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64,565 grants matching “drug discovery”
Next generation free energy perturbation (FEP) calculations--enabled by a novel integration of quantum mechanics (QM) with molecular dynamics allowing a large QM region and no sampling compromises
$994,097David A Pearlman · Quantum Simulation Technologies, Inc. · R44 · FY2025 · GM
Molecular Targets COBRE
$994,005Donald M Miller · University Of Louisville · P20 · FY2009 · RR
Novel Therapeutic Strategies Targeting Re-emerging Alphaviruses
$993,983Daniel N Streblow · University Of Alabama At Birmingham · U19 · FY2016 · AI
Discovery of B. pseudomallei therapeutics for Biodefense
$993,879Donald T Moir · Microbiotix, Inc · R44 · FY2006 · AI
Advancing a novel potent Zika virus specific nucleoside analog to the clinic
$993,605Klaus Klumpp · Riboscience, Llc · R44 · FY2017 · AI
Midwest Developmental Center for AIDS Research (D-CFAR)
$993,578Elvin H. Geng · Washington University · P30 · FY2025 · AI
A high-throughput platform for crystallography-based fragment screening
$993,537Ashley M. Deacon · Accelero Biostructures, Inc. · R44 · FY2018 · GM
Microphysiological systems to model vascular malformations
$993,445Christopher C. W. Hughes · University Of California-Irvine · UG3 · FY2017 · HL
Development of the NephroPlate: A high-throughput kidney-on-a-chip platform for identifying chronic kidney disease therapies
$993,146Morgan Chandler · Mimetas Us, Inc. · R44 · FY2023 · DK
Non-Clinical Pharmacology of CX-01
$992,960Galina Vid · Ceramedix Holding, Llc · R44 · FY2025 · AI
Developing novel LOX inhibitors to target chemotherapy resistant TNBC
$992,932Ozgur Sahin · Loxigen, Inc. · R42 · FY2024 · CA
The Development of a Web-based Data Retrieval System for HIV Therapy Guidance
$992,666Colombe Chappey · Monogram Biosciences, Inc. · R44 · FY2007 · AI
Genital Herpes Vaccine Discovery
$992,626Gary Fujii · Molecular Express, Inc. · R44 · FY2008 · AI
Core G: Computation
$992,467John A Gerlt · University Of Illinois At Urbana-Champaign · U54 · FY2012 · GM
Core G: Computation
$992,467John A Gerlt · University Of Illinois At Urbana-Champaign · U54 · FY2011 · GM
Bay Area Cancer Target Discovery and Development
$992,465Michael T McManus · University Of California, San Francisco · U01 · FY2025 · CA
Systems Biology based Proteogenomic Translator for Cancer Marker Discovery towards Precision Medicine
$992,364Pei Wang · Icahn School Of Medicine At Mount Sinai · U24 · FY2018 · CA
Parent Project - Main Theme (MAIN)
$992,348Mark J Ratain · University Of Chicago · U01 · FY2012 · GM
InflammaGut: a drug-screenable co-culture system using gut-associated lymphocytes and autologous primary human gut epithelium that reports inflammation
$992,302Bill Thelin · Altis Biosystems, Inc. · R44 · FY2022 · TR
Preclinical development of a potent D-peptide RSV inhibitor
$992,263Brett D Welch · Navigen, Inc. · R44 · FY2016 · AI
Agonists of the RIG-I Innate Immune Pathway
$992,047Shawn Patrick Iadonato · Kineta, Inc. · R44 · FY2011 · AI
KL4 Surfactant to Mitigate Radiation-Induced Lung Injury
$992,017Robert Segal · Discovery Laboratories, Inc. · R44 · FY2015 · AI
Targeting the checkpoint regulator VISTA for treatment of inflammatory disease
$991,804Jay L Rothstein · Immunext, Inc. · R44 · FY2017 · AI
MIN-REACH Research Evaluation and Commercialization Hub
$991,667Vadim J. Gurvich · University Of Minnesota · U01 · FY2017 · HL
Washington Entrepreneurial Research Evaluation and Commercialization Hub
$991,450Rodney J.y. Ho · University Of Washington · U01 · FY2019 · HL