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10,766 grants matching checkpoint inhibitor

Project 2: Synthetic Lethal Therapy for HPV-Negative Head and Neck Cancer

$480,846
Barbara Burtness · Yale University · P50 · FY2023 · DE

Targeting Lysosomal Vulnerabilities in Renal Pathogenesis

$480,833
Steffan T Nawrocki · University Of Arizona · R01 · FY2025 · CA

Targeting Lysosomal Vulnerabilities in Renal Pathogenesis

$480,833
Steffan T Nawrocki · University Of Arizona · R01 · FY2022 · CA

A novel strategy to overcome drug resistance in cancer

$480,820
Aimee L Edinger · University Of California-Irvine · R01 · FY2023 · CA

Vascular image-guided optimization of response (VIGOR) to therapy in kidney cancer

$480,760
Ralph P Mason · Ut Southwestern Medical Center · R01 · FY2023 · CA

SMART ASSAYS FOR LIGANDS TO STUDY AND TREAT CANCER

$480,736
Harvard University (Medical School) · P01 · FY2000 · CA

Preclinical-Clinical Trials Collaboration to effectively advance new combination therapies for malignant peripheral nerve sheath tumors

$480,710
Karen M Cichowski · Brigham And Women'S Hospital · U01 · FY2022 · CA

Next-Generation Antibody Discovery and Development Technology

$480,577
David Scott Johnson · Gigagen, Inc. · R44 · FY2017 · CA

Investigating multifactorial beta-catenin activation in hepatocellular cancers

$480,413
Xin Chen · University Of Hawaii At Manoa · R01 · FY2023 · CA

Inhibition of wild-type IDH1 as a ferroptosis-inducing therapeutic approach for the treatment of malignant glioma.

$480,412
Alexander H. Stegh · Washington University · R01 · FY2025 · NS

Targeting replication stress signaling to overcome immune evasion in small cell lung cancer

$480,259
Triparna Sen · Icahn School Of Medicine At Mount Sinai · R01 · FY2023 · CA

Defining the role of NF1 and SPRED1 loss in melanoma

$480,247
Iwei Yeh · University Of California, San Francisco · R37 · FY2024 · CA

Epigenetic Synergy Between DNMT and EZH1/2 Inhibitors for Therapy in Solid Tumors

$480,188
Scott Rothbart · Coriell Institute For Medical Research · P50 · FY2025 · CA

Targeting the LIFR-LCN2 pathway to improve liver cancer therapy

$480,131
Li Ma · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · CA

Targeting the LIFR-LCN2 pathway to improve liver cancer therapy

$480,131
Li Ma · University Of Tx Md Anderson Can Ctr · R01 · FY2023 · CA

Solid Phase Microextraction as a New Tool for Quantifying Antibody Drugs in Breast Cancer and Building PK-PD models

$480,000
Florin Marcel Musteata · Albany College Of Pharmacy · R15 · FY2024 · CA

Systems analysis of mechanisms driving response to immunotherapy in clear cell cancers

$479,806
Andrew J. Gentles · Stanford University · U01 · FY2024 · CA

Mechanistic analyses of a novel RNA polymerase I transcription checkpoint

$479,662
Marikki Laiho · Johns Hopkins University · R01 · FY2019 · GM

Project 1 Targeting the PI3K Pathway to Overcome Resistance to Immunotherapy in Melanomas with Loss of PTEN

$479,648
Michael Davies · University Of Tx Md Anderson Can Ctr · P50 · FY2023 · CA

Mechanistic analyses of a novel RNA polymerase I transcription checkpoint

$479,517
Marikki Laiho · Johns Hopkins University · R01 · FY2020 · GM

Determinants of immunotherapy response in NASH-Hepatocellular carcinoma

$479,492
Josep M Llovet · Icahn School Of Medicine At Mount Sinai · R01 · FY2025 · CA

Drug Mechanism of Action-based targeting of tumor subpopulations

$479,435
Andrea Califano · Columbia University Health Sciences · U54 · FY2023 · CA

Eukaryotic Chromosome Replication

$479,430
Bonita J Brewer · University Of Washington · R01 · FY2007 · GM

Melanoma: Metabolic Biomarkers of Response to Targeted Therapy

$479,380
Jerry D Glickson · University Of Pennsylvania · R01 · FY2021 · CA

Randomized Trial of Stepped Palliative Care versus Early Integrated Palliative Care in Patients with Advanced Lung Cancer

$479,376
Jennifer Temel · Massachusetts General Hospital · R01 · FY2020 · CA