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10,766 grants matching checkpoint inhibitor

Expanding the tumor antigen landscape and maintaining APCs in a T cell-activating state to restore tumor immunity

$473,680
Eduardo Davila · University Of Colorado Denver · R01 · FY2025 · CA

Reversing cancer immunosuppression using attenuated Listeria monocytogenes

$473,641
Daniel A Portnoy · University Of California Berkeley · R01 · FY2024 · CA

Reversing cancer immunosuppression using attenuated Listeria monocytogenes

$473,641
Daniel A Portnoy · University Of California Berkeley · R01 · FY2025 · CA

FEEDBACK CONTROL OF THE CELL CYCLE

$473,631
Harvard University · R37 · FY2001 · GM

Targeting a phosphatidylserine/TAM receptor/PD-L1 axis as a vulnerability in cancer

$473,620
Raymond B Birge · Rutgers Biomedical And Health Sciences · R01 · FY2023 · CA

A modular cell therapy platform for controlling immunological tolerance

$473,515
Nathan Edward Reticker-Flynn · Stanford University · DP2 · FY2024 · AI

A modular cell therapy platform for controlling immunological tolerance

$473,515
Nathan Edward Reticker-Flynn · Stanford University · DP2 · FY2025 · AI

Targeting a phosphatidylserine/TAM receptor/PD-L1 axis as a vulnerability in cancer

$473,506
Raymond B Birge · Rutgers Biomedical And Health Sciences · R01 · FY2025 · CA

Understanding the impact of chemotherapy on breast cancer metastasis and immune function in the liver

$473,350
Sandra S McAllister · Brigham And Women'S Hospital · R01 · FY2024 · CA

Preclinical Development of First-in-Class NDUFS7 Antagonists for the Treatment of Pancreatic Cancer

$473,270
Nouri Neamati · University Of Michigan At Ann Arbor · R01 · FY2022 · CA

An integrated polymeric carrier for subunit cancer vaccines

$473,251
Suzie H Pun · University Of Washington · R01 · FY2023 · CA

Re-wiring PDAC Tumor Immunity Through Dendritic Cells

$473,084
David G Denardo · Washington University · R01 · FY2025 · CA

Project 4: Therapeutic Targeting of Replication Stress Vulnerabilities in Small Cell Lung Cancer

$472,890
Lauren Averett Byers · Ut Southwestern Medical Center · P50 · FY2020 · CA

Targeting Epigenomic Regulators at the Replication Fork in PDAC

$472,850
Gwen Lomberk · Medical College Of Wisconsin · R01 · FY2021 · CA

Overcoming the blood-brain barrier with nanoparticle vaccines against gliomas

$472,806
Elias Sayour · University Of Florida · R37 · FY2021 · CA

Therapeutic Targeting of Macrophage PI3Kgamma in HNSCC

$472,763
Judith A. Varner · University Of California, San Diego · R01 · FY2021 · CA

Elucidating the Role of the Tumor Suppressor KEAP1 in Antitumor Immunity

$472,730
Antonio Marzio · Weill Medical Coll Of Cornell Univ · R01 · FY2025 · CA

Project 2: Targeting signaling networks to overcome therapeutic resistance in pancreatic cancer

$472,698
Tony R. Hunter · Salk Institute For Biological Studies · P01 · FY2024 · CA

Preclinical Development of First-in-Class NDUFS7 Antagonists for the Treatment of Pancreatic Cancer

$472,491
Nouri Neamati · University Of Michigan At Ann Arbor · R01 · FY2025 · CA

Preclinical and clinical characterization of DNMT inhibitors +/- standard chemoimmunotherapy in TNBC

$472,447
Liewei Wang · Mayo Clinic Rochester · R01 · FY2025 · CA

PAIRS: Validating telomerase reverse transcriptase (TERT) as an intrinsic vulnerability toward sensitizing cancer to radiation

$472,393
Stephen J. Kron · University Of Chicago · R01 · FY2023 · CA

Stroma penetrating and immune modulating nanoparticles for image-guided therapy of pancreatic cancer

$472,215
Lily Yang · Emory University · R01 · FY2025 · CA

Cancer Immunotherapy Clinical Trials

$472,182
Julius Strauss · Division Of Basic Sciences - Nci · ZIA · FY2019 · CA

Breast and Other Carcinoma Clinical Trials Using Immunotherapies

$472,182
Margaret Gatti-Mays · Division Of Basic Sciences - Nci · ZIA · FY2019 · CA

Ascorbic acid as a pharmacologic agent in disease treatment

$472,165
Mark A Levine · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2021 · DK