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64,565 grants matching drug discovery

Simultaneous pharmacological profiling of oncogenic gene fusion proteins in cancer

$1,000,000
Alexander Federation · Talus Bioscience, Inc. · R44 · FY2024 · CA

Rapid discovery of thousands of intact biosynthetic gene pathways for bioactive natural product compounds from un-sequenced filamentous fungi using a novel FAC-NGS tool

$1,000,000
Chengcang Charles Wu · Intact Genomics, Inc. · R44 · FY2022 · AI

Narrow-spectrum Agents Acting against Helicobacter pylori

$1,000,000
Kenneth Coleman · Arietis · R44 · FY2013 · AI

UCSC-Buck Inst. Genome Data Analysis Center for TCGA Research Network (GDAC)

$1,000,000
David H Haussler · University Of California Santa Cruz · U24 · FY2009 · CA

Selective Decorporation Agents for NIAID

$1,000,000
Benjamin P Warner · Icagen, Inc. · R44 · FY2013 · AI

SQSTM1/p62-targeted Small Molecules for Multiple Myeloma Disease

$1,000,000
James Lee · Id4pharma, Llc · R44 · FY2019 · CA

Acquisition of High Performance Data and Computing Infrastructure to Advance Biomedical Research

$1,000,000
Thomas Furlani · State University Of New York At Buffalo · S10 · FY2019 · OD

Development of GPER Agonists as Cancer Therapeutics

$1,000,000
Tina Garyantes · Linnaeus Therapeutics, Llc · R44 · FY2020 · CA

Fully-Automated Lesion Characterization in Ultrawide-Field Retinal Images

$1,000,000
Sandeep Bhat · Eyenuk, Inc. · R44 · FY2020 · EY

Development of Small Antimicrobial Peptide Mimics as Drug-Resistant and Susceptib

$1,000,000
Richard W Scott · Polymedix, Inc, · R44 · FY2012 · AI

Third line treatment of drug resistant FLT3-positive acute myeloid leukemia with a novel FLT3 kinase inhibitor

$1,000,000
Frederick Wayne Holtsberg · Kinarx, Llc · R44 · FY2020 · CA

Development of Broad Spectrum Host Oriented Therapeutic Antibodies against Influe

$1,000,000
Wu-Bo Li · Functional Genetics, Inc. · R44 · FY2011 · AI

NQVL:QSTD:Pilot: Distributed-Entanglement Quantum Sensing of Chemical Properties (DQS-CP)

$1,000,000
Ezekiel Johnston-Halperin · Ohio State University, The · · FY2024 · MPS

Novel Spectinamide Antibiotics for the Treatment of MDR/XDR Tuberculosis

$1,000,000
Michelle M. Butler · Microbiotix, Inc · R44 · FY2020 · AI

Collaborative Research: EPiQC: Enabling Practical-Scale Quantum Computation

$1,000,000
Andrew A Houck · Princeton University · · FY2018 · CSE

Novel Combination Product with Activity Against MRSA, MDR-Enterics and Pseudomonas

$1,000,000
Christopher John Burns · Venatorx Pharmaceuticals, Inc. · R44 · FY2019 · AI

Simultaneous pharmacological profiling of oncogenic gene fusion proteins in cancer

$1,000,000
Alexander Federation · Talus Bioscience, Inc. · R44 · FY2023 · CA

Assigning mode of action to phenotypically discovered anticancer leads.

$1,000,000
Sergei S Makarov · Attagene, Inc. · R44 · FY2024 · CA

Protease-resistant D-peptide Inhibitors of Ebola Virus Entry

$1,000,000
Brett D Welch · Navigen, Inc. · R44 · FY2016 · AI

Scaling function-first antibody discovery leveraging memory B cells

$1,000,000
Joseph De Rutte · Partillion Bioscience Corporation · R44 · FY2025 · AI

Development of the NephroPlate: A high-throughput kidney-on-a-chip platform for identifying chronic kidney disease therapies

$1,000,000
Kristin M Bircsak · Mimetas Us, Inc. · R44 · FY2022 · DK

Development of GPER Agonists as Cancer Therapeutics

$1,000,000
Tina Garyantes · Linnaeus Therapeutics, Llc · R44 · FY2019 · CA

Derivation of human pluripotent stem cells using small molecules

$1,000,000
Yanhong Shi · Beckman Research Institute/City Of Hope · RC1 · FY2010 · NS

The Southwest National Primate Research Center

$1,000,000
Kenneth Parkhurst Trevett · Texas Biomedical Research Institute · P51 · FY2010 · RR

Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci

$1,000,000
Terry Roemer · Prokaryotics, Inc. · R44 · FY2020 · AI