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64,565 grants matching drug discovery

Drug discovery of COMT inhibitors to treat cognitive deficits in schizophrenia

$809,271
James Barrow · Lieber Institute, Inc. · R01 · FY2016 · MH

Discovery of Potent Selective Inhibitors of the Histone Methyltransferase SUV39H1 for the Treatment of Cancer

$809,248
Charles H Spruck · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2025 · CA

Discovery of Potent Selective Inhibitors of the Histone Methyltransferase SUV39H1 for the Treatment of Cancer

$809,234
Charles H Spruck · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2024 · CA

Development of the UValidate platform for the profiling of topically applied chemical agents.

$809,224
Peter Sykora · Amelia Technologies, Llc · R42 · FY2022 · ES

The Role of Biofilms in the Pathogenesis of Otorrhea

$809,222
Garth D. Ehrlich · Allegheny-Singer Research Institute · R01 · FY2007 · DC

Relaxivity Contrast Imaging as Biomarker of Muscle Degeneration in ALS

$809,219
Christopher Chad Quarles · St. Joseph'S Hospital And Medical Center · R61 · FY2022 · NS

Translational big data analytic approaches to advance drug repurposing for Alzheimer's disease

$809,200
Li Shen · University Of Pennsylvania · R01 · FY2021 · AG

Expansion of an efficient drug repurposing platform for rare genetic diseases.

$809,130
Christopher Gibson · Recursion Pharmaceuticals, Llc · R44 · FY2015 · TR

Open-Source Toolkit for Knowledge-Based Querying of Time-Oriented Data

$809,109
Amarendra K. Das · Stanford University · R01 · FY2010 · LM

Ligand discovery for delineating cholesterol homeostasis in the brain

$808,990
Steven H Liang · Massachusetts General Hospital · R01 · FY2021 · AG

Calcium Pump Activators for Heart Failure Therapy

$808,914
David Dale Thomas · University Of Minnesota · R01 · FY2015 · HL

The regulation of synaptic transmission and neural circuit function

$808,811
Wei Lu · National Institute Of Neurological Disorders And Stroke · ZIA · FY2012 · NS

Molecular Chemiluminescence Probes for Imaging of Amyloid beta in Animal Models

$808,786
Chongzhao Ran · Massachusetts General Hospital · R01 · FY2025 · AG

Lead optimization of novel ML-IAP antagonists to treat lung cancer

$808,701
Nicholas David Cosford · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2016 · CA

Targeting the Genus Leishmania with Small Molecules

$808,549
Scott Edward Schaus · Boston University (Charles River Campus) · R01 · FY2021 · AI

MSHS Translational Science Hub

$808,544
Alan J Moskowitz · Icahn School Of Medicine At Mount Sinai · KL2 · FY2016 · TR

HIGH THROUGHPUT PROTEIN-PROTEIN INTERACTION INTERROGATION IN CANCER

$808,473
Haian Fu · Emory University · U01 · FY2013 · CA

High Throughput Protein-Protein Interaction Interrogation in Cancer

$808,473
Haian Fu · Emory University · U01 · FY2013 · CA

Structural bioinformatics software for epitope selection and antibody engineering

$808,267
Steven Joseph Darnell · Dnastar, Inc. · R44 · FY2015 · GM

Detection, prevention and treatment of acute myeloid leukemia (AML) relapse.

$808,122
Christopher Hourigan · National Heart, Lung, And Blood Institute · ZIA · FY2013 · HL

Mechanisms of FGF Receptor Regulation and Signaling

$807,903
Moosa Mohammadi · New York University School Of Medicine · R01 · FY2013 · DE

Pediatric toxicity and efficacy in long-term systemic treatment with anti-sense

$807,794
John N Van Den Anker · Children'S Research Institute · U54 · FY2015 · HD

Pediatric toxicity and efficacy in long-term systemic treatment with anti-sense

$807,792
John N Van Den Anker · Children'S Research Institute · U54 · FY2012 · HD

Discovery of Phospopantetheinyl Transferse Inhibitors Against Mycobacterium tuberculosis

$807,677
Jeffrey Aube · Univ Of North Carolina Chapel Hill · R01 · FY2021 · AI

High Content Screening for Bifunctional Chimera Biologics

$807,664
Liz Valente · Heligenics Inc · R44 · FY2025 · AI