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17,828 grants matching crispr

Decoding the Cullin-5 complex to engineer therapeutic T cells with durable effector function

$680,598
Julia C Carnevale · University Of California, San Francisco · R01 · FY2025 · CA

Development of 3D Alveolar Tissue Models, CRISPR-editing and Microbiota-immune Response Assay Platforms for Deciphering Human Lung Immunity

$680,574
Derya Unutmaz · Jackson Laboratory · U19 · FY2019 · AI

Elucidate the landscape of druggable targets for eliminating cancer persister cells

$680,507
Steven J Altschuler · University Of California, San Francisco · R01 · FY2025 · CA

Cellular dissection of herpes simplex encephalitis with iPS cells

$680,371
Jean-Laurent Casanova · Rockefeller University · R01 · FY2017 · NS

Genomics and Pharmacogenomics of Symptoms in Asthma

$680,342
Kelan G Tantisira · University Of California, San Diego · R01 · FY2024 · HL

BMPR2, Monocytes and Macrophages in Pulmonary Artery Hypertension

$680,174
Marlene Rabinovitch · Stanford University · R01 · FY2024 · HL

Epigenetic mechanisms of sustained transcription across cocaine abstinence

$680,143
Elizabeth A Heller · University Of Pennsylvania · R01 · FY2024 · DA

Epigenetic mechanisms of sustained transcription across cocaine abstinence

$680,143
Elizabeth A Heller · University Of Pennsylvania · R01 · FY2023 · DA

Molecular Regulation of Stem Cell Aging

$680,096
Anne Brunet · University Of California Los Angeles · P01 · FY2024 · AG

Mechanism of cell uptake for pathogenic tau seeds

$680,077
Marc I Diamond · Ut Southwestern Medical Center · R01 · FY2023 · AG

Mechanism of cell uptake for pathogenic tau seeds

$680,077
Marc I Diamond · Ut Southwestern Medical Center · R01 · FY2024 · AG

Mechanism of cell uptake for pathogenic tau seeds

$680,077
Marc I Diamond · Ut Southwestern Medical Center · R01 · FY2022 · AG

Quinine polymer beacons for probing encapsulation and cellular delivery of CRISPR-Cas9

$679,804
Theresa M Reineke · University Of Minnesota-Twin Cities · · FY2019 · MPS

In Vivo RNA-Mediated Gene Editing of Hemophilia A

$679,764
Drew Weissman · University Of Pennsylvania · R01 · FY2019 · HL

Target Host Epigenetic Regulation of HIV Proviruses to Reinforce Viral Deep Latency in Microglia

$679,675
Jian Zhu · Ohio State University · R01 · FY2025 · MH

Centrosome Maturation and Duplication in the C. elegans Embryo

$679,664
Kevin O'Connell · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2017 · DK

Improving the Safety of Genome Editing With Human Kidney Organoids

$679,632
Benjamin Solomon Freedman · University Of Washington · U01 · FY2020 · DK

A novel mechanism of virulence control in Porphyromonas gingivalis

$679,618
Jorge Frias-Lopez · University Of Florida · R01 · FY2023 · DE

Evaluating Pathways Involved in Melanoma Initiation

$679,604
Leonard I Zon · Boston Children'S Hospital · R01 · FY2025 · CA

Identification and characterization of inflammatory bowel disease causal variants

$679,492
Hailiang Huang · Massachusetts General Hospital · R01 · FY2025 · DK

Defining gene regulatory networks driving cortical evolution and brain development

$679,388
Luis De La Torre-Ubieta · University Of California Los Angeles · R01 · FY2023 · MH

Mapping, modeling, and manipulating 3D contacts in vascular cells to connect risk variants to disease genes

$679,363
Jesse M Engreitz · Stanford University · R01 · FY2024 · HL

A network approach to interrogate cellular plasticity and drug resistance in cancer

$679,232
Rosemary J Akhurst · University Of California, San Francisco · R01 · FY2025 · CA

AAV Gene Therapy for Sialidosis: from Mice to IND

$679,207
Heather L Gray-Edwards · Univ Of Massachusetts Med Sch Worcester · R01 · FY2024 · NS

Structure function relationships from deep mutational scanning in human cardiomyopathy

$679,148
Euan A Ashley · Stanford University · R01 · FY2021 · HL