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10,766 grants matching checkpoint inhibitor

Targeting Gq pathway in uveal melanoma

$445,160
Xu Chen · University Of California, San Francisco · R01 · FY2023 · CA

CDK4/6 inhibition during CD8 T cell priming potentiates memory formation in mice and humans

$445,000
Stephanie Dougan · Dana-Farber Cancer Inst · R01 · FY2022 · AI

CDK4/6 inhibition during CD8 T cell priming potentiates memory formation in mice and humans

$445,000
Stephanie Dougan · Dana-Farber Cancer Inst · R01 · FY2024 · AI

CDK4/6 inhibition during CD8 T cell priming potentiates memory formation in mice and humans

$445,000
Stephanie Dougan · Dana-Farber Cancer Inst · R01 · FY2025 · AI

CDK4/6 inhibition during CD8 T cell priming potentiates memory formation in mice and humans

$445,000
Stephanie Dougan · Dana-Farber Cancer Inst · R01 · FY2023 · AI

CDK4/6 inhibition during CD8 T cell priming potentiates memory formation in mice and humans

$445,000
Stephanie Dougan · Dana-Farber Cancer Inst · R01 · FY2021 · AI

Co-regulation of p53 and PD-L1 by the VPRBP-USP2 axis in transcription and ubiquitylation

$444,968
Wei Gu · Columbia University Health Sciences · R01 · FY2024 · CA

Targeting exosomal PDL1 to improve immunotherapy

$444,750
Wei Guo · Wistar Institute · P50 · FY2025 · CA

The Role of Epithelial-Mesenchymal Transition in Re-Wiring KRAS Mutant Lung Cancer

$444,653
Don Lynn Gibbons · University Of Tx Md Anderson Can Ctr · R37 · FY2021 · CA

Targeting Epigenomic Regulators at the Replication Fork in PDAC

$444,584
Gwen Lomberk · Medical College Of Wisconsin · R01 · FY2023 · CA

Spherical Nucleic Acid nano-architectures as first-in-class cGAS agonists for the immunotherapeutic treatment of Glioblastoma.

$444,533
Alexander H. Stegh · Washington University · R01 · FY2024 · CA

An innate immune checkpoint in cancer immunotherapy

$444,441
Carla Rothlin · Yale University · R01 · FY2019 · CA

Epigenetic Regulation of Head and Neck Cancer Immune Evasion

$444,406
Chao Lu · Columbia University Health Sciences · R01 · FY2024 · DE

Photodynamic therapy with prior inhibition of epidermal growth factor receptor to stimulate antitumor innate immune response

$444,397
Theresa M Busch · University Of Pennsylvania · R01 · FY2019 · CA

Photodynamic therapy with prior inhibition of epidermal growth factor receptor to stimulate antitumor innate immune response

$444,397
Theresa M Busch · University Of Pennsylvania · R01 · FY2020 · CA

Mutational signature analysis: methods and applications to the clinic

$444,343
Peter Park · Harvard Medical School · R01 · FY2023 · CA

PI3K/PTEN/Akt signaling and the genesis of cancer

$444,339
Nissim Hay · University Of Illinois At Chicago · R01 · FY2024 · CA

A novel strategy to overcome drug resistance in cancer

$444,318
Aimee L Edinger · University Of California-Irvine · R01 · FY2024 · CA

Project 2: Deciphering the Dynamic Evolution of the Tumor-Immune Interface

$444,255
Stefani Spranger · Massachusetts Institute Of Technology · U54 · FY2025 · CA

Understanding and exploiting novel therapeutic vulnerabilities of RIT1-driven lung cancer

$444,008
Alice Berger · Fred Hutchinson Cancer Center · R37 · FY2024 · CA

Reprogramming the Tumor Microenvironment in Ovarian Cancer

$443,654
David D Schlaepfer · University Of California, San Diego · R01 · FY2020 · CA

Targeting MAL2-mediated endocytosis to enhance tumor cell antigen presentation

$443,556
Xinna Zhang · Indiana University Indianapolis · R01 · FY2024 · CA

Spherical Nucleic Acid nano-architectures as first-in-class cGAS agonists for the immunotherapeutic treatment of Glioblastoma.

$443,482
Alexander H. Stegh · Washington University · R01 · FY2022 · CA

RCAN 1.4 metastasis suppressor in thyroid cancer

$443,434
Matthew D Ringel · Ohio State University · R01 · FY2022 · CA

Project 3: The AMPK Autophagy Pathway as a Metabolic Liability in Pancratic Ductal Adenocarcinoma

$443,412
Reuben J Shaw · Salk Institute For Biological Studies · P01 · FY2024 · CA