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38,696 grants matching “als”
Optimizing oscillatory epidural electrical stimulation to selectively increase task-related population dynamics in motor areas
$709,020Karunesh Ganguly · University Of California, San Francisco · R01 · FY2022 · NS
HIV/Drug Abuse Prevention for homeless Youth & Families
$708,980Mary McKernan McKay · Icahn School Of Medicine At Mount Sinai · R01 · FY2007 · DA
THE GOAL OF THE PROPOSED APPLICATIONS RESEARCH IS TO ADVANCE KNOWLEDGE OF DATA INTEGRATION WITH NASA EARTH OBSERVATIONS CLIMATE DATA FIELD-COLLECTED BIODIVERSITY DATA AND ECOLOGICAL MODELS TO HELP NATIONS REPORT IN AN ACCURATE AND TIMELY WAY ON SUSTAINABLE DEVELOPMENT GOAL 15 ( LIFE ON LAND. ) SPECIFICALLY WE SEEK TO DEVELOP TEST AND DEMONSTRATE TO GOVERNMENTS A NEAR-REAL TIME INTEGRATED MAPPING AND REPORTING SYSTEM THAT PRODUCES REGIONAL RESULTS ABOUT SITES IMPORTANT FOR BIODIVERSITY AS DESCRIBED IN SDG INDICATOR 15.1.2. BY NEAR-REAL-TIME WE MEAN REPEATING ANALYSES AS OFTEN THE UNDERLYING SATELLITE OR FIELD DATA CHANGE. OUR PROPOSAL FOCUSES ON TIGERS (PANTHERA TIGRIS) AS AN EXAMPLE IMPLEMENTING WELL-ESTABLISHED MODELS ON A CLOUD-BASED GEOSPATIAL COMPUTING PLATFORM (E.G. GOOGLE EARTH ENGINE) AND SERVING DATA BY WEB PORTAL. WE PROPOSE TO COMPUTE INTEGRATIVE MODELS OF TIGER CONSERVATION LANDSCAPES (TCLS; DINERSTEIN ET AL. 2007 SANDERSON ET AL. 2006) AND SOURCE SITES (SSS; WALSTON ET AL. 2010) IN TIME SERIES AND ANALYZE THESE CRITICAL SITES IN RELATION TO PROTECTED AREAS AND ECOSYSTEMS ON A COUNTRY-BY-COUNTRY BASIS LOOKING BACK TO THE YEAR 2000 AND FORWARD THROUGH AT LEAST 2030. WE WILL ALSO COMPUTE NEW 1 KM2 RESOLUTION HUMAN FOOTPRINT MAPS (SENSU SANDERSON ET AL. 2002; SEE VENTER ET AL. 2016) ON AN ANNUAL BASIS GLOBALLY. WHAT TIGERS NEED IS ANALOGOUS TO WHAT MANY WILDLIFE SPECIES NEED: INTACT PATCHES OF ECOSYSTEMS WITH SUITABLE STRUCTURAL CHARACTERISTICS OF ECOSYSTEMS SOME OF WHICH ARE REMOTELY SENSIBLE; FREEDOM FROM TOO MUCH HUMAN INFLUENCE AS MEASURED BY THE HUMAN FOOTPRINT; AND INTERCONNECTED BLOCKS OF UNDIMINISHED HABITAT LARGE ENOUGH TO SUPPORT A POPULATION. CLIMATE CHANGE IMPACTS ALL THESE FACTORS AND NEW SATELLITE OBSERVATIONS SUCH AS THE FIRE INFORMATION FOR RESOURCE MANAGEMENT SYSTEM (FIRMS) AND ANNUALIZED LAND COVER PRODUCTS FROM MODIS ALLOW US TO DETECT SIGNIFICANT CHANGES IN LANDSCAPE CHARACTERISTICS. STRUCTURED IF ASYNCHRONOUS FIELD DATA COLLECTIONS ACROSS 10 COUNTRIES IN ASIA WILL ENABLE US TO CALIBRATE MODELS GENERATE UP-TO-DATE FINDINGS AND VALIDATE THE RESULTS. COUNTRIES NEED TIME-SERIES NOT SNAPSHOTS TO SHOW CHANGE AND RESPOND EFFECTIVELY TO THEIR INTERNATIONAL COMMITMENTS AND NATIONAL GOALS. HERE THEY WILL RECEIVE THEM WHENEVER OBSERVATIONS CHANGE THROUGH THEIR INTERNET BROWSER AS BOTH TOP-LEVEL INDICATORS (E.G. AREA OF TCLS AND SSS PROTECTED) AND AS DOWNLOADABLE GEOSPATIAL LAYERS WITH 1 KM2 MINIMUM MAP UNITS. ALTHOUGH TIGERS ARE ONLY ONE OF THE MILLIONS OF SPECIES THAT LIVE IN SOUTHERN AND EASTERN ASIA THIS TYPE B APPLICATIONS PROPOSAL WILL PROVIDE A HIGH-PROFILE WORKING EXAMPLE OF SCIENTIFIC FUSION OF NASA SATELLITE DATA COLLECTIONS WITH THE EFFORTS OF GOVERNMENTS AND NON-GOVERNMENTAL ORGANIZATIONS TO OBSERVE DOCUMENT AND CONSERVE ENDANGERED SPECIES OF MANY KINDS AS THE CLIMATE CHANGES.
$708,930Wildlife Conservation Society · · FY2020 · National Aeronautics and Space Administration
Biochemical Mechanisms of Enzyme Action and Cellular Regulation
$708,889P. Boon Chock · National Heart, Lung, And Blood Institute · ZIA · FY2012 · HL
Integrated eHealth for HIV and Substance Use Disorders in Justice-involved Women
$708,877Jaimie Meyer · Yale University · R01 · FY2023 · DA
Targeting the gut-brain axis to facilitate weight loss in high fat diet consumers
$708,797Dana M Small · Yale University · R01 · FY2022 · DK
Clinical Diagnostic Sequencing of Structural Variation
$708,770Michael E Talkowski · Massachusetts General Hospital · R01 · FY2016 · HD
OSUCCC CUSP2CT
$708,750Electra D. Paskett · Ohio State University · U01 · FY2022 · CA
C9orf72 frontotemporal dementia (FTD) and amyotrophic lateral sclerosis(ALS): using patient cells and CRISPR to reveal therapeutic approaches
$708,750Bruce R Conklin · J. David Gladstone Institutes · R01 · FY2024 · AG
Native Navigators and the Cancer Continuum (NNACC)
$708,711Linda Burhansstipanov · Native American Cancer Research · R24 · FY2011 · MD
GENOMIC STUDIES OF THE HUMAN Y CHROMOSOME
$708,693Whitehead Institute For Biomedical Res · R01 · FY2001 · HG
Retroviral Replication and Interactions with Host Factors
$708,607Vinay K. Pathak · Division Of Basic Sciences - Nci · ZIA · FY2016 · CA
Improving PTSD Management in Primary Care
$708,253Lisa Seidel Meredith · Rand Corporation · R01 · FY2009 · MH
A microphysiologic multicellular organ-on-chip to inform clinical trials in FTD/ALS
$708,245Clive Niels Svendsen · Cedars-Sinai Medical Center · UH3 · FY2023 · TR
3/3 Genomics of Schizophrenia in the South African Xhosa
$708,041Dan Joseph Stein · University Of Cape Town · U01 · FY2021 · MH
Motor Activity Research Consortium for Health (mMarch)
$707,648Kathleen R Merikangas · National Institute Of Mental Health · ZIA · FY2018 · MH
Population-Based Epidemiologic Research
$707,648Kathleen R Merikangas · National Institute Of Mental Health · ZIA · FY2018 · MH
Translation dysregulation in neurodegeneration
$707,634Daniela C Zarnescu · Pennsylvania State Univ Hershey Med Ctr · R01 · FY2025 · NS
Cyclic EphA4 peptide antagonists for neuroprotection in ALS
$707,562Elena B Pasquale · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2014 · NS
Autoimmunity Center of Excellence (ACE) at Stanford
$707,559Charles Garrison Fathman · Stanford University · U19 · FY2009 · AI
Phase II Clinical Trial of Polyphenon E in Prostate Cancer
$707,275Nagi B Kumar · H. Lee Moffitt Cancer Ctr & Res Inst · R01 · FY2009 · CA
LONGITUDINAL NEUROIMAGING AND MOLECULAR BIOMARKERS OF CEREBROVASCULAR HEALTH IN ALS
$707,134Dignity Health · · FY2025 · Defense Health Agency
Understanding Immune Evasion by HIV-1 Repliclones
$707,074Elias K. Halvas · University Of Pittsburgh At Pittsburgh · R01 · FY2024 · AI
Expanding the reach of the Nutritious Eating with Soul (NEW Soul) program: A Type 2 hybrid effectiveness-implementation trial
$706,953Gabrielle Michelle Turner-McGrievy · University Of South Carolina At Columbia · R01 · FY2024 · HL
Maximizing Therapeutic Accumulation and Retention for Enhanced Cardiac Repair
$706,718Juliane Nguyen · Univ Of North Carolina Chapel Hill · R01 · FY2024 · HL