Sort
17,828 grants matching “crispr”
KSHV alteration of cellular metabolism
$407,928Michael Lagunoff · University Of Washington · R01 · FY2024 · CA
Employing novel humanized murine strains to develop hematopoietic stem cell gene therapeutic approaches for very early-onset inflammatory bowel disease due to IL10-receptor deficiency.
$407,902Scott B Snapper · Boston Children'S Hospital · R56 · FY2017 · AI
Targeting neuroblastoma cell state plasticity
$407,872Kimberly Stegmaier · Children'S Hosp Of Philadelphia · P01 · FY2025 · CA
Glial roles in experience-dependent critical period remodeling
$407,869Kendal Broadie · Vanderbilt University · R01 · FY2025 · NS
Glial roles in experience-dependent critical period remodeling
$407,869Kendal Broadie · Vanderbilt University · R01 · FY2024 · NS
Investigating Max as a tumor suppressor gene in small cell lung cancer and other neuroendocrine tumors
$407,812Robert Neil Eisenman · Fred Hutchinson Cancer Research Center · R01 · FY2021 · CA
The Metabolic Pathogenesis of Chromophobe Renal Cell Carcinoma
$407,775Elizabeth P Henske · Brigham And Women'S Hospital · R01 · FY2021 · CA
Cancer Biology in the Zebrafish
$407,763Leonard I Zon · Boston Children'S Hospital · R01 · FY2019 · CA
Role of the soluble (pro)renin receptor in blood pressure regulation
$407,716Nirupama Ramkumar · University Of Utah · R56 · FY2021 · HL
Intersection of autophagy and vesicle trafficking in Her2-positive breast cancer
$407,633Jun-Lin Guan · University Of Cincinnati · R01 · FY2025 · CA
Intersection of autophagy and vesicle trafficking in Her2-positive breast cancer
$407,633Jun-Lin Guan · University Of Cincinnati · R01 · FY2023 · CA
Beyond ephrins: unbiased discovery of novel signaling pathways regulating topographic map formation and maturation in vivo.
$407,545Fabienne Emmanuelle Poulain · University Of South Carolina At Columbia · R21 · FY2021 · NS
The role of the CD58:CD2 axis in cancer immune evasion and resistance to immunotherapy
$407,530Benjamin Izar · Columbia University Health Sciences · R01 · FY2022 · CA
Regulation of retrotransposable element activity in cellular senescence and aging.
$407,462John M. Sedivy · Brown University · P01 · FY2016 · AG
Project 1: Role of the H3K27 demethylase KDM6A in bladder cancer pathogenesis
$407,405David B. Solit · Columbia University Health Sciences · P01 · FY2018 · CA
Mechanism of Action of Prion Protein-Lowering Small Molecules
$407,400Sonia Minikel Vallabh · Broad Institute, Inc. · R01 · FY2024 · NS
Epigenetic Regulation of Human Telomeres
$407,400Paul M. Lieberman · Wistar Institute · R01 · FY2019 · CA
Exploiting metabolic vulnerabilities of CD4 T cell subsets to control inflammatory disease
$407,341Jeffrey C Rathmell · Vanderbilt University Medical Center · R01 · FY2023 · DK
Combining protein and DNA engineering to create bioswitches
$407,221Stewart N Loh · Upstate Medical University · R01 · FY2023 · GM
Organoid modeling to determine and reverse age-related epigenetic changes contributing to risk of colorectal cancer
$407,205Stephen B Baylin · Johns Hopkins University · R01 · FY2023 · CA
Organoid modeling to determine and reverse age-related epigenetic changes contributing to risk of colorectal cancer
$407,205Stephen B Baylin · Johns Hopkins University · R01 · FY2022 · CA
Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers
$407,025Sidi Chen · Yale University · R33 · FY2019 · CA
Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers
$407,025Sidi Chen · Yale University · R33 · FY2021 · CA
Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers
$407,023Sidi Chen · Yale University · R33 · FY2020 · CA
Molecular Mechanisms of Hair Bundle Development and Maintenance
$406,951Jonathan Edward Bird · University Of Florida · R01 · FY2022 · DC