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10,766 grants matching checkpoint inhibitor

Project 1: Targeting Tumor Phospholipase PLA2G10 for Cancer Immunotherapy

$411,417
Kurt A Schalper · Yale University · P50 · FY2025 · CA

Coordinating tumor differentiation and immune suppression with the metabolic state and treatment outcome

$411,278
Hans Ragnar Widlund · Brigham And Women'S Hospital · R01 · FY2017 · CA

Spatiotemporal control of insulin signaling by mitotic regulators

$411,250
Eunhee Choi · Columbia University Health Sciences · R01 · FY2022 · DK

Spatiotemporal control of insulin signaling by mitotic regulators

$411,250
Eunhee Choi · Columbia University Health Sciences · R01 · FY2023 · DK

Targeting Nucleotide Excision Repair Deficiency to Improve Bladder Sparing Treatment for Muscle Invasive Bladder Cancer

$411,213
Kent W Mouw · Dana-Farber Cancer Inst · R01 · FY2024 · CA

Defining the impact of intra-tumoral morphologic, immune and mutational heterogeneity in urothelial carcinoma

$410,835
Hikmat Al-Ahmadie · Sloan-Kettering Inst Can Research · R01 · FY2021 · CA

Defining the impact of intra-tumoral morphologic, immune and mutational heterogeneity in urothelial carcinoma

$410,835
Hikmat Al-Ahmadie · Sloan-Kettering Inst Can Research · R01 · FY2020 · CA

Defining the impact of intra-tumoral morphologic, immune and mutational heterogeneity in urothelial carcinoma

$410,835
Hikmat Al-Ahmadie · Sloan-Kettering Inst Can Research · R01 · FY2019 · CA

Targeting exosomal PDL1 to improve immunotherapy

$410,622
Wei Guo · Wistar Institute · P50 · FY2022 · CA

Epigenetic Reprogramming of T cell Exhaustion To Enhance Tumor Immunotherapy

$410,606
Benjamin Alan Youngblood · St. Jude Children'S Research Hospital · R01 · FY2021 · CA

Epigenetic Reprogramming of T cell Exhaustion To Enhance Tumor Immunotherapy

$410,606
Benjamin Alan Youngblood · St. Jude Children'S Research Hospital · R01 · FY2020 · CA

Targeting mechanisms of immune evasion in chemotherapy-induced senescent cells

$410,550
James Jackson · Tulane University Of Louisiana · R01 · FY2024 · CA

Using dietary glutamine supplementation for melanoma prevention and targeted therapy

$410,444
Mei Kong · University Of California-Irvine · R01 · FY2023 · CA

Project 4: Translation and preclinical studies of a personalized pancreas cancer vaccine

$410,431
William E Gillanders · Washington University · P50 · FY2020 · CA

Mechanisms of immunotherapy response and resistance in pancreatic ductal adenocarcinoma

$410,395
Ingunn Margarete Stromnes · University Of Minnesota · R01 · FY2024 · CA

Targeting head and neck cancer cells and the adverse tumor microenvironment with a novel small-molecule STAT3 inhibitor

$410,323
David John Tweardy · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

In situ radioimmunotherapy to maximize the engagement of conventional type 1 dendritic cells against non-T cell-inflamed tumors

$410,221
Fumito Ito · Roswell Park Cancer Institute Corp · R01 · FY2021 · CA

Engineering Nanomaterials to Prime Immunity

$410,177
James J. Moon · University Of Michigan At Ann Arbor · R01 · FY2021 · CA

Regulation of Zbtb44-Eomes complex in CD8+T cells and anti-tumor immunity

$410,082
Venuprasad K Poojary · Ut Southwestern Medical Center · R01 · FY2023 · AI

Regulation of Zbtb44-Eomes complex in CD8+T cells and anti-tumor immunity

$410,082
Venuprasad K Poojary · Ut Southwestern Medical Center · R01 · FY2024 · AI

Metabolic reprograming of fatty acid beta-oxidation to improve cancer immunotherapy

$410,049
Xiang-Yang Wang · Virginia Commonwealth University · R01 · FY2021 · CA

The coordination of cell size control and cell cycle regulation at developmental extremes

$410,000
Amanda A Amodeo · Dartmouth College · R35 · FY2024 · GM

The coordination of cell size control and cell cycle regulation at developmental extremes

$410,000
Amanda A Amodeo · Dartmouth College · R35 · FY2025 · GM

Project 4: Interrogating and harnessing age-related IFN signaling and innate immunity in HCC prevention and therapy

$409,560
Gen-Sheng Feng · Sanford Burnham Prebys Medical Discovery Institute · P01 · FY2024 · AG

MMS22L loss and PARP inhibition in prostate cancer

$409,463
Li Jia · Brigham And Women'S Hospital · R01 · FY2023 · CA