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17,828 grants matching crispr

Dissecting the impact of senescence pathways on the cellular pathogenesis of Alzheimer's disease

$460,625
Hong Zhang · Univ Of Massachusetts Med Sch Worcester · R21 · FY2024 · AG

Decoding cis-regulatory element activity through deep learning frameworks

$460,625
Jill Elizabeth Moore · Univ Of Massachusetts Med Sch Worcester · R35 · FY2025 · GM

Modeling Aneuploidy-Driven Phenotypes Across Tissues

$460,625
Emma V. Watson · Univ Of Massachusetts Med Sch Worcester · R35 · FY2025 · GM

Investigating the Roles of the Deubiquitylation Pathway in TDP-43 Pathology in ALS/FTD

$460,625
Fen-Biao Gao · Univ Of Massachusetts Med Sch Worcester · R21 · FY2025 · NS

Investigating the heterogeneity of glucose transport in lung adenocarcinoma

$460,583
Claudio Scafoglio · University Of California Los Angeles · R01 · FY2023 · CA

Elucidating the 3-D epigenetic determinants of activity-dependent gene expression in mammalian neurons

$460,505
Jennifer Elizabeth Phillips-Cremins · University Of Pennsylvania · R01 · FY2021 · NS

Defining Strategies to Target Energy Failure in Metabolically Vulnerable Human Cells

$460,375
Ken Nakamura · J. David Gladstone Institutes · R01 · FY2022 · AG

Developing programmable RNA writing tools with the novel RNA-guided RNA-targeting CRISPR effector Cas7-11

$460,261
Jonathan Samuel Gootenberg · Beth Israel Deaconess Medical Center · R01 · FY2024 · GM

Elucidating the 3-D epigenetic determinants of activity-dependent gene expression in mammalian neurons

$460,091
Jennifer Elizabeth Phillips-Cremins · University Of Pennsylvania · R01 · FY2022 · NS

APOBEC3 Proteins in HIV Restriction

$460,050
Reuben S Harris · University Of Texas Hlth Science Center · R37 · FY2024 · AI

Collaborative Research: Probing the role of chemical modifications on structure, folding, and dynamics of tRNA isodecoders

$460,000
Harish Vashisth · University Of New Hampshire · · FY2025 · MPS

Novel Role for Host Immunostimulatory RNA in Antiviral Immune Defense

$459,982
Michaela Ulrike Gack · Cleveland Clinic Lerner Com-Cwru · R01 · FY2024 · AI

Novel Role for Host Immunostimulatory RNA in Antiviral Immune Defense

$459,982
Michaela Ulrike Gack · Cleveland Clinic Lerner Com-Cwru · R01 · FY2025 · AI

Novel Role for Host Immunostimulatory RNA in Antiviral Immune Defense

$459,982
Michaela Ulrike Gack · Cleveland Clinic Lerner Com-Cwru · R01 · FY2023 · AI

Targeting tumor architecture as a novel therapeutic strategy for pancreatic cancer

$459,941
Matteo Ligorio · Ut Southwestern Medical Center · R37 · FY2023 · CA

New Mouse Models to Investigate Neurological Defects Caused by Exocyst Mutations

$459,872
Ian G Macara · Vanderbilt University · R21 · FY2020 · NS

Characterizing noncoding GWAS variants in acute lymphoblastic leukemia treatment outcome

$459,852
Daniel Savic · St. Jude Children'S Research Hospital · R01 · FY2019 · CA

Targeting tumor architecture as a novel therapeutic strategy for pancreatic cancer

$459,799
Matteo Ligorio · Ut Southwestern Medical Center · R37 · FY2022 · CA

Self-Powered Sample Concentrating and CRISPR-based Biosensing for Moile HIV-1 RNA Detection

$459,781
Changchun Liu · University Of Connecticut Sch Of Med/Dnt · R61 · FY2022 · AI

Profiling and Mapping Core

$459,510
David Branch Moody · Brigham And Women'S Hospital · U19 · FY2022 · AI

A quantitative framework for understanding endosomal trafficking networks in Alzheimer's disease

$459,425
Jeffrey Wade Harper · Harvard Medical School · R01 · FY2020 · NS

A quantitative framework for understanding endosomal trafficking networks in Alzheimer's disease

$459,425
Jeffrey Wade Harper · Harvard Medical School · R01 · FY2022 · NS

A quantitative framework for understanding endosomal trafficking networks in Alzheimer's disease

$459,425
Jeffrey Wade Harper · Harvard Medical School · R01 · FY2021 · NS

A quantitative framework for understanding endosomal trafficking networks in Alzheimer's disease

$459,425
Jeffrey Wade Harper · Harvard Medical School · R01 · FY2019 · NS

Generation of DNA memory by bacterial CRISPR-Cas9 systems

$459,422
Yan Zhang · University Of Michigan At Ann Arbor · R35 · FY2025 · GM