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64,565 grants matching drug discovery

A New Class of Broad-Spectrum Antibacterial Agents to Treat Multi-Drug Resistant Pathogens

$1,000,000
Paul Sebahar · Curza Inc · R44 · FY2024 · AI

NIRT: Hierarchical Bionanomanufacturing

$1,000,000
Robert L Clark · Duke University · · FY2006 · ENG

Selective Decorporation Agents for NIAID

$1,000,000
Benjamin P Warner · Icagen, Inc. · R44 · FY2012 · AI

Assigning mode of action to phenotypically discovered anticancer leads.

$1,000,000
Sergei S Makarov · Attagene, Inc. · R44 · FY2024 · CA

Program 1: Therapeutic Development Program (TDP)

$1,000,000
William R. Montfort · University Of Arizona · P30 · FY2021 · CA

Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci

$1,000,000
Terry Roemer · Prokaryotics, Inc. · R44 · FY2020 · AI

Novel Combination Product with Activity Against MRSA, MDR-Enterics and Pseudomonas

$1,000,000
Christopher John Burns · Venatorx Pharmaceuticals, Inc. · R44 · FY2019 · AI

Investigational New Drug (IND)-enabling and Early-Stage Development of Selective, Reversible, Orally Bioavailable ALDH2 inhibitor ANS-00858 to Treat Alcohol Use Disorder.

$1,000,000
Brent Keith Blackburn · Amygdala Neurosciences, Inc. · U43 · FY2023 · AA

Molecular Biomedical Imaging Laboratory

$1,000,000
David Bluemke · National Institute Of Biomedical Imaging And Bioengineering · ZIA · FY2010 · EB

Random Shear Shuttle BAC Libraries for Antimicrobial Discovery from Soil Metageno

$1,000,000
David Alan Mead · Lucigen Corporation · R44 · FY2013 · AI

R-5280, A Novel Modified Superior Resistant Starch Therapy for Type 1 Diabetes

$1,000,000
Christian Furlan Freguia · Rise Therapeutics, Llc · R44 · FY2023 · DK

A parallelized computational microscope platform for high-throughput live imaging of patient-derived organoids

$1,000,000
Mark Harfouche · Ramona Optics, Inc. · R44 · FY2025 · CA

Development of the NephroPlate: A high-throughput kidney-on-a-chip platform for identifying chronic kidney disease therapies

$1,000,000
Kristin M Bircsak · Mimetas Us, Inc. · R44 · FY2022 · DK

D-ISN: TRACK 1: A Holistic Approach to Discovery, Modeling, and Interdiction of Drug and Human Trafficking Networks in the U.S. Southwest

$1,000,000
Dominique E Roe-Sepowitz · Arizona State University · · FY2021 · ENG

Collaborative Research: EPiQC: Enabling Practical-Scale Quantum Computation

$1,000,000
Andrew A Houck · Princeton University · · FY2018 · CSE

FET Medium: Next-generation DNA-based Computing and Memory Materials

$1,000,000
Mark Bathe · Massachusetts Institute Of Technology · · FY2024 · CSE

Program 1: Therapeutic Development Program (TDP)

$1,000,000
William R. Montfort · University Of Arizona · P30 · FY2020 · CA

Rapid discovery of thousands of intact biosynthetic gene pathways for bioactive natural product compounds from un-sequenced filamentous fungi using a novel FAC-NGS tool

$1,000,000
Chengcang Charles Wu · Intact Genomics, Inc. · R44 · FY2020 · AI

Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci

$1,000,000
Terry Roemer · Prokaryotics, Inc. · R44 · FY2019 · AI

Novel Combination Product with Activity Against MRSA, MDR-Enterics and Pseudomonas

$1,000,000
Christopher John Burns · Venatorx Pharmaceuticals, Inc. · R44 · FY2020 · AI

Assigning mode of action to phenotypically discovered anticancer leads.

$1,000,000
Sergei S Makarov · Attagene, Inc. · R44 · FY2023 · CA

Rapid structure-based software to enhance antibody affinity and developability for high-throughput screening: Aiming toward total in silico design of antibodies

$1,000,000
Steven Joseph Darnell · Dnastar, Inc. · R44 · FY2023 · AI

Enabling Toxoplasma gondii Kinome Directed Drug Discovery

$1,000,000
Reena Zutshi · Luceome Biotechnologies, Llc · R44 · FY2024 · AI

Augmenting the CMDKP with advanced features for understanding biological mechanisms

$999,999
Jason Flannick · Broad Institute, Inc. · UM1 · FY2025 · DK

KL4 Surfactant to Mitigate Radiation-Induced Lung Injury

$999,999
Robert Segal · Discovery Laboratories, Inc. · R44 · FY2014 · AI