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64,565 grants matching drug discovery

Novel Spectinamide Antibiotics for the Treatment of MDR/XDR Tuberculosis

$1,000,000
Michelle M. Butler · Microbiotix, Inc · R44 · FY2020 · AI

Collaborative Research: EPiQC: Enabling Practical-Scale Quantum Computation

$1,000,000
Kenneth R Brown · Duke University · · FY2018 · CSE

Therapeutic D-peptide Inhibitor of HIV Entry

$1,000,000
Alan L Mueller · Navigen, Inc. · R44 · FY2014 · AI

Program 1: Therapeutic Development Program (TDP)

$1,000,000
William R. Montfort · University Of Arizona · P30 · FY2020 · CA

Therapeutic Antibodies for CMV

$1,000,000
William Robert Usinger · Trellis Bioscience, Inc. · R44 · FY2013 · AI

Narrow-spectrum Agents Acting against Helicobacter pylori

$1,000,000
Kenneth Coleman · Arietis · R44 · FY2015 · AI

Therapeutic D-peptide Inhibitor of HIV Entry

$1,000,000
Alan L Mueller · Navigen, Inc. · R44 · FY2015 · AI

High-Throughput Identification of BoNT Inhibitors

$1,000,000
Scripps Research Institute · R01 · FY2005 · AI

Novel Targeted Nanomedicine Delivering MicroRNA-30-5p ReplacementTherapy for Multi-drug Resistant Cancer Treatment

$1,000,000
Anthony D Saleh · Mirecule, Inc. · U44 · FY2021 · CA

NIRT: Hierarchical Bionanomanufacturing

$1,000,000
Robert L Clark · Duke University · · FY2006 · ENG

NQVL:QSTD:Pilot: Quantum Computing Applications of Photonics (QCAP)

$1,000,000
Marek Osinski · University Of New Mexico · · FY2024 · MPS

Rapid discovery of thousands of intact biosynthetic gene pathways for bioactive natural product compounds from un-sequenced filamentous fungi using a novel FAC-NGS tool

$1,000,000
Chengcang Charles Wu · Intact Genomics, Inc. · R44 · FY2022 · AI

Identifying chemical probes against all essential genes

$1,000,000
Stanford University · R01 · FY2004 · HG

Optimization of novel pyranopyridine efflux pump inhibitors

$1,000,000
Timothy J Opperman · Microbiotix, Inc · R44 · FY2021 · AI

Multispray Technology for Studying Biomolecular Interactions

$1,000,000
Daojing Wang · Newomics, Inc · R44 · FY2025 · GM

SBIR Phase II: Proteome Epitope Tags-Based Antibody Arrays for High-Throughput, Proteome-Wide Kinase Pathway Profiling

$1,000,000
Neal F Gordon · Epitome Biosystems, Inc. · · FY2005 · TIP

Rapid structure-based software to enhance antibody affinity and developability for high-throughput screening: Aiming toward total in silico design of antibodies

$1,000,000
Steven Joseph Darnell · Dnastar, Inc. · R44 · FY2023 · AI

UCSC-Buck Inst. Genome Data Analysis Center for TCGA Research Network (GDAC)

$1,000,000
David H Haussler · University Of California Santa Cruz · U24 · FY2009 · CA

Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci

$1,000,000
Terry Roemer · Prokaryotics, Inc. · R44 · FY2020 · AI

NQVL:QSTD:Pilot: Quantum Blueprint: Optimizing Analog Pathways in Diverse Scientific Realms (Q-BLUE)

$1,000,000
Mark S Gordon · Iowa State University · · FY2024 · MPS

EXTRA RES FACIL: FUNGI, GENOMICS, PROTEOMICS, DRUG DISCOVERY, BIOINFORMATICS

$1,000,000
Albert Einstein Col Of Med Yeshiva Univ · C06 · FY2005 · RR

Derivation of human pluripotent stem cells using small molecules

$1,000,000
Yanhong Shi · Beckman Research Institute/City Of Hope · RC1 · FY2010 · NS

Human NeuromuscularJunction Platform to Evaluate Botulinum Toxin Potency

$1,000,000
James F Kronauge · Hesperos, Llc · U44 · FY2024 · TR

DEVELOPMENT OF A WNT PATHWAY INHIBITOR FOR METASTATIC COLORECTAL CANCER

$1,000,000
Darren Orton · Stemsynergy Therapeutics, Inc. · R44 · FY2017 · CA

Assigning mode of action to phenotypically discovered anticancer leads.

$1,000,000
Sergei S Makarov · Attagene, Inc. · R44 · FY2023 · CA