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10,766 grants matching checkpoint inhibitor

SBIR Phase I: Anti-Tumor Immune Redirectors (AIRs) for cancer treatment

$225,000
Joshua Wang · Pathovax · · FY2018 · TIP

Predevelopment of VV2003, a Novel CRAC Channel Inhibitor, to Improve Outcomes Associated with Checkpoint Inhibitor Immunotherapy

$225,000
Milton L Greenberg · Vivreon Biosciences, Llc · R43 · FY2018 · CA

Small-molecule agonists of the RIG-I-like receptor pathway as cancer immunotherapeutics

$225,000
Peter Probst · Kineta, Inc. · R43 · FY2018 · CA

Co-targeting Ezh2 with PD1 to improve T cell exhaustion reversal and tumor responses

$225,000
Mumtaz Yaseen Balkhi · It Bio, Llc · R43 · FY2019 · CA

Small molecule ubiquitin ligase modulators for immunotherapy of cancer

$224,995
Kumar Suresh · Progenra, Inc. · R43 · FY2017 · CA

Targeting TGF-beta activation in tumors

$224,981
Bo Yu · Larix Bioscience, Llc · R43 · FY2019 · CA

Novel monobody therapy for pancreatic cancer

$224,981
Bo Yu · Larix Bioscience, Llc · R43 · FY2017 · CA

Predevelopment of VV2003, a Novel CRAC Channel Inhibitor, to Improve Outcomes Associated with Checkpoint Inhibitor Immunotherapy

$224,700
Milton L Greenberg · Vivreon Biosciences, Llc · R44 · FY2020 · CA

RAPAMYCIN BLOCKADE OF PROTEIN PHOSPHATASE SIGNALING

$224,588
University Of Virginia Charlottesville · R01 · FY2003 · CA

RAPAMYCIN BLOCKADE OF PROTEIN PHOSPHATASE SIGNALING

$224,571
University Of Virginia Charlottesville · R01 · FY2004 · CA

Reversible vitamin A-dependent arrest of spermatogonia

$224,547
James K Tsuruta · Univ Of North Carolina Chapel Hill · R01 · FY2006 · HD

SBIR Phase I: Highly Specific Flex-Hinge Antibody-Like Checkpoint Inhibitors for Safer and More Effective Cancer Therapy

$224,455
Daniel J Capon · Hinge Bio, Inc. · · FY2018 · TIP

Special Public T Cell Receptor Sequences that Predict Outcomes for Cancer Patients

$224,400
Seth M Pollack · Northwestern University At Chicago · R21 · FY2023 · CA

(PQ6): Is Adrenergic Stress-induced Immune Suppression at the Crossroads of Circadian Rhythm Disruption and Cancer?

$224,199
Elizabeth Repasky · Roswell Park Cancer Institute Corp · R21 · FY2018 · CA

Specificity of the Ubiquitin System in Lymphoid Malignancies

$224,099
Luca Busino · University Of Pennsylvania · R00 · FY2014 · CA

NAAA Inhibitors for pain and inflammation

$223,903
Roger Heim · Anteana Therapeutics, Inc. · R43 · FY2015 · NS

Highly Multiplexed Analysis of Solid Tumors and Liquid Tissues by Cyclic Immunofluorescence

$223,840
Eric Kaldjian · Rarecyte, Inc. · R41 · FY2018 · CA

P3: Molecular Mechanisms Underlying Therapy Response to Radiation and Immune Checkpoint BlockadeýSUBAWARD

$223,801
David Sung-Wen Yu · Cleveland Clinic Lerner Com-Cwru · U54 · FY2025 · CA

Nitrosourea-induced growth arrest and apoptotic pathways

$223,778
Kevin D Brown · University Of Florida · R01 · FY2006 · CA

Cell-based assay directly monitoring RNA Polymerase I activity for cancer drug discovery

$223,700
Ryan O'Hanlon · Lucerna, Inc. · R43 · FY2020 · CA

Genomics Core

$223,652
Jaroslav Jelinek · Coriell Institute For Medical Research · P50 · FY2021 · CA

INTERACTION OF YEAST CHECKPOINT PROTEINS AS DRUG ASSAY

$223,650
University Of North Texas Hlth Sci Ctr · R01 · FY2004 · CA

Delivering miR-29a to enhance anti-viral and anti-tumor responses in vivo

$223,343
Erietta Stelekati · University Of Miami School Of Medicine · R21 · FY2025 · AI

A Phase 1 Clinical Trial Evaluating the Novel Small Molecule Immuno-Oncology Antagonist SX-682 Alone and With Pembrolizumab in Metastatic Melanoma

$223,334
Stuart J Kahn · Syntrix Biosystems, Inc. · R44 · FY2020 · CA

IGF::OT::IGF SBIR PHASE I TOPIC 354-A NOVEL PREDICTIVE TEST FOR RESPONSE TO IMMUNOTHERAPIES FOR PATIENTS WITH NON-SMALL CELL LUNG CANCER; POP 09/19/16-06/18/17

$223,063
Greg Bertenshaw · Biomarker Strategies, Llc · N43 · FY2016 · CA