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17,828 grants matching crispr

Adipose tissue-colorectal tumor cross-talk: new targets for breaking the obesity-cancer link

$677,102
Cornelia M Ulrich · University Of Utah · R01 · FY2021 · CA

Discovery and characterization of clinically actionable germline mutations in DNA damage repair (DDR) pathway genes in lung cancer

$676,729
Semanti Mukherjee · Sloan-Kettering Inst Can Research · R37 · FY2024 · CA

Exploiting cell fate transition to overcome radiation resistance in glioblastoma

$676,623
Erik Sulman · New York University School Of Medicine · R01 · FY2025 · CA

In vivo delivery of engineered tRNAs for suppression of nonsense mutations

$676,428
John D. Lueck · University Of Rochester · R01 · FY2023 · HL

A high-performance and versatile technology for precision microbiome engineering

$676,224
Harris H Wang · Columbia University Health Sciences · R01 · FY2022 · EB

Nutrigenomics of Intestinal Vitamin D Action

$676,221
Sylvia S Christakos · Rutgers Biomedical And Health Sciences · R01 · FY2025 · DK

Modeling Tyrosine Kinase Inhibitor-Induced Vascular Dysfunction Using Human iPSCs

$675,989
Joseph C Wu · Stanford University · R01 · FY2023 · HL

PDGFD regulates a transcriptional network to modulate smooth muscle cell transition and coronary artery disease risk

$675,980
Thomas None Quertermous · Stanford University · R01 · FY2021 · HL

Directing fate, subtype identity and survival in human pluripotent-derived midbrain dopamine neurons

$675,698
Lorenz P. Studer · Sloan-Kettering Inst Can Research · R01 · FY2021 · NS

New tools for quantitative non-invasive recording of biochemical signals

$675,594
Nathan Christopher Shaner · University Of California, San Diego · R01 · FY2024 · CA

Cellular dissection of herpes simplex encephalitis with iPS cells

$675,297
Jean-Laurent Casanova · Rockefeller University · R01 · FY2018 · NS

Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling

$675,266
Joseph C Wu · Stanford University · R01 · FY2025 · HL

Integrative Characterization on the function of COPD GWAS gene, HHIP

$675,259
Anny Xiaobo Zhou · Brigham And Women'S Hospital · R01 · FY2020 · HL

Corrective editing to treat phenylketonuria

$675,157
Xiao Wang · University Of Pennsylvania · R01 · FY2024 · HD

Corrective editing to treat phenylketonuria

$675,157
Xiao Wang · University Of Pennsylvania · R01 · FY2025 · HD

PDGFD regulates a transcriptional network to modulate smooth muscle cell transition and coronary artery disease risk

$675,112
Thomas None Quertermous · Stanford University · R01 · FY2023 · HL

PDGFD regulates a transcriptional network to modulate smooth muscle cell transition and coronary artery disease risk

$675,112
Thomas None Quertermous · Stanford University · R01 · FY2022 · HL

Craniofacial Developmental Dynamics

$674,880
Kenneth Yamada · National Institute Of Dental & Craniofacial Research · ZIA · FY2023 · DE

The role of AU-rich element binding proteins in shaping target mRNA expression

$674,784
Markus Hafner · National Institute Of Arthritis And Musculoskeletal And Skin Diseases · ZIA · FY2023 · AR

CRISPRa-based rescue of sensorimotor deficits in the Scn2a+/- mouse model of autism spectrum disorder

$674,656
Kevin J Bender · University Of California, San Francisco · R01 · FY2024 · MH

From Obesity GWAS to therapeutic targets

$674,421
Christian Vaisse · University Of California, San Francisco · R01 · FY2024 · DK

Protein kinase C and lung carcinogenesis

$674,373
Marcelo Gabriel Kazanietz · University Of Pennsylvania · R01 · FY2023 · CA

Project 2: Impact of H1/H2 haplotypes on cellular disease-associated phenotypes driven by FTD-causing MAPT mutations

$673,965
Daniel H Geschwind · Icahn School Of Medicine At Mount Sinai · U54 · FY2025 · NS

Effects of Interferon on primate lentiviruses

$673,658
Theodora Hatziioannou · Rockefeller University · R01 · FY2025 · AI

Targeting parasite-host communication to combat liver fluke-induced bile duct cancer

$673,652
Paul J Brindley · George Washington University · R01 · FY2018 · CA