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10,766 grants matching checkpoint inhibitor

Targeting the immunosuppressive adenosine-axis to overcome T-cell γc cytokine signaling blockade and enhance antitumor immunity in hepatocellular carcinoma

$378,246
Yong Qin · University Of Texas El Paso · U54 · FY2025 · MD

The Role of Stromal Autophagy in Cutaneous Melanoma

$378,218
Hilary A Coller · University Of California Los Angeles · R01 · FY2018 · CA

A novel more effective genotoxic therapy for ovarian cancer

$378,217
Fiona Simpkins · University Of Pennsylvania · R37 · FY2024 · CA

Novel Nano-immunotherapy for Treatment of Non-small Cell Lung Cancer

$378,030
Worapol Ngamcherdtrakul · Pdx Pharmaceuticals, Inc. · R44 · FY2021 · CA

Project 3: Localized microneedle-directed combination immunotherapy for cSCC

$378,023
Louis D Falo · University Of Pittsburgh At Pittsburgh · P50 · FY2022 · CA

Mechanisms of radioresistance and strategies for radiosensitization in OCCC

$377,816
Guang Peng · University Of Tx Md Anderson Can Ctr · R01 · FY2016 · CA

Molecular Events Initiating B Cell Fate Determination

$377,750
Kay Lynn Medina · Mayo Clinic Rochester · R01 · FY2011 · HL

Molecular Events Initiating B Cell Fate Determination

$377,750
Kay Lynn Medina · Mayo Clinic Rochester · R01 · FY2010 · HL

Molecular Events Initiating B Cell Fate Determination

$377,750
Kay Lynn Medina · Mayo Clinic Rochester · R01 · FY2009 · HL

Molecular Events Initiating B Cell Fate Determination

$377,750
Kay Lynn Medina · Mayo Clinic Rochester · R01 · FY2012 · HL

Mitochondrial stress promotes immunosuppressive potential of myeloid subsets in tumors

$377,735
Paulo Cesar Rodriguez · H. Lee Moffitt Cancer Ctr & Res Inst · R01 · FY2023 · CA

Role of exosomal SPHK1 in ovarian cancer progression

$377,679
Sunila Pradeep · Medical College Of Wisconsin · R01 · FY2022 · CA

Replication Associated Genetic Rearrangements

$377,645
Brandeis University · R01 · FY2005 · GM

Development and Mechanistic Studies of an Engineered Human Enzyme to Abrogate Immune Suppression due to Elevated Methylthioadenosine (MTA) by MTAP null/low Tumors

$377,573
Everett Stone · University Of Texas At Austin · R01 · FY2020 · CA

Novobiocin-mediated polymerase theta inhibition in homologous recombination repair-deficient cancers

$377,516
Geoffrey I Shapiro · Dana-Farber Cancer Inst · R01 · FY2024 · CA

(PQ11) Targeting STING in the context of chemoradiation therapy to overcome poor preexisting immunity in mouse models of pancreatic cancer.

$377,438
Marka Crittenden · Providence Portland Medical Center · R01 · FY2020 · CA

(PQ11) Targeting STING in the context of chemoradiation therapy to overcome poor preexisting immunity in mouse models of pancreatic cancer.

$377,438
Marka Crittenden · Providence Portland Medical Center · R01 · FY2018 · CA

(PQ11) Targeting STING in the context of chemoradiation therapy to overcome poor preexisting immunity in mouse models of pancreatic cancer.

$377,438
Marka Crittenden · Providence Portland Medical Center · R01 · FY2017 · CA

Project 1: Promoting Graft-versus-Tumor Effects in the Bone Marrow

$377,415
Geoffrey Roger Hill · Fred Hutchinson Cancer Research Center · P01 · FY2020 · CA

In situ radioimmunotherapy to maximize the engagement of conventional type 1 dendritic cells against non-T cell-inflamed tumors

$377,327
Fumito Ito · University Of Southern California · R01 · FY2024 · CA

Checkpoints of TNF Gene Regulation

$377,234
Anne Goldfeld · Immune Disease Institute, Inc. · R01 · FY2009 · GM

Control of Cell Fate and Proliferation in the Developing Eye

$377,219
Utpal Banerjee · University Of California Los Angeles · R01 · FY2009 · EY

Control of Cell Fate and Proliferation in the Developing Eye

$377,219
Utpal Banerjee · University Of California Los Angeles · R01 · FY2007 · EY

Nanoformulated small molecule immunotherapy for SHH medulloblastoma

$377,088
Marina Sokolsky-Papkov · Univ Of North Carolina Chapel Hill · R01 · FY2024 · NS

Immunological, serologic, and imaging biomarker predictors of flare in pediatric spondyloarthritis

$377,034
Pamela Fitch Weiss · Children'S Hosp Of Philadelphia · R01 · FY2024 · AR