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30,917 grants matching tumor microenvironment

Chitinase-3-like-1 mediated immunosuppression in Glioblastoma

$462,773
Baoli Hu · University Of Pittsburgh At Pittsburgh · R01 · FY2024 · CA

Optimizing antibody-based therapy through a system platform of pharmacokinetics-pharmacodynamics-immunodynamics

$462,763
Yanguang Cao · Univ Of North Carolina Chapel Hill · R35 · FY2018 · GM

Targeting ferroptosis in aggressive subtypes of lung cancer

$462,704
Triparna Sen · Ohio State University · R01 · FY2025 · CA

Engineered hybrid aging model for disease progression

$462,702
Pinar Zorlutuna · University Of Notre Dame · R01 · FY2025 · CA

Modeling immunity with a hybrid lymph node tissue-chip

$462,626
Rebecca R Pompano · University Of Virginia · R01 · FY2020 · AI

Interactions between the tumor cells and the neuro-immune microenvironment in mutant IDH1 gliomas: implications for therapeutics

$462,618
Maria G Castro · University Of Michigan At Ann Arbor · R01 · FY2018 · NS

Mechanisms and Vulnerabilities of SWI/SNF chromatin remodeling complex mutant lung cancer

$462,600
Yonathan Lissanu · University Of Tx Md Anderson Can Ctr · R37 · FY2023 · CA

Project 3

$462,573
Charles J Rosser · Cedars-Sinai Medical Center · U54 · FY2022 · CA

Defining epigenetic signaling to reshape pancreatic tumor microenvironment

$462,567
Jiaqi Shi · University Of Michigan At Ann Arbor · R37 · FY2022 · CA

Project 3: Development of Strategies to Deplete Myelofibrosis Stem Cells

$462,546
Ronald Hoffman · Icahn School Of Medicine At Mount Sinai · P01 · FY2025 · CA

High-throughput palmitoyl-proteomics profiling of extracellular vesicles for identification of biomarkers for early detection of clinically significant prostate cancer

$462,518
Dolores Di Vizio · Cedars-Sinai Medical Center · R01 · FY2017 · CA

Training in Cellular & Molecular Mechanisms of Tumor Rejection

$462,505
Olivera J Finn · University Of Pittsburgh At Pittsburgh · T32 · FY2011 · CA

Function of IL35+ B cells in pancreatic cancer

$462,460
Yuliya Pylayeva-Gupta · Univ Of North Carolina Chapel Hill · R37 · FY2019 · CA

Targeting the EGFR-PI3K/mTOR Signaling Circuitry: A Network-Based Approach for Oral Cancer Precision Therapy

$462,426
J. Silvio Gutkind · University Of California, San Diego · R01 · FY2022 · DE

Mechanical Regulation of Tumor Angiogenesis

$462,422
Cynthia A Reinhart-King · Vanderbilt University · R01 · FY2019 · HL

Personalization and Failure Testing of Dual Switch Gene Drives in Lung Cancer

$462,419
Justin Pritchard · Pennsylvania State University, The · U01 · FY2021 · CA

Fatty acid signaling in the pancreatic tumor microenvironment

$462,414
Mara H. Sherman · Sloan-Kettering Inst Can Research · R01 · FY2024 · CA

Targeting Stromal Influences on Glutamine Addiction in Ovarian Cancer

$462,390
Deepak Nagrath · University Of Michigan At Ann Arbor · R01 · FY2022 · CA

Chemical Exchange Saturation Transfer (CEST) MRI for the Characterization Small Renal Masses

$462,317
Elena Vinogradov · Ut Southwestern Medical Center · R01 · FY2023 · CA

Discovery of novel PCFT-targeted agents

$462,299
Larry H. Matherly · Wayne State University · R01 · FY2011 · CA

Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer

$462,269
Donald W. Kufe · Dana-Farber Cancer Inst · R01 · FY2025 · CA

Targeting innate immune pathways in breast cancers with chromosomal instability

$462,250
Samuel F Bakhoum · Sloan-Kettering Inst Can Research · P50 · FY2023 · CA

Targeting innate immune pathways in breast cancers with chromosomal instability

$462,250
Samuel F Bakhoum · Sloan-Kettering Inst Can Research · P50 · FY2021 · CA

Defining metabolic adaptations within the PDAC "arid" tumor microenvironment

$462,168
Chi V. Dang · Johns Hopkins University · R01 · FY2022 · CA

Understanding the induction of T cell dysfunction in the context of lung cancer

$462,141
Stefani Spranger · Massachusetts Institute Of Technology · R37 · FY2025 · CA