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146,196 grants matching “diabetes”
SBIR Phase II: An omics-based computational drug design and discovery platform for next generation microbiome therapeutics
$1,623,498Mohammad Soheilypour · Nexilico, Inc. · · FY2023 · TIP
Biomarkers to Predict Patient Outcomes and Guide Therapies
$1,623,176Ann Cashion · National Institute Of Nursing Research · ZIA · FY2015 · NR
PARADOXICALLY, THE CONSUMPTION OF NON-CALORIC ARTIFICIAL SWEETENERS (NCASS) IS ASSOCIATED WITH AN INCREASED RISK OF WEIGHT GAIN, METABOLIC SYNDROME AND DIABETES. ALTHOUGH RECENT STUDIES SUGGEST THAT THESE NON-CALORIC FOOD ADDITIVES ARE PHYSIOLOGICALLY ACTIVE, THE MECHANISMS MEDIATING THEIR EFFECTS ARE UNCLEAR. THE ABSENCE OF MECHANISTIC UNDERSTANDING PREVENTS THE DEVELOPMENT OF INTERVENTIONS THAT WILL DIRECTLY EVALUATE THEIR INVOLVEMENT IN THE DEVELOPMENT OF OBESITY AND DIABETES. WE HAVE SHOWN THAT SUGARS AND NCASS ACTIVATE SWEET TASTE RECEPTORS PRESENT IN THE GUT AND STIMULATE HORMONAL SECRETIONS THAT AFFECTS HOW THE BODY ABSORBS NUTRIENTS. THE PROPOSED STUDIES INVESTIGATE HOW THE CONSUMPTION OF NUTRIENTS SUCH AS SIMPLE SUGARS AND NCASS CHANGES THE WAY THESE RECEPTORS OPERATE IN THE GUT. CONSEQUENTLY, THESE STUDIES WILL INCREASE OUR UNDERSTANDING OF NOVEL PATHWAYS THAT MODULATE NUTRIENT ABSORPTION AND UNVEIL POTENTIAL THERAPEUTIC TARGETS FOR THE MANAGEMENT OF TYPE 2 DIABETES.
$1,623,113Ohio State University, The · · FY2018 · National Institute of Food and Agriculture
BRFSS, THE DIABETES PREVENTION AND CONTROL PROGRAM, THE INDIANA TOBACCO PREVENTIO
$1,622,584Joellen Vrazel · Indiana State Department Of Health · U58 · FY2010 · DP
Dissecting the pathogenesis and outcomes of PSC using multi-omics by studying the exposome and genome
$1,622,560Konstantinos N Lazaridis · Mayo Clinic Rochester · RC2 · FY2018 · DK
Botanicals and Metabolic Syndrome
$1,622,369William T. Cefalu · Lsu Pennington Biomedical Research Ctr · P50 · FY2014 · AT
Insulin-Dependent Diabetes Mellitus
$1,621,946Abner L. Notkins · National Institute Of Dental & Craniofacial Research · ZIA · FY2011 · DE
The North American Mitochondrial Disease Consortium (NAMDC)
$1,621,474Michio Hirano · Columbia University Health Sciences · U54 · FY2021 · NS
National Institute of Diabetes and Digestive and Kidney Diseases ATLAS (D2K-ATLAS) Center as an accessible, comprehensive data portfolio for renal and genitourinary development and disease
$1,620,964Michael Todd Valerius · Brigham And Women'S Hospital · U24 · FY2022 · DK
ETIB Clinical Research Core
$1,620,926Ronald Gress · Division Of Basic Sciences - Nci · ZID · FY2014 · CA
Inherited Ocular Diseases
$1,620,806James F. Hejtmancik · National Eye Institute · ZIA · FY2022 · EY
National Institute of Diabetes and Digestive and Kidney Diseases ATLAS (D2K-ATLAS) Center as an accessible, comprehensive data portfolio for renal and genitourinary development and disease
$1,620,454Michael Todd Valerius · Brigham And Women'S Hospital · U24 · FY2023 · DK
Neutralizing the GBS hemolytic lipid toxin
$1,620,448Lakshmi Rajagopal · Seattle Children'S Hospital · R01 · FY2025 · AI
Chemoprevention of arsenic-induced skin cancer
$1,620,244Habibul Ahsan · University Of Chicago · R01 · FY2013 · CA
Resources to interpret genetic signals and multi-tissue mechanisms for type 2 diabetes and related traits
$1,620,238Karen L Mohlke · Univ Of North Carolina Chapel Hill · RC2 · FY2025 · DK
Identifying factors associated with prostate cancer progression and survival in African American men: The RESPOND Cohort
$1,620,203Christopher Alan Haiman · University Of Southern California · U01 · FY2024 · CA
Columbia Diabetes Research Center
$1,620,002Domenico Accili · Columbia University Health Sciences · P30 · FY2021 · DK
Columbia Diabetes Research Center
$1,620,002Domenico Accili · Columbia University Health Sciences · P30 · FY2022 · DK
Columbia Diabetes Research Center
$1,620,002Domenico Accili · Columbia University Health Sciences · P30 · FY2020 · DK
Columbia Diabetes Research Center
$1,620,002Domenico Accili · Columbia University Health Sciences · P30 · FY2019 · DK
AvanceIII 700MHz NMR spectrometer with cryogenic probe
$1,620,000James J Chou · Harvard Medical School · S10 · FY2010 · RR
The CHARGE Study Phase II: A Multifactorial Approach to Autism Etiology
$1,619,998Irva Hertz-Picciotto · University Of California At Davis · R01 · FY2022 · ES
The Impact of the Intrauterine and Early Childhood Environments on Neurocognitive and Metabolic Development in African American Youth: Focus on the Gut-Brain Axis
$1,619,862Anne Lang Dunlop · Emory University · UH3 · FY2021 · OD
The Impact of the Intrauterine and Early Childhood Environments on Neurocognitive and Metabolic Development in African American Youth: Focus on the Gut-Brain Axis
$1,619,862Anne Lang Dunlop · Emory University · UH3 · FY2022 · OD
The Impact of the Intrauterine and Early Childhood Environments on Neurocognitive and Metabolic Development in African American Youth: Focus on the Gut-Brain Axis
$1,619,862Anne Lang Dunlop · Emory University · UH3 · FY2020 · OD