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30,917 grants matching tumor microenvironment

Engineering mRNA encapsulated extracellular vesicles for in vivo chimeric antigen receptor macrophage therapy for glioblastoma

$645,873
Wen Jiang · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · CA

Engineering mRNA encapsulated extracellular vesicles for in vivo chimeric antigen receptor macrophage therapy for glioblastoma

$645,873
Wen Jiang · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

Systems Modeling of Tumor Heterogeneity and Therapy Response in Colorectal Cancer

$645,756
Fiona Ginty · General Electric Global Research Ctr · R01 · FY2021 · CA

Targeting complement to enhance antitumor immunity and control malignant effusions in patients with recurrent epithelial ovarian cancer

$645,738
Emese Zsiros · Roswell Park Cancer Institute Corp · R01 · FY2023 · CA

Designer extracellular vesicles for cancer therapy

$645,726
Xiaowei Xu · University Of Pennsylvania · R01 · FY2025 · CA

(PQC5) Detecting small clusters of tumor cells with a PTPmu probe

$645,638
Susann M Brady-Kalnay · Case Western Reserve University · R01 · FY2013 · CA

Multiscale systems biology modeling to exploit tumor-stromal metabolic crosstalk in colorectal cancer

$645,632
Stacey Deleria Finley · University Of Southern California · U01 · FY2021 · CA

Develop lung-targeted synthetic lipid nanoparticles for mRNA medicine treating pulmonary lymphangioleiomyomatosis

$645,566
Qiaobing Xu · Tufts University Medford · R01 · FY2025 · HL

Variation in tumor-associated immune profiles and colorectal cancer outcomes

$645,534
Stephanie L. Schmit · Cleveland Clinic Lerner Com-Cwru · R01 · FY2024 · CA

Pacritinib in rel/refr T-cell lymphomas

$645,497
Ryan A Wilcox · University Of Michigan At Ann Arbor · R01 · FY2021 · CA

Generation of tumor specific immunity in canine osteosarcoma through dendritic cell hyperactivation

$645,473
Cheryl A London · Tufts University Boston · U01 · FY2022 · CA

The linkage between Race, Kaiso and the tumor microenvironment in breast cancer health disparities

$645,464
Kevin L. Gardner · Columbia University Health Sciences · R01 · FY2023 · CA

Decoding tumor metabolic and immunologic interactions driving racial disparity in African American patients with bladder cancer.

$645,401
Nagireddy Putluri · Baylor College Of Medicine · R01 · FY2023 · CA

A phase I study of RNA-lipid particle vaccines for newly-diagnosed glioblastoma, IND19304 08/21/2020

$645,379
Elias Sayour · University Of Florida · R01 · FY2025 · FD

Mechanism of acid signaling in bone organ metastases on tumor and myeloid cell evolution towards immune suppression and tumor progression

$645,323
Katherine Nelson Weilbaecher · Washington University · R01 · FY2025 · CA

Immunoregulatory role of lung-resident club cell factors in lung cancer

$645,197
Vivek Mittal · Weill Medical Coll Of Cornell Univ · R01 · FY2024 · CA

A biophysical stromal basis for radiation sensitivity in ductal carcinoma in situ

$645,033
Catherine C Park · University Of California, San Francisco · R01 · FY2015 · CA

Molecular Determinants and Therapeutic Consequences of Immune Heterogeneity in Cancer

$644,986
Robert H Vonderheide · University Of Pennsylvania · R01 · FY2022 · CA

Using genetically engineered mouse models of brain tumors to develop therapeutic nanoparticles & biomaterials

$644,838
Eric C Holland · Fred Hutchinson Cancer Research Center · R01 · FY2017 · CA

Quantitative Multimodal Image Guidance for Improved Liver Cancer Treatment

$644,766
James S Duncan · Yale University · R01 · FY2017 · CA

Targeting posttranslational modifications of CD73 in TNBCs

$644,746
Yong Wan · Emory University · R01 · FY2025 · CA

Elucidate how dendritic cells affect T cells' function in the TME of non-small cell lung cancer

$644,606
Chen Zhao · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA

Study the interactions between alveolar macrophages and T cells in non-small cell lung cancer

$644,606
Chen Zhao · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA

Epigenomic Reprogramming in Patient Derived Models of Colorectal Cancer

$644,430
Xiling Shen · Duke University · U01 · FY2020 · CA

(PQ5) Effect of HIV infection on viral and host gene expression and antitumor immunity in Kaposi Sarcoma in Africa

$644,421
Edus Houston Warren · Fred Hutchinson Cancer Research Center · R01 · FY2017 · CA