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17,054 grants matching genome editing

Enhancing cone survival in retinitis pigmentosa through cell-specific therapeutic CRISPR editing of a roxadustat target

$529,817
Stephen H Tsang · Columbia University Health Sciences · R01 · FY2023 · EY

Myosin Gene Diversity and Function

$529,803
Leslie Anne Leinwand · University Of Colorado · R01 · FY2021 · GM

Collaborative Research: Discrete and Topological Models for Template-Guided Genome Rearrangements

$529,683
Natasa Jonoska · University Of South Florida · · FY2018 · MPS

Optimizing Surgical Transplant of CFTR Gene-Corrected Human Basal Stem Cells to the Upper Airway

$529,683
Jayakar V Nayak · Stanford University · R01 · FY2021 · HL

Development of Novel Informative Preclinical Animal Models - CAPR Infrastructure

$529,416
Shyam Sharan · Division Of Basic Sciences - Nci · ZIG · FY2018 · CA

Molecular Mechanisms of Insulin Resistance Associated Loci

$529,300
Thomas None Quertermous · Stanford University · R01 · FY2016 · DK

Establishing and reversing the functional consequences of Titin truncation mutations

$529,054
John Travis Hinson · University Of Connecticut Sch Of Med/Dnt · R01 · FY2025 · HL

Establishing and reversing the functional consequences of Titin truncation mutations

$529,054
John Travis Hinson · University Of Connecticut Sch Of Med/Dnt · R01 · FY2023 · HL

Impact of Genetic Variation on Folate Metabolism: Etiology of Neural Tube Defect

$529,029
Jasper D Rine · University Of California Berkeley · R01 · FY2014 · GM

Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapies

$528,922
Lisa Maves · Seattle Children'S Hospital · R01 · FY2025 · AR

Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapies

$528,922
Lisa Maves · Seattle Children'S Hospital · R01 · FY2024 · AR

Characterization of SynGAP Mutations in Human Cognitive Disorders

$528,913
Richard L Huganir · Johns Hopkins University · R01 · FY2020 · MH

Characterization of SynGAP Mutations in Human Cognitive Disorders

$528,913
Richard L Huganir · Johns Hopkins University · R01 · FY2021 · MH

Characterization of SynGAP Mutations in Human Cognitive Disorders

$528,913
Richard L Huganir · Johns Hopkins University · R01 · FY2019 · MH

Mechanisms driving lung cancer evolution during targeted kinase inhibitor treatment

$528,861
Aaron N Hata · Massachusetts General Hospital · R01 · FY2024 · CA

Characterization of SynGAP Mutations in Human Cognitive Disorders

$528,576
Richard L Huganir · Johns Hopkins University · R01 · FY2018 · MH

Regulation of Foamy Macrophage Differentiation and Survival in Atherosclerosis

$528,459
Jesse Warren Williams · University Of Minnesota · R01 · FY2025 · HL

Regulation and Function of SRF in Vascular Pathiobiology

$528,402
Joseph M Miano · Augusta University · R01 · FY2021 · HL

Regulation and Function of SRF in Vascular Pathiobiology

$528,402
Joseph M Miano · Augusta University · R01 · FY2022 · HL

Natural Killer Cell Tolerance to Self

$528,312
Wayne M. Yokoyama · Washington University · R01 · FY2017 · AI

Mechanisms driving lung cancer evolution during targeted kinase inhibitor treatment

$528,039
Aaron N Hata · Massachusetts General Hospital · R01 · FY2022 · CA

Novel Genome Editing for the Treatment of Glaucoma

$527,925
Val C Sheffield · University Of Iowa · R01 · FY2021 · EY

Actionable Ethics Oversight for Human-Animal Chimera Research

$527,906
Josephine Marguerite Johnston · Hastings Center, Inc. · R01 · FY2019 · HG

Desmoplastic small round cell tumor: harnessing new insights and new models

$527,904
Marc Ladanyi · Sloan-Kettering Inst Can Research · U01 · FY2024 · CA

Mechanistic analysis and allellic genome editing of iPSC-derived dominant LCA model

$527,898
Deepak Ashok Lamba · University Of California, San Francisco · R01 · FY2023 · EY