephen B Baylin · Johns Hopkins University · R01 · FY2020 · CA
(PQ4) - Tools for simultaneous disruption of multiple epigenetically silenced genes for studying their roles in tumorigenesis using ex vivo human and mouse colon organoid and in vivo mouse models
$374,578Hariharan Easwaran · Johns Hopkins University · R01 · FY2021 · CA
Projection-specific gene expression in resilience to chronic stress
$374,575Alfred J Robison · Michigan State University · R01 · FY2016 · MH
The translational potential of next-generation sporadic mouse and human models of ALS/FTD
$374,349Todd Jonathan Cohen · Univ Of North Carolina Chapel Hill · R61 · FY2025 · NS
Mutant p53 as actionable cancer-specific target
$374,348Ute M Moll · State University New York Stony Brook · R01 · FY2020 · CA
A Multi-Omics Approach to Discover Metabolic Critical Quality Attributes for Cardiomyocyte Biomanufacturing
$374,300Sean P Palecek · University Of Wisconsin-Madison · R01 · FY2019 · HL
CRISPR-Cas9 based treatment of dominant retinal degeneration
$374,300Edwin M Stone · University Of Iowa · R01 · FY2022 · EY
A Multi-Omics Approach to Discover Metabolic Critical Quality Attributes for Cardiomyocyte Biomanufacturing
$374,300Sean P Palecek · University Of Wisconsin-Madison · R01 · FY2020 · HL
Metabolic and p53 Targets of Cellular Respiration of Esophageal Cancer
$374,293Robert Ripley · Division Of Basic Sciences - Nci · ZIA · FY2015 · CA
Hereditary Cancer Variants of Uncertain Significance in Stem Cells
$374,293Christopher D. Heinen · University Of Connecticut Sch Of Med/Dnt · R01 · FY2019 · CA
Cross-species Analysis of Bacterial Gene Networks
$374,195Jason M. Peters · University Of Wisconsin-Madison · R35 · FY2023 · GM
CD8 T cell derived Granzyme K activates complement that drives synovial fibroblast inflammation
$374,194Michael B Brenner · Brigham And Women'S Hospital · R01 · FY2024 · AR
CRISPR-Cas-directed transposition in Tn7-like elements
$374,088Joseph E Peters · Cornell University · R35 · FY2024 · GM
Targeted aberrant signaling in CBL-mutant leukemia
$374,064Benjamin Levine Ebert · Dana-Farber Cancer Inst · P01 · FY2024 · CA
Projection-specific gene expression in resilience to chronic stress
$374,058Alfred J Robison · Michigan State University · R01 · FY2017 · MH
Dynamics of Tau protein, Amyloid beta oligomer, and APOE isoforms at the neurovascular unit
$373,973James L McGrath · University Of Rochester · R33 · FY2023 · HL
Targeting SUMO1 degradation for advanced colon cancer therapy
$373,955Anita Bellail · Indiana University Indianapolis · R01 · FY2023 · CA
The immune regulation of macrophage antibody dependent cellular phagocytosis
$373,915Adam David Hoppe · South Dakota State University · U01 · FY2022 · AI
Towards the Design of a Programmable, Isoform-Selective Proteome Editing System
$373,872Pranam Chatterjee · University Of Pennsylvania · R35 · FY2025 · GM
Discovery and therapeutic targeting of biological determinants of lung cancer health disparities
$373,775Sharon R. Pine · University Of Colorado Denver · R01 · FY2022 · CA
Targeting ferroptosis in radioresistance in lung cancer: mechanisms and preclinical translation
$373,639Boyi Gan · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA
Defining the mitochondrial metabolic regulation of systemic innate inflammation
$373,618Andrew J Monteith · University Of Tennessee Knoxville · R35 · FY2025 · GM
Epigenetic Control of Nephron Progenitor Cell Lifespan
$373,571Samir S El-Dahr · Tulane University Of Louisiana · R01 · FY2017 · DK