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17,828 grants matching crispr

Novel recombinant Rotavirus vaccine utilizing the probiotic microorganism Lactobacillus acidophilus

$679,126
Gregg A Dean · Colorado State University · R01 · FY2022 · AI

Epigenetic mechanisms of sustained transcription across cocaine abstinence

$679,084
Elizabeth A Heller · University Of Pennsylvania · R01 · FY2021 · DA

Platform to accurately recapitulate and perturb cortical development and morphogenesis in vitro

$679,072
Sharad Ramanathan · Harvard University · R01 · FY2025 · MH

Next generation massively multiplexed combinatorial genetic screens

$678,814
Prashant Mali · University Of California, San Diego · R01 · FY2025 · HG

Structure function relationships from deep mutational scanning in human cardiomyopathy

$678,670
Euan A Ashley · Stanford University · R01 · FY2023 · HL

Mapping Molecular Pathways that Control Prion Metabolism

$678,442
Surachai Supattapone · Dartmouth College · R37 · FY2025 · NS

Mapping Molecular Pathways that Control Prion Metabolism

$678,442
Surachai Supattapone · Dartmouth College · R37 · FY2023 · NS

Functional Characterization and Development of Therapeutic Paradigms for DNA Damage Repair (DDR)-deficient Lethal Prostate Cancer

$678,271
Goutam Chakraborty · Icahn School Of Medicine At Mount Sinai · R01 · FY2024 · CA

Rational optimization of combinatorial therapies for the treatment of rare cystic fibrosis variants

$678,226
Jonathan Patrick Schlebach · Purdue University · R01 · FY2024 · HL

Kallikrein-PAR interactions in skin inflammation

$678,165
Nicole Leanne Ward · Case Western Reserve University · R01 · FY2020 · AR

Pro-Inflammatory Stem Cell Variants in Cystic Fibrosis

$678,096
Frank D. McKeon · University Of Houston · R01 · FY2025 · HL

Pro-Inflammatory Stem Cell Variants in Cystic Fibrosis

$678,096
Frank D. McKeon · University Of Houston · R01 · FY2023 · HL

Broad-spectrum HIV gene editing strategies in peripheral and brain reservoirs

$678,047
Brian Wigdahl · Drexel University · R01 · FY2025 · MH

Targeting p38 gamma signaling to advance Cutaneous T Cell Lymphoma Therapy

$678,014
Steven Terry Rosen · Beckman Research Institute/City Of Hope · R01 · FY2023 · CA

Targeting p38 gamma signaling to advance Cutaneous T Cell Lymphoma Therapy

$678,014
Steven Terry Rosen · Beckman Research Institute/City Of Hope · R01 · FY2022 · CA

Mechanisms and targeting of aberrant Gas activation in myeloid neoplasms

$677,959
Eirini Papapetrou · Icahn School Of Medicine At Mount Sinai · R01 · FY2025 · CA

Mechanisms of Toxicity Induced by EWS/FLI1 Overdose in Ewing Sarcoma

$677,914
Kimberly Stegmaier · Dana-Farber Cancer Inst · R01 · FY2024 · CA

Self-Peptides Bound to MHC Class II in T Cell Selection

$677,758
Alexander Y. Rudensky · Sloan-Kettering Inst Can Research · R01 · FY2025 · AI

Structure function relationships from deep mutational scanning in human cardiomyopathy

$677,725
Euan A Ashley · Stanford University · R01 · FY2022 · HL

Proinflammatory B Cells Defined by TIM-4 in the Alloimmune Response

$677,724
David M Rothstein · University Of Pittsburgh At Pittsburgh · R01 · FY2024 · AI

Structural and functional studies of colibactin

$677,571
Seth B. Herzon · Yale University · R01 · FY2023 · CA

Project 2: Molecular Modulation of Chromatin and Nuclear Structure in Cancer

$677,567
Jonathan D. Licht · Northwestern University At Chicago · U54 · FY2018 · CA

Genome Editing of Human iPSCs to Study Inherited Hypertrophic Cardiomyopathy

$677,504
Joseph C Wu · Stanford University · R01 · FY2020 · HL

Generation of Hematopoietic Stem and Progenitor Cells from Human iPSCs

$677,161
Andre Larochelle · National Heart, Lung, And Blood Institute · ZIA · FY2019 · HL

Defining molecular mechanisms by which stimulant evoked dopamine drives inflammation and neuronal dysfunction in neuroHIV

$677,147
Peter Jesse Gaskill · Drexel University · R33 · FY2025 · DA