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10,766 grants matching checkpoint inhibitor

Dissecting the role of Notch signaling in the pancreatic cancer microenvironment.

$495,740
Marina Pasca Di Magliano · University Of Michigan At Ann Arbor · R01 · FY2024 · CA

Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes

$495,583
Robert L Ferris · University Of Pittsburgh At Pittsburgh · R01 · FY2017 · CA

Tackling Treg mediated resistance to radiation and anti-PDL1 in HNSCCs

$495,520
Sana D Karam · University Of Colorado Denver · R01 · FY2024 · DE

Project 1: Evaluating stem-like T cells and improving efficacy of checkpoint inhibitors in NSCLC

$495,197
Rafi Ahmed · Emory University · P50 · FY2020 · CA

Validation of, and therapeutic evaluation in ovarian cancer GEM models

$495,160
Shyam Sharan · Division Of Basic Sciences - Nci · ZIA · FY2016 · CA

Macrophages as modulators of T cell function and therapeutic response in clear cell renal cell carcinoma

$495,125
Abraham Ari Hakimi · Sloan-Kettering Inst Can Research · R01 · FY2022 · CA

Clinical trials employing cancer vaccine combination therapies

$494,990
James L. Gulley · Division Of Basic Sciences - Nci · ZIA · FY2021 · CA

Cancer Therapy Clinical Trials Using Novel Recombinant Vaccines

$494,990
James L. Gulley · Division Of Basic Sciences - Nci · ZIA · FY2021 · CA

FEEDBACK CONTROL OF THE CELL CYCLE

$494,963
Harvard University · R37 · FY2003 · GM

Tumor Organoid-Mediated Drug Testing and Clonality Analysis in Peritoneal Surface Disease of Intestinal Origin

$494,928
Konstantinos Votanopoulos · Wake Forest University Health Sciences · R01 · FY2022 · CA

Translational Immunology

$494,832
Mark Gilbert · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA

Rare Central Nervous System Cancers Initiative

$494,832
Mark Gilbert · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA

Uncover the role of H3.3-G343R mutation in shaping the DNA damage response, anti-tumor immunity and mechanisms of resistance in glioma.

$494,713
Maria G Castro · University Of Michigan At Ann Arbor · R01 · FY2024 · NS

Controllable In Vivo Genome Editing for Immune-Checkpoint Blockade in Solid Tumors

$494,605
Sheng Tong · University Of Kentucky · R01 · FY2022 · EB

INTERACITONS OF HPV ONCOGENES WITH THE P53 PATHWAY

$494,537
Fred Hutchinson Cancer Research Center · R01 · FY2004 · CA

Controllable In Vivo Genome Editing for Immune-Checkpoint Blockade in Solid Tumors

$494,410
Sheng Tong · University Of Kentucky · R01 · FY2021 · EB

Role of Tspan5 in MHC I antigen presentation and cancer immune evasion

$494,409
Kenneth L Rock · Univ Of Massachusetts Med Sch Worcester · R01 · FY2024 · AI

IL-17-driven mechanisms for tumor progression and resistance to therapies

$494,293
Thaddeus S Stappenbeck · Cleveland Clinic Lerner Com-Cwru · P01 · FY2024 · CA

Tumor Organoid-Mediated Drug Testing and Clonality Analysis in Peritoneal Surface Disease of Intestinal Origin

$494,277
Konstantinos Votanopoulos · Wake Forest University Health Sciences · R01 · FY2023 · CA

Nanoscale Metal-Organic Frameworks Enable Radiotherapy-Radiodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Generate Tumor Vaccines and Potentiate Immunotherapy of Head and Neck Cancers

$494,273
Wenbin Lin · University Of Chicago · R01 · FY2022 · CA

Nanoscale Metal-Organic Frameworks Enable Radiotherapy-Radiodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Generate Tumor Vaccines and Potentiate Immunotherapy of Head and Neck Cancers

$494,273
Wenbin Lin · University Of Chicago · R01 · FY2023 · CA

Ultrasmall particle-based solutions for inducing ferroptosis and improving anti-tumor immune responses in cancer

$494,251
Michelle S Bradbury · Weill Medical Coll Of Cornell Univ · R01 · FY2024 · CA

Alpha particles combined with ATR inhibition to activate the immune system: mechanisms and pre-clinical translation

$494,190
Gabriel Oliveira Sawakuchi · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

Radioprotective effect of p53 against oral mucositis

$494,189
Chang-Lung Lee · Duke University · R01 · FY2024 · DE

Unraveling the Impact of Extracellular Vesicle-Loaded FXR1 mRNA on Re-educating Cancer Microenvironment

$494,160
Pradeep Chaluvally-Raghavan · Medical College Of Wisconsin · R01 · FY2025 · CA