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10,766 grants matching checkpoint inhibitor

Dissecting the source and mechanisms of IL-17-mediated modulation of pancreatic tumorigenesis

$370,575
Florencia McAllister · University Of Tx Md Anderson Can Ctr · R37 · FY2022 · CA

Harnessing Aurora kinase inhibition‐induced cell death to enhance immunotherapy in HPV‐driven cancers

$370,575
Faye Johnson · University Of Tx Md Anderson Can Ctr · R01 · FY2021 · CA

Dissecting and targeting mechanisms of genomic instability-triggered immune evasion in RBM10-deficient non-small cell lung cancer

$370,575
Ferdinandos Skoulidis · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · CA

Understanding and harnessing immune-modulatory effects of covalent KRASG12C inhibitors in KRASG12C-mutant non-small cell lung cancer

$370,575
Ferdinandos Skoulidis · University Of Tx Md Anderson Can Ctr · R01 · FY2021 · CA

Harnessing Aurora kinase inhibition‐induced cell death to enhance immunotherapy in HPV‐driven cancers

$370,575
Faye Johnson · University Of Tx Md Anderson Can Ctr · R01 · FY2020 · CA

Use of focused ultrasound to increase melanoma immunogenicity and inhibit tumor-induced T cell tolerance

$370,552
Fernando Macian · Albert Einstein College Of Medicine · R01 · FY2019 · CA

Project 2: Targeting DNA replication in BRCA-associated breast cancer

$370,550
Bing Xia · Rbhs -Cancer Institute Of New Jersey · P01 · FY2021 · CA

Mechanistic investigations of microbiome-driven aryl hydrocarbon receptor activity and macrophage function in pancreatic cancer.

$370,513
Tracy L McGaha · University Health Network · R01 · FY2025 · CA

Skeletal survivorship and immune therapy: The effects of nivolumab on bone metabolism in renal cell carcinoma

$370,511
Kendall Moseley · Johns Hopkins University · R21 · FY2019 · AR

Combinatorial Targeting of Epigenomic and Microenvironmental Pathways to Suppress MAPK Inhibitor Resistance in Melanoma

$370,500
Roger S Lo · University Of California Los Angeles · R01 · FY2020 · CA

Develop a Therapeutic Nano-vaccine against Head and Neck Cancer

$370,500
Yu Leo Lei · University Of Michigan At Ann Arbor · R01 · FY2021 · DE

FOXD3 up-regulation and ERBB3 signaling as an adaptive response to BRAF inhibitors in melanoma

$370,500
Andrew E Aplin · Thomas Jefferson University · R01 · FY2020 · CA

Combinatorial Targeting of Epigenomic and Microenvironmental Pathways to Suppress MAPK Inhibitor Resistance in Melanoma

$370,500
Roger S Lo · University Of California Los Angeles · R01 · FY2019 · CA

FOXD3 up-regulation and ERBB3 signaling as an adaptive response to BRAF inhibitors in melanoma

$370,500
Andrew E Aplin · Thomas Jefferson University · R01 · FY2018 · CA

Targeted therapies in cutaneous melanoma

$370,500
Andrew E Aplin · Thomas Jefferson University · R01 · FY2020 · CA

Develop a Therapeutic Nano-vaccine against Head and Neck Cancer

$370,500
Yu Leo Lei · University Of Michigan At Ann Arbor · R01 · FY2019 · DE

Develop a Therapeutic Nano-vaccine against Head and Neck Cancer

$370,500
Yu Leo Lei · University Of Michigan At Ann Arbor · R01 · FY2020 · DE

Targeted therapies in cutaneous melanoma

$370,500
Andrew E Aplin · Thomas Jefferson University · R01 · FY2021 · CA

Combinatorial Targeting of Epigenomic and Microenvironmental Pathways to Suppress MAPK Inhibitor Resistance in Melanoma

$370,500
Roger S Lo · University Of California Los Angeles · R01 · FY2021 · CA

FOXD3 up-regulation and ERBB3 signaling as an adaptive response to BRAF inhibitors in melanoma

$370,500
Andrew E Aplin · Thomas Jefferson University · R01 · FY2021 · CA

Regulation of GLI1, a synthetic lethal target of SMARCA4-deficiency, in lung adenocarcinoma

$370,338
James Kim · Ut Southwestern Medical Center · R01 · FY2024 · CA

Robust-to-fragile transitions of a phase-separated mitotic organelle in triple-negative breast cancer

$370,150
P. Todd Stukenberg · University Of Virginia · U54 · FY2022 · CA

Re-activating Memory T Cells in the Microenvironment of Human Tumors

$370,088
Richard B Bankert · State University Of New York At Buffalo · R01 · FY2008 · CA

Translational Events in Platelets

$370,013
Andrew Scott Weyrich · University Of Utah · R01 · FY2012 · HL

Project 1: Targeting Metabolic Dependencies in PDAC

$369,941
Ronald Anthony Depinho · University Of Tx Md Anderson Can Ctr · P01 · FY2018 · CA