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17,828 grants matching crispr

Targeting Systems Vulnerabilities in the EGFR/HER3/HER2 Oncogenic Signaling Circuitry: New Precision Therapies for Oral Cancer

$483,360
J. Silvio Gutkind · University Of California, San Diego · R01 · FY2025 · DE

UC Irvine AD Translational Center for Disease Model Resources-Aging Supplement

$483,142
Frank M Laferla · University Of California-Irvine · U54 · FY2019 · AG

Decoding the Interferome by Mapping Genetic Interactions in Human Tissue

$483,134
Ryan Gilbert Gaudet · Columbia University Health Sciences · DP2 · FY2023 · AI

Metabolic activation of nitroarenes and Nrf2-Keap1

$483,121
Trevor M. Penning · University Of Pennsylvania · R01 · FY2019 · ES

Mechanisms of Epidermal Homeostasis and Early Neoplasia

$483,048
Paul A Khavari · Stanford University · R01 · FY2019 · AR

Targeting CEBPA To Restore Epithelial-Mesenchymal Homeostasis In Lung Fibrosis

$483,042
Qi Tan · Mayo Clinic Rochester · R01 · FY2021 · HL

Project 2 Human Tumor Analysis

$482,856
Sylvia Katina Plevritis · Stanford University · U54 · FY2024 · CA

Spatiotemporal Control of T cell Synapse Stabilization and Signaling

$482,847
Matthew F Krummel · University Of California, San Francisco · R01 · FY2020 · AI

Project 3: Identifying transcriptional driver genes and targeting transcription in TSC

$482,742
David J. Kwiatkowski · Brigham And Women'S Hospital · P01 · FY2022 · CA

Functional dissection of fibronectin type 3 domains of SORL1 in Alzheimers disease associated microglia

$482,708
Falak Sher · Columbia University Health Sciences · R01 · FY2023 · AG

Role reversal of MAVS in bacterial sepsis

$482,381
Markus Bosmann · Boston University Medical Campus · R01 · FY2021 · HL

Role reversal of MAVS in bacterial sepsis

$482,381
Markus Bosmann · Boston University Medical Campus · R01 · FY2022 · HL

Role reversal of MAVS in bacterial sepsis

$482,381
Markus Bosmann · Boston University Medical Campus · R01 · FY2019 · HL

Role reversal of MAVS in bacterial sepsis

$482,381
Markus Bosmann · Boston University Medical Campus · R01 · FY2020 · HL

Role reversal of MAVS in bacterial sepsis

$482,381
Markus Bosmann · Boston University Medical Campus · R01 · FY2018 · HL

A quantitative framework for understanding endosomal trafficking networks in Alzheimer's disease

$482,307
Jeffrey Wade Harper · Harvard Medical School · R01 · FY2018 · NS

Iterative Polyketide Synthase Function, Structure and Pathways

$482,226
Craig A Townsend · Johns Hopkins University · R01 · FY2019 · ES

Bacteriophage diversity, dynamics, function, and exploitation

$482,168
Graham F. Hatfull · University Of Pittsburgh At Pittsburgh · R35 · FY2024 · GM

Bacteriophage diversity, dynamics, function, and exploitation

$482,168
Graham F. Hatfull · University Of Pittsburgh At Pittsburgh · R35 · FY2025 · GM

Deconstructing and targeting aneuploidy in human cancer - Resubmission - 1

$482,077
Teresa Davoli · New York University School Of Medicine · R37 · FY2023 · CA

Elucidating the Functional and Mechanistic Roles of LINE-1 Retrotransposons in Myeloid Leukemia

$482,075
Jian Xu · St. Jude Children'S Research Hospital · R01 · FY2025 · CA

Multisite phosphorylated S6K1 directs a regulatory module determining adipocyte lipid metabolism

$482,054
Paul L Fox · Cleveland Clinic Lerner Com-Cwru · R01 · FY2020 · DK

GOALI: Rewiring Escherichia coli for the efficient synthesis of chondroitin polysaccharides

$482,000
Mattheos Koffas · Rensselaer Polytechnic Institute · · FY2016 · ENG

MorPhiC: Constructing a Catalog of Cellular Programs to Identify and Annotate Human Disease Genes

$481,992
Jesse M Engreitz · Stanford University · U01 · FY2025 · HG

Epigenetics of inner ear neurosensory cell development

$481,987
Donna M Martin · University Of Michigan At Ann Arbor · R01 · FY2023 · DC