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10,766 grants matching checkpoint inhibitor

Systemic delivery of an oncolytic adenovirus targeting TGFβ to enhance anti-PD-1 and anti-CTLA-4 therapy for triple negative breast cancer

$396,958
Weidong Xu · Endeavor Health Clinical Operations · R01 · FY2024 · CA

Double-Strand Break Sensing, Signaling, and Repair

$396,932
John A Tainer · University Of Calif-Lawrenc Berkeley Lab · P01 · FY2014 · CA

Induction of interferon response by chromatin damaging anti-cancer therapy

$396,881
Katerina V Gurova · Roswell Park Cancer Institute Corp · R01 · FY2025 · CA

Induction of interferon response by chromatin damaging anti-cancer therapy

$396,881
Katerina V Gurova · Roswell Park Cancer Institute Corp · R01 · FY2024 · CA

Overcoming Resistance Mechanisms to Anaplastic Lymphoma Kinase Inhibitors

$396,625
Aaron N Hata · Massachusetts General Hospital · R01 · FY2024 · CA

Targeting EZH2 in Germinal Center Derived B-Cell Lymphoma

$396,457
Ari M. Melnick · Weill Medical Coll Of Cornell Univ · R01 · FY2014 · CA

REGULATION AND ADAPTIVE MECHANISMS OF ONCOGENIC RAS/ERK SIGNALING

$396,453
Poulikos I Poulikakos · Icahn School Of Medicine At Mount Sinai · R01 · FY2024 · CA

Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicities

$396,432
Brent Allen Hanks · Duke University · R01 · FY2021 · CA

Covalent Protein Binders for Cancer Research and Therapy

$396,134
Lei Wang · University Of California, San Francisco · R01 · FY2023 · CA

Study of the IL-33-driven immune cell organization underpinning responses to immune checkpoint blockade cancer therapy

$396,116
Binfeng Lu · University Of Pittsburgh At Pittsburgh · R01 · FY2021 · CA

Development of IDO PET agents for immunotherapy

$396,007
Zibo Li · Univ Of North Carolina Chapel Hill · R01 · FY2022 · CA

Development of IDO PET agents for immunotherapy

$396,007
Zibo Li · Univ Of North Carolina Chapel Hill · R01 · FY2023 · CA

Mechanisms of Intestinal Tumorigenesis

$395,882
Vincent W. Yang · Emory University · R01 · FY2010 · CA

Targeting tumorigenic pathways in glioblastoma with oncolytic HSV

$395,770
Samuel D Rabkin · Massachusetts General Hospital · R01 · FY2021 · CA

Targeting tumorigenic pathways in glioblastoma with oncolytic HSV

$395,770
Samuel D Rabkin · Massachusetts General Hospital · R01 · FY2019 · CA

Targeting tumorigenic pathways in glioblastoma with oncolytic HSV

$395,770
Samuel D Rabkin · Massachusetts General Hospital · R01 · FY2020 · CA

Development of Therapeutic Cancer Vaccine

$395,738
Haifa Shen · Immunoq Therapeutics Inc. · R41 · FY2022 · CA

HCMV regulation of monocyte/macrophage host cell signaling in viral reactivation

$395,700
Andrew D Yurochko · Oregon Health & Science University · P01 · FY2022 · AI

Development of a tumor-retentive immunostimulant as adjunct therapy for solid tumor cancers

$395,595
Marcus Laird Forrest · Kinimmune, Inc. · R41 · FY2022 · CA

Targeting vulnerabilities of PPM1D-mutant gliomas

$395,535
Pratiti Bandopadhayay · Dana-Farber Cancer Inst · R37 · FY2023 · CA

Angiopoietin-2/Tie2 signaling regulation of liver metastasis in pancreatic neuroendocrine tumors

$395,516
Minah Kim · Columbia University Health Sciences · R37 · FY2024 · CA

Role of melanoma-PD-1 in cancer progression

$395,502
Tobias Schatton · Brigham And Women'S Hospital · R01 · FY2017 · CA

Role of melanoma-PD-1 in cancer progression

$395,502
Tobias Schatton · Brigham And Women'S Hospital · R01 · FY2021 · CA

Role of melanoma-PD-1 in cancer progression

$395,502
Tobias Schatton · Brigham And Women'S Hospital · R01 · FY2020 · CA

Role of melanoma-PD-1 in cancer progression

$395,501
Tobias Schatton · Brigham And Women'S Hospital · R01 · FY2018 · CA