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10,766 grants matching checkpoint inhibitor

Impact of CREB-driven mechanism in shaping the tumor-immune landscape

$324,760
Nagaraj S. Nagathihalli · University Of Miami School Of Medicine · R01 · FY2023 · CA

Development of antisense oligonucleotides that enhance sIL7R as novel cancer immunotherapy

$324,675
Gaddiel Galarza-Munoz · Autoimmunity Biologic Solutions, Inc. · R43 · FY2021 · CA

Targeting EphB4-ephrinB2 to decrease immunosuppression in HNSCC

$324,670
Sana D Karam · University Of Colorado Denver · P50 · FY2023 · CA

Molecular Targeted Radionuclide Therapy with Tumor-Specific Vaccine to Stimulate and Expand T-cell Activation

$324,587
Douglas G McNeel · University Of Wisconsin-Madison · P01 · FY2020 · CA

Project 2: Measuring and modeling the tumor and immune microenvironment before and during therapy and at the time of drug resistance

$324,561
Arlene H Sharpe · Harvard Medical School · U54 · FY2019 · CA

Investigating multifactorial beta-catenin activation in hepatocellular cancers

$324,555
Xin Chen · University Of Hawaii At Manoa · R01 · FY2022 · CA

E2A/HEB TRANSCRIPTION FACTORS IN T CELL DEVELOPMENT

$324,324
Yuan Zhuang · Duke University · R01 · FY2010 · GM

Stinging the Glioma Immune Landscape

$324,017
Amy Beth Heimberger · Northwestern University At Chicago · R01 · FY2023 · NS

Project 2: Re-directing the Sensitivity of Metastatic Castration-Resistant Prostate Cancer to Immunotherapy

$324,002
Jennifer D Wu · Northwestern University At Chicago · P50 · FY2021 · CA

Function and mechanism of REDD1 signaling to TSC1/2 and mTORC1

$323,950
Leif W Ellisen · Massachusetts General Hospital · R01 · FY2010 · CA

Metabolic reprogramming of the tumor microenvironment and therapy resistance

$323,925
Ernst Lengyel · University Of Chicago · R35 · FY2021 · CA

ATM as target for malignant glioma radiosensitization.

$323,762
Kristoffer Valerie · Virginia Commonwealth University · R01 · FY2010 · NS

Hematopoietic stem cells overcome treatment resistance to PD-1 blockade against brain tumors

$323,587
Catherine T Flores · University Of Florida · R01 · FY2024 · NS

The Role of AKT in Prostate Cancer

$323,496
William R Sellers · Beth Israel Deaconess Medical Center · P01 · FY2011 · CA

Mechanism of ultraviolet radiation induced immune tolerance

$323,433
Hui Xu · University Of Alabama At Birmingham · R01 · FY2022 · AR

A Registry-Based Study of Patterns of Use of Targeted Therapies for Metastatic Cancers in Diverse Populations

$323,297
Christine Veenstra · University Of Michigan At Ann Arbor · R37 · FY2025 · CA

Project 3 - Targeting CDK4/6 to modulate immunogenicity in gliomas (Wen/Zhao)

$323,272
Jean Zhao · Brigham And Women'S Hospital · P50 · FY2019 · CA

Targeting EphB4-ephrinB2 to decrease immunosuppression in HNSCC

$323,204
Sana D Karam · University Of Colorado Denver · P50 · FY2024 · CA

Effects of ATR-CHK1 inhibition on genome stability and cancer progression

$323,192
Eric J Brown · University Of Pennsylvania · R01 · FY2018 · CA

ATM as target for malignant glioma radiosensitization.

$323,135
Kristoffer Valerie · Virginia Commonwealth University · R01 · FY2009 · NS

Project 1

$323,023
Mark M. Awad · Dana-Farber Cancer Inst · P50 · FY2023 · CA

The MRAD9 Radioresistance Gene

$323,004
Howard B Lieberman · Columbia University Health Sciences · R01 · FY2013 · GM

Impact of Irreversible T Cell Dysfunction on Transplant Outcomes

$323,000
Wenhao Chen · Methodist Hospital Research Institute · R56 · FY2024 · AI

Core 1: Mouse Model and Tissue Biobank Core

$322,871
Roger S Lo · Institute For Systems Biology · U54 · FY2022 · CA

Study of Anti-Survival signals in NF1

$322,663
Changyan Chen · Northeastern University · R01 · FY2016 · CA