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51,593 grants matching hepatitis

Drug Resistance in HCV NS3/4A - Inhibitor binding versus substrate recognition

$588,464
Celia A. Schiffer · Univ Of Massachusetts Med Sch Worcester · R01 · FY2018 · AI

Drug Resistance in HCV NS3/4A - Inhibitor binding versus substrate recognition

$588,464
Celia A. Schiffer · Univ Of Massachusetts Med Sch Worcester · R01 · FY2017 · AI

EASTERN COOPERATIVE ONCOLOGY GROUP - WISCONSIN STUDIES

$588,460
James A Stewart · University Of Wisconsin-Madison · U10 · FY2007 · CA

HBV-specific T cell immunity in HBV/HIV coinfection

$588,450
Michael Jeffrey Vinikoor · University Of Alabama At Birmingham · R37 · FY2025 · AI

Amphiphilic Polycations for Nucleic Acid Delivery

$588,373
David B Rozema · Mirus Bio Corporation · R44 · FY2007 · GM

Targeting the Metabolic Basis of Cachexia in Pancreatic Cancer

$588,368
Pankaj Kumar Singh · University Of Nebraska Medical Center · R01 · FY2019 · CA

MOLECULAR BEACONS FOR RETROVIRAL DIAGNOSTICS

$588,336
Public Health Research Institute · R01 · FY2002 · EB

Coaching Performance Driven Practice Change in the Context of Value Based Purchasing Under New York Medicaid

$588,310
Charles J Neighbors · New York University School Of Medicine · R33 · FY2023 · DA

Role of extracellular vesicles in the regulation of immunometabolism in obesity

$588,256
Takahisa Nakamura · Cincinnati Childrens Hosp Med Ctr · R01 · FY2022 · DK

Enhanced Anti-HIV-1 Antibody Responses in African American Women Seropositive for

$588,205
Phillip Berman · University Of California Santa Cruz · R01 · FY2015 · DA

MRI-based Quantitative Susceptibility Mapping of Hepatic Iron Overload

$588,177
Diego Hernando · University Of Wisconsin-Madison · R01 · FY2019 · DK

A Network &Dyad HIV Prevention Intervention for IDUs

$588,114
Johns Hopkins University · R01 · FY2003 · DA

Role of the Endothelium and Neutrophils in the Prothrombotic Nature of HIT

$588,104
Mortimer Poncz · Children'S Hosp Of Philadelphia · R01 · FY2018 · HL

THERE HAS BEEN A GROWING APPRECIATION FOR THE BENEFITS OF USING NON-THERMAL TREATMENTS AS GREENER AND MORE ENERGY EFFICIENT PROCESSES FOR THE TREATMENT OF BEVERAGES WHEN COMPARED TO THERMAL TREATMENTS. AS A RESULT, THERE IS AN INCREASED INTEREST IN APPLYING ULTRAVIOLET (UV) LIGHT TECHNOLOGY IN THE TREATMENT OF BEVERAGES TO INACTIVATE BACTERIAL SPORES AND RESISTANT NON-ENVELOPED VIRUSES SUCH AS HEPATITIS A VIRUS (HAV) AND HUMAN NOROVIRUSES (HNOV), IN ADDITION TO PATHOGENIC AND SPOILAGE MICROORGANISMS. THIS PROJECT IS INTENDED TO ACHIEVE THESE GOALS AND BRIDGE EXISTING KNOWLEDGE GAPS BY ASSESSING THE SENSITIVITY OF TARGET FOODBORNE VIRUSES AND BACTERIAL SPORES TO UV AND DEVELOPING DOSE-RESPONSE CURVES (PASTEURIZED EQUIVALENT DOSE OR STERILIZED EQUIVALENT DOSE). RECENT PUBLISHED STUDIES HAVE DEMONSTRATED A HIGH RESISTANCE OF THESE ORGANISMS TO THERMAL PROCESSING, AND UV COULD BE AN IMPORTANT COMPLEMENTARY TREATMENT. THIS PROPOSAL IS TARGETED TO DEVELOP EMERGING FOODBORNE VIRAL PATHOGEN DISINFECTION METHODS FOR BEVERAGE TREATMENT AS WELL AS SPORE INACTIVATION. SYSTEMS DEVELOPED IN THIS PROJECT WILL BE A BREAKTHROUGH IN CURRENT PASTEURIZATION AND STERILIZATION PRACTICES FOR LIQUID FOODS IN THE UNITED STATES AND ARE LIKELY TO EXTEND TO FINDING SOLUTIONS FOR GLOBAL FOOD SAFETY ISSUES. THE PROJECT ALSO INTENDS TO ASSESS CONSUMER PERCEPTIONS AND ACCEPTANCE OF NON-THERMAL UV TECHNOLOGIES AND TO DEVELOP EDUCATIONAL PROGRAMMING FOR CONSUMERS BASED UPON SURVEY RESULTS. IN ADDITION, INTENSE EDUCATIONAL PROGRAMS FOR STUDENTS AT THE GRADUATE AND UNDER-GRADUATE LEVELS WILL BE IMPLEMENTED, AND EDUCATIONAL WORKSHOPS ON NEW FOOD SAFETY TECHNOLOGIES WILL BE HELD FOR FOOD SAFETY PROFESSIONALS AND EDUCATORS.

$588,085
Tennessee State University · · FY2019 · National Institute of Food and Agriculture

3/3 COMpAAAS Tripartite: ART-CC, KP, and VA

$587,980
Amy Caroline Justice · Yale University · U01 · FY2017 · AA

Conceptual and mechanistic insights into the development of diet-induced obesity through disruption of hepatic circadian rhythms by the gut microbiome

$587,960
Eugene B Chang · University Of Chicago · R01 · FY2021 · DK

Conceptual and mechanistic insights into the development of diet-induced obesity through disruption of hepatic circadian rhythms by the gut microbiome

$587,960
Eugene B Chang · University Of Chicago · R01 · FY2022 · DK

Conceptual and mechanistic insights into the development of diet-induced obesity through disruption of hepatic circadian rhythms by the gut microbiome

$587,960
Eugene B Chang · University Of Chicago · R01 · FY2020 · DK

Novel strategies to accelerate repair of drug-induced hepatotoxicity

$587,852
James P Luyendyk · Michigan State University · R01 · FY2023 · DK

Vaccine and Treatment Evaluation Unit at Saint Louis University

$587,832
Daniel F. Hoft · Saint Louis University · UM1 · FY2022 · AI

Ethanol Effects on the Transcriptional Regulatory Network in Liver Regeneration

$587,815
Joannes B Hoek · Thomas Jefferson University · R01 · FY2018 · AA

Orally Active Nucleoside Phosphonates for Hepatitis C Virus

$587,665
Robert Turner Schooley · University Of California, San Diego · R01 · FY2011 · AI

Tesamorelin Effects on Liver Fat and Histology in HIV: A Collaborative U01 Grant

$587,655
Steven Kyle Grinspoon · Massachusetts General Hospital · U01 · FY2015 · AI

Project 2: PREVENT Preclinical safety and efficacy studies

$587,628
Kenneth E Palmer · University Of Louisville · U19 · FY2014 · AI

Enhanced Anti-HIV-1 Antibody Responses in African American Women Seropositive for

$587,526
Phillip Berman · University Of California Santa Cruz · R01 · FY2016 · DA