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10,766 grants matching checkpoint inhibitor

Translational Immunology

$425,301
Mark Gilbert · Division Of Basic Sciences - Nci · ZIA · FY2021 · CA

Epigenetic regulation of exhausted CD8 T cells via the miR-29a-TET2 axis

$425,216
Erietta Stelekati · University Of Miami School Of Medicine · R01 · FY2024 · AI

Using dietary glutamine supplementation for melanoma prevention and targeted therapy

$424,991
Mei Kong · University Of California-Irvine · R01 · FY2025 · CA

Project 4 :Using TME genetics and immunobiology to drive combination immunotherapies

$424,856
Elizabeth Marion Jaffee · Johns Hopkins University · P50 · FY2018 · CA

Interplay between LINE-1 retrotransposons, condensins, and IFN

$424,835
Michelle S Longworth · Cleveland Clinic Lerner Com-Cwru · R01 · FY2023 · GM

Analysis of the Replication Stress Response

$424,732
David K Cortez · Vanderbilt University · R01 · FY2022 · GM

Project 4: Therapeutic Targeting of Replication Stress Vulnerabilities in Small Cell Lung Cancer

$424,710
Lauren Averett Byers · Ut Southwestern Medical Center · P50 · FY2023 · CA

Project 4: Therapeutic Targeting of Replication Stress Vulnerabilities in Small Cell Lung Cancer

$424,709
Lauren Averett Byers · Ut Southwestern Medical Center · P50 · FY2022 · CA

Reprogramming the pancreatic tumor microenvironment with immunotherapy

$424,612
Lei Zheng · Johns Hopkins University · R01 · FY2015 · CA

Reprogramming the pancreatic tumor microenvironment with immunotherapy

$424,612
Lei Zheng · Johns Hopkins University · R01 · FY2016 · CA

Immune activation by necroptotic cell death

$424,373
Andrew Atwell Oberst · University Of Washington · R01 · FY2021 · CA

Targeted MEK inhibition to enhance immunotherapy in cholangiocarcinoma

$424,213
Gregory B. Lesinski · Emory University · R01 · FY2020 · CA

Genetic Mechanisms Controlling Kidney Cancer Immune Escape

$424,094
Haydn Kissick · Emory University · R01 · FY2024 · CA

Exploring novel therapeutic strategies for combinatory therapy to treat renal clear cell carcinomas

$424,015
Weizhou Zhang · University Of Florida · R01 · FY2024 · CA

Project 1: Targeted sequencing and clinicopathology to evaluate primary melanoma molecular subtypes and outcomes

$423,859
Marianne Berwick · University Of New Mexico Health Scis Ctr · P01 · FY2017 · CA

Clinical characterization of Kidney Injury Molecule-1 (KIM-1) as a Biomarker in Renal Cell Carcinoma

$423,811
David McDermott · Beth Israel Deaconess Medical Center · R01 · FY2023 · CA

Cooperation of SF3B1 mutations and ATM deletions in the pathogenesis of chronic lymphocytic leukemia

$423,784
Lili Wang · Beckman Research Institute/City Of Hope · R01 · FY2022 · CA

Targeting ER+ Breast Cancer Through Induced Viral Mimicry

$423,760
Charles H Spruck · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2024 · CA

KRAS inhibitors prime cancer cells for macrophage-mediated destruction

$423,760
Kipp A Weiskopf · Whitehead Institute For Biomedical Res · R01 · FY2024 · CA

Dissecting the influence of DNA damage response and homologous recombination deficiencies on tumor immunogenicity

$423,750
Robert M Samstein · Icahn School Of Medicine At Mount Sinai · DP5 · FY2021 · OD

Dissecting the influence of DNA damage response and homologous recombination deficiencies on tumor immunogenicity

$423,750
Robert M Samstein · Icahn School Of Medicine At Mount Sinai · DP5 · FY2023 · OD

Dissecting the influence of DNA damage response and homologous recombination deficiencies on tumor immunogenicity

$423,750
Robert M Samstein · Icahn School Of Medicine At Mount Sinai · DP5 · FY2019 · OD

Dissecting the influence of DNA damage response and homologous recombination deficiencies on tumor immunogenicity

$423,750
Robert M Samstein · Icahn School Of Medicine At Mount Sinai · DP5 · FY2020 · OD

Dissecting the influence of DNA damage response and homologous recombination deficiencies on tumor immunogenicity

$423,750
Robert M Samstein · Icahn School Of Medicine At Mount Sinai · DP5 · FY2022 · OD

Project 2

$423,518
David A Barbie · Dana-Farber Cancer Inst · P50 · FY2025 · CA