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15,273 grants matching “antimicrobial resistance”
Drosophila melanogaster as a model host for Vibrio cholerae
$414,473Paula I Watnick · Boston Children'S Hospital · R01 · FY2008 · AI
Colorado Emerging Infections Program-ARRA-HAI
$414,402Ken A. Gershman · Colorado State Dept/Pub Hlth & Environmt · U01 · FY2009 · CI
ALTERNATIVE APPROACHES FOR E FAECALIS INFECTIONS
$414,389Barbara E Murray · University Of Texas Hlth Sci Ctr Houston · R37 · FY2009 · AI
Quinolone Resistance Mechanisms in Staphylococcus aureus
$414,250Massachusetts General Hospital · R01 · FY2003 · AI
Exploring Peptide Conjugates as Trojan Horse Systems for Drug Design and Discovery
$413,897Satish K Nair · University Of Illinois At Urbana-Champaign · R01 · FY2020 · AI
Enhancing the Capacity and Capability of Human Food and Environmental Testing Laboratory at the Texas Department of State Health Services: Overall
$413,800Susan Tanksley · Texas State Dept Of Health Services · U19 · FY2021 · FD
Regulation of motility and organelle assembly at the Pseudomonas aeruginosa pole
$413,750Barbara I Kazmierczak · Yale University · R01 · FY2010 · AI
Target-based Assays and Screening Strategies for Chemical Probe and Therapeutic Lead Discovery
$413,556James Inglese · National Center For Advancing Translational Sciences · ZIA · FY2019 · TR
Tinidazole for the Treatment of Bacterial Vaginosis
$413,450Jane R. Schwebke · University Of Alabama At Birmingham · R01 · FY2007 · AI
**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** PEANUTS AND TREE NUTS ARE HIGH-RISK FOODS CONCERNING SALMONELLA CONTAMINATION, DUE TO THE MAJOR OUTBREAKS ASSOCIATED WITH TREE NUTS AND COMMERCIALLY PRODUCED PEANUT BUTTER. IT IS WELL ESTABLISHED THAT SALMONELLA SP. EXHIBIT HIGHER HEAT RESISTANCE IN HIGH FAT, LOW WATER ACTIVITY ENVIRONMENTS. CLEANING COMMERCIAL OF PEANUT BUTTER AND OTHER NUT PASTE FACILITIES IS ESPECIALLY CHALLENGING, DUE TO THE HIGH-FAT CONTENT OF PEANUTS, THE IMMISCIBLE NATURE OF NUT BUTTER AND WATER, AND THE PRESENCE OF LIQUID IN THE PROCESSING ENVIRONMENT CAN PROMOTE GROWTH AND SURVIVAL OF MICROORGANISMS IN THE FOOD PROCESSING ENVIRONMENT. THIS PROPOSAL WILL DEVELOP AND VALIDATE INNOVATED TECHNOLOGIES FOR NON-AQUEOUS CLEANING AND SANITIZING. OIL-BASED ANTIMICROBIAL SOLUTIONS WILL BE DEVELOPED USING A VARIETY OF ORGANIC ACIDS AND WILL EVALUATE WATER-IN-OIL EMULSIONS TO DELIVER SANITIZING AGENTS. THE SUCCESSFUL FORMULATIONS WILL BE EVALUATED BASED UPON QUANTITATIVE VIABILITY ASSESSMENTS (PLATE COUNTS) AND QUALITATIVE ANALYSIS WITH MICROSCOPY TO EVALUATE ANTIMICROBIAL MECHANISM ON CELLULAR MEMBRANES, RESPIRATION, AND PROTEIN SYNTHESIS. AFTER SYSTEM DEVELOPMENT, WE WILL VALIDATE THE TREATMENTS UTILIZING A BENCHTOP SYSTEM TO MODEL CLEAN-IN-PLACE (CIP) FOR PEANUT BUTTER PROCESSING. THE LONG-TERM IMPACT OF THE PROPOSED RESEARCH IS THE HIGH POTENTIAL FOR TRANSLATION OF THE TECHNOLOGY TO THE FOOD INDUSTRY, WHICH HAS A HIGH NEED FOR NON-WATER, BASED CLEANING.
$413,093University Of Massachusetts · · FY2020 · National Institute of Food and Agriculture
Identifying a protective role for interferon lambda in tuberculosis
$413,002Joshua T. Mattila · University Of Pittsburgh At Pittsburgh · R21 · FY2025 · AI
Mechanisms of Lung Homeostasis by F box Proteins
$412,976Rama K Mallampalli · University Of Pittsburgh At Pittsburgh · R01 · FY2014 · HL
Biofilms and Immunity in Chronic Wounds
$412,969Daniel J Wozniak · Ohio State University · R01 · FY2015 · NR
Antimicrobials and Efflux Pumps in Staphylococcus aureus Infection
$412,915David C Hooper · Massachusetts Eye And Ear Infirmary · P01 · FY2011 · AI
Evaluation of Transperineal Biopsy under Local Anesthesia, a Novel approach to Decrease Post-Biopsy Infections and Improve Cancer Detection
$412,818Jim Hu · Weill Medical Coll Of Cornell Univ · R01 · FY2024 · CA
Gold Nanocrystal Antibiotics for the Treatment of Multidrug-resistant Gram Negati
$412,744Dan L. Feldheim · University Of Colorado · R01 · FY2015 · AI
Synthesis and Study of Amphotericin B Derivatives
$412,744Martin D Burke · University Of Illinois At Urbana-Champaign · R01 · FY2015 · GM
Keep It Clean for Kids: The KICK Project
$412,704Elaine Lucille Larson · Columbia University Health Sciences · R01 · FY2013 · HS
Improving Microbiome Science by Modeling the Measurement Process
$412,589Benjamin John Callahan · North Carolina State University Raleigh · R35 · FY2025 · GM
T-Cell response to CD1-restricted lipids in Tuberculosis
$412,575David Branch Moody · Brigham And Women'S Hospital · R01 · FY2010 · AI
Selenocyanate as a novel treatment of cystic fibrosis lung disease
$412,517Brian J Day · National Jewish Health · R01 · FY2019 · HL
Bifunctional Control of Yop Translocation by YopK
$412,500Melanie Marketon · Tufts University Boston · R01 · FY2017 · AI
Inducible epithelial resilience during pneumonia
$412,500Lee Quinton · Boston University Medical Campus · R01 · FY2018 · HL
PknG mediated tailoring Mycobacterium tuberculosis adaptive metabolism is required for the persister formation
$412,500Hyungjin Eoh · University Of Southern California · R56 · FY2019 · AI
Inducible epithelial resilience during pneumonia
$412,500Lee Quinton · Boston University Medical Campus · R01 · FY2020 · HL