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38,696 grants matching “als”
WE PROPOSE TO PROVIDE PHOTOCHEMICAL MODELING SUPPORT TO ASSIST THE DYNAMICS AND CHEMISTRY OF THE SUMMER STRATOSPHERE (DCOTSS) MISSION IN ADDRESSING THREE OF THE FOUR CHEMISTRY QUESTIONS GIVEN IN SECTION 1.2.2 OF THE INVESTIGATION IMPLEMENTATION PLAN. THE DCOTSS MISSION WILL OBTAIN MEASUREMENTS OF THE CHEMICAL COMPOSITION OF THE UPPER TROPOSPHERE AND LOWER STRATOSPHERE USING INSTRUMENTS ON BOARD THE NASA ER-2 AIRCRAFT VIA A SERIES OF FLIGHTS THAT WILL OCCUR IN SUMMER 2020 AND SUMMER 2021 FROM SALINA KANSAS. DCOTSS WAS SELECTED UNDER THE NASA EARTH SYSTEM SCIENCE PATHFINDER (EESP) VENTURE-CLASS SUBORBITAL-3 (EVS-3) COMPETITION. THE THREE CHEMISTRY QUESTIONS UPON WHICH WE PROPOSE TO FOCUS OUR CONTRIBUTION TO DCOTSS ARE: SOW Q1: HOW MUCH CHLORINE FROM VERY SHORT LIVED (VSL) SOURCES IS PRESENT IN THE LOWER STRATOSPHERE OVER NORTH AMERICA IN SUMMER? SOW Q2: WHAT CHEMICAL CHANGES TAKE PLACE IN THE STRATOSPHERE DUE TO CONVECTION IN THE NORTH AMERICAN MONSOON ANTICYCLONE? SOW Q3: WHAT WILL BE THE STRATOSPHERIC CHEMICAL RESPONSE TO AN EXPLOSIVE VOLCANIC ERUPTION? WE PROPOSE TO ADDRESS THESE THREE QUESTIONS USING EXISTING PHOTOCHEMICAL STEADY STATE (PSS) BOX MODELS (E.G. SECTION 2.2 OF WALES ET AL. 2018) THAT WE HAVE DEVELOPED AND APPLIED TO DATA COLLECTED DURING NUMEROUS PRIOR NASA AIRBORNE FIELD CAMPAIGNS AS WELL AS A SUITE OF CHEMISTRYCLIMATE MODELS (CCMS) (E.G. SECTION 4.1 OF WALES ET AL. 2018) DEVELOPED BY GROUPS WITH WHICH WE MAINTAIN ACTIVE COLLABORATIONS. OF THESE CCMS WE HAVE PARTICULARLY CLOSE TIES TO THE GEOS COMPOSITION FORECAST (GEOS-CF) MODEL DEVELOPED AT THE GLOBAL MODELING AND ASSIMILATION OFFICE (GMAO) OF NASA GODDARD SPACE FLIGHT CENTER.
$532,081University Of Maryland, College Park · · FY2020 · National Aeronautics and Space Administration
Therapeutic Protein Engineering of Single-Chain Insulin Analogs
$532,042Michael Aaron Weiss · Indiana University Indianapolis · R01 · FY2022 · DK
Therapeutic Protein Engineering of Single-Chain Insulin Analogs
$531,944Michael Aaron Weiss · Indiana University Indianapolis · R01 · FY2020 · DK
The immunological mechanism of PGRNs anti-inflammatory effect - Renewal - 1
$531,588Chuanju Liu · New York University School Of Medicine · R01 · FY2022 · AR
Mechanisms of RNA and Protein Dysregulations in ALS/FTD Associated with FUS and Ubiquilin 2
$531,537Jiou Wang · Johns Hopkins University · R01 · FY2021 · NS
The adaptor protein Crk in immune responses
$531,451Dongfang Liu · Methodist Hospital Research Institute · R56 · FY2017 · AI
CAREER: Understanding the Role of Cu-Containing Secondary Phase Particles in Enhancing the Resistance to the Environmental Acceleration to Fatigue in Age-Hardenable Al Alloys
$531,450Jenifer S Locke · Ohio State University, The · · FY2020 · MPS
Protein Structure, Stability, and Amyloid Formation
$531,424Ruth Nussinov · Division Of Basic Sciences - Nci · ZIA · FY2012 · CA
Therapeutic Protein Engineering of Single-Chain Insulin Analogs
$531,394Michael Aaron Weiss · Indiana University Indianapolis · R01 · FY2021 · DK
A Systematic Dopant-selection Strategy for Advanced Manufacturing of High Strength Transparent Magnesium Aluminate Spinel
$531,383Masashi Watanabe · Lehigh University · · FY2020 · ENG
MOTOR-Maternal Oral Therapy to Reduce Obstetric Risk
$531,367Steven Nmn Offenbacher · Univ Of North Carolina Chapel Hill · U01 · FY2006 · DE
Computer-based vs Interpersonal HIV preventive intervent
$531,277Marguerita A Lightfoot · University Of California, San Francisco · R01 · FY2008 · MH
THE PHOENIX MARS SCOUT MISSION DISCOVERED SALTS THAT CAN FORM LIQUID SOLUTIONS AT MARS ENVIRONMENTAL CONDITIONS [HECHT ET AL., 2009] AND PHYSICAL AND
$531,253Regents Of The University Of Michigan · · FY2014 · National Aeronautics and Space Administration
Targeting DNA repair to eradicate TKI-refractory/resistant CML
$531,250Tomasz Skorski · Temple Univ Of The Commonwealth · R01 · FY2016 · CA
Targeting DNA repair to eradicate TKI-refractory/resistant CML
$531,250Tomasz Skorski · Temple Univ Of The Commonwealth · R01 · FY2015 · CA
Growth differentiation control in primary keratinocytes
$531,241Gian Paolo Dotto · Massachusetts General Hospital · R01 · FY2008 · AR
RAPID FLOW CYTOMETRY SCREEN FOR IDENTIFYING NOVEL ALS DRUG LEADS
$531,186The University Of Wollongong · · FY2019 · Department of the Army
Risk and Benefits of Overdose Education and Naloxone Prescribing to Heroin Users
$531,170Sandra D. Comer · New York State Psychiatric Institute Dba Research Foundation For Mental Hygiene, Inc · R01 · FY2016 · DA
RNA Surveillance and Protein Translation in FTD
$531,148Haining Zhu · University Of Arizona · R01 · FY2023 · NS
RNA Surveillance and Protein Translation in FTD
$531,148Haining Zhu · University Of Arizona · R01 · FY2024 · NS
Noninvasive Assessment of Neuromuscular Disease using Electrical Impedance
$531,082Jose Luis Bohorquez · Myolex, Inc. · R44 · FY2013 · NS
Effect of Metalloprotease Inhibition on Age-Associated Arterial Remodeling
$531,057Edward Lakatta · National Institute On Aging · ZIA · FY2018 · AG
Assembly and Peptide Cross Talk in Amyloid Systems
$531,000Michael T Bowers · University Of California-Santa Barbara · · FY2021 · MPS
Molecular mechanism of RIG-I and RIPLET in antiviral signaling
$530,998Sun Hur · Boston Children'S Hospital · R01 · FY2023 · AI
Molecular mechanism of RIG-I and RIPLET in antiviral signaling
$530,998Sun Hur · Boston Children'S Hospital · R01 · FY2022 · AI