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17,054 grants matching genome editing

Development, Optimization and Preclinical Modeling of Hematopoietic Stem Cell Gene Editing for the Treatment of RAG1 Immunodeficiency

$441,100
Pietro Genovese · Dana-Farber Cancer Inst · R01 · FY2022 · AI

Role of a dual splicing and amino acid code in myopia, cone dysfunction and cone dystrophy associated with L/M opsin interchange mutations

$440,938
Maureen E Neitz · University Of Washington · R01 · FY2019 · EY

CORE 2: Technology Core

$440,831
Alexander Marson · University Of California, San Francisco · U19 · FY2019 · AI

Structural bases of high fidelity of DNA polymerase delta

$440,823
Aneel K. Aggarwal · Icahn School Of Medicine At Mount Sinai · R01 · FY2010 · CA

Translational Core (Expression Core)

$440,821
Vijay K Kuchroo · University Of Pittsburgh At Pittsburgh · P01 · FY2022 · AI

Translational Core (Expression Core)

$440,821
Vijay K Kuchroo · University Of Pittsburgh At Pittsburgh · P01 · FY2019 · AI

Translational Core (Expression Core)

$440,820
Vijay K Kuchroo · University Of Pittsburgh At Pittsburgh · P01 · FY2020 · AI

Translational Core (Expression Core)

$440,820
Vijay K Kuchroo · University Of Pittsburgh At Pittsburgh · P01 · FY2021 · AI

Improving Xenogeneic Chimerism and Tolerance through Genome Engineering Technology

$440,787
George M Church · Columbia University Health Sciences · P01 · FY2016 · AI

Molecular Mechanisms of Dystrophin Expression in Ameliorated Phenotypes

$440,738
Kevin M Flanigan · Research Inst Nationwide Children'S Hosp · R01 · FY2024 · NS

Systematic characterization of cancer variants using single-cell functional genomics

$440,728
Thomas Maxwell Norman · Sloan-Kettering Inst Can Research · R33 · FY2022 · CA

The basis for and function of enteroendocrine lineage plasticity in the intestinal DNA damage response

$440,575
Christopher Joachim Lengner · University Of Pennsylvania · R01 · FY2021 · DK

Experimental Integration, Design and Analysis Core

$440,562
Janet L Stein · University Of Vermont & St Agric College · P01 · FY2023 · CA

Project 3: Role of CTCF in HTLV-1 Replication and Transformation

$440,485
Lee Ratner · Ohio State University · P01 · FY2023 · CA

Systematic discovery of Olig2 upstream regulators for central nervous system myelination

$440,275
Yungki Park · State University Of New York At Buffalo · R21 · FY2025 · NS

Targeted regulation of transcript stability through RNA methylation and intron retention

$440,256
Hani Goodarzi · University Of California, San Francisco · R01 · FY2020 · GM

Development of lariat-shaped caged morpholinos for optochemical gene regulation

$440,039
James K Chen · Stanford University · R01 · FY2014 · GM

Function of the METTL3-NUP93 complex-mediated nuclear export of m6A-modified mRNAs in castration-resistant prostate cancer.

$439,997
Kexin Xu · University Of Texas Hlth Science Center · R01 · FY2024 · CA

Endonuclease-mediated disruption of latent HSV as curative therapy

$439,988
Keith R Jerome · Fred Hutchinson Cancer Research Center · R01 · FY2020 · AI

Coordination of ATR Signaling for Genetic Quality Control, Silencing, and DNA Repair During Meiosis

$439,848
Robert S Weiss · Cornell University · R01 · FY2018 · HD

Single cell modeling of cancer mutations

$439,841
Hanlee Ji · Stanford University · R33 · FY2024 · CA

Dissecting and Targeting RB1-Mutant Osteosarcoma

$439,831
Dung-Fang Lee · University Of Texas Hlth Sci Ctr Houston · R01 · FY2021 · CA

Project 3 Topological mapping of chromatin architectures for hormone-independent gene transcription

$439,821
Victor Jin · University Of Texas Hlth Science Center · U54 · FY2018 · CA

Control of adipose function through a PRDM16/Type 1 Interferon Axis

$439,809
Patrick Seale · University Of Pennsylvania · R01 · FY2016 · DK

MYC as a Biomarker in Aggressive Non-Hodgkin Lymphoma

$439,795
Yong Li · Cleveland Clinic Lerner Com-Cwru · R01 · FY2016 · CA