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10,766 grants matching checkpoint inhibitor

Targeting a PHGDH metabolic vulnerability in melanoma

$433,256
Florian Karreth · H. Lee Moffitt Cancer Ctr & Res Inst · R21 · FY2024 · CA

Role of histotripsy synergized CD40 signaling in the re-engineering of cold tumors

$433,173
Ashish Ranjan · Oklahoma State University Stillwater · R01 · FY2022 · CA

Lung Cancer Vaccine

$433,048
Nasser Khaled Altorki · Weill Medical Coll Of Cornell Univ · U54 · FY2025 · CA

Molecular Imaging and Metabolotheranostics of PDAC-Induced Cachexia

$432,889
Zaver M Bhujwalla · Johns Hopkins University · R01 · FY2025 · CA

AUGMENTING ANTITUMOR T-CELL RECRUITMENT AND ACTIVATION IN LOCALIZED NSCLC TUMORS TO IMPROVE CHECKPOINT INHIBITOR THERAPY

$432,500
Beckman Research Institute Of The City Of Hope · · FY2019 · Department of the Army

Targeting mechanisms of immune evasion in chemotherapy-induced senescent cells

$432,347
James Jackson · Tulane University Of Louisiana · R01 · FY2022 · CA

Project 3: Demethylation of HPV-associated head and neck cancer to trigger APOBEC synthetic lethality and enhance immune response

$432,279
Karen S Anderson · Yale University · P50 · FY2024 · DE

Understand & overcome resistance to PD-1

$432,274
Paul Nghiem · University Of Washington · P01 · FY2025 · CA

Epigenetic Synergy Between DNMT and EZH1/2 Inhibitors for Therapy in Solid Tumors

$432,171
Scott Rothbart · Coriell Institute For Medical Research · P50 · FY2021 · CA

Targeting Nucleotide Excision Repair Deficiency to Improve Bladder Sparing Treatment for Muscle Invasive Bladder Cancer

$432,128
Kent W Mouw · Dana-Farber Cancer Inst · R01 · FY2022 · CA

RasGRP3 and Protein Kinase D as therapeutic targets for Uveal Melanoma

$432,122
Xu Chen · University Of California, San Francisco · R01 · FY2024 · CA

Mechanisms of immunotherapy response and resistance in pancreatic ductal adenocarcinoma

$431,993
Ingunn Margarete Stromnes · University Of Minnesota · R01 · FY2025 · CA

Targeting LSD1 to prevent therapy-induced transdifferentiation in BRAF mutant colorectal cancer

$431,920
Heather M O'Hagan · Indiana University Indianapolis · R01 · FY2024 · CA

Targeting immune suppressive microenvironment in ATC

$431,902
James A Fagin · Sloan-Kettering Inst Can Research · R01 · FY2022 · CA

Targeting immune suppressive microenvironment in ATC

$431,902
James A Fagin · Sloan-Kettering Inst Can Research · R01 · FY2023 · CA

ALDH Inhibition as Modulator of Tumor Immunobiology

$431,843
Ronald J Buckanovich · Magee-Women'S Res Inst And Foundation · R01 · FY2022 · CA

A Novel Adenoviral-Permissive, Immunocompetent Hamster Model to Evaluate Oncolytic Adenoviral Therapy for Glioblastoma

$431,749
Frederick F Lang · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

RCAN 1.4 metastasis suppressor in thyroid cancer

$431,712
Matthew D Ringel · Ohio State University · R01 · FY2024 · CA

A Mouse Model to Assess Long Term Immunotherapy-related Adverse Effects in Children

$431,631
Pan Zheng · University Of Maryland Baltimore · R01 · FY2018 · CA

Targeting Gq pathway in uveal melanoma

$431,571
Xu Chen · University Of California, San Francisco · R01 · FY2024 · CA

Targeting HMGA1 Tumor-Stromal Networks in Pancreatic Carcinogenesis

$431,561
Linda M S Resar · Johns Hopkins University · R01 · FY2024 · CA

Probing cellular, molecular and biomechanical barriers to immunotherapy in the tumor microenvironment with organotypic in vitro models of the tumor-lympho-immune interface

$431,440
Melody A Swartz · University Of Chicago · R01 · FY2023 · CA

Probing cellular, molecular and biomechanical barriers to immunotherapy in the tumor microenvironment with organotypic in vitro models of the tumor-lympho-immune interface

$431,440
Melody A Swartz · University Of Chicago · R01 · FY2022 · CA

Immune activation by necroptotic cell death

$431,384
Andrew Atwell Oberst · University Of Washington · R01 · FY2020 · CA

Augmenting Anti-Tumor Immunity Using Radiation in the Setting of DNA Repair Defects

$431,284
Simona Shaitelman · University Of Tx Md Anderson Can Ctr · R21 · FY2020 · CA